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Series GSE26875 Query DataSets for GSE26875
Status Public on Jan 26, 2011
Title Gene expression data from undifferentiated mouse embryonal carcinoma cell strains (MOE430A and MOE430B)
Organism Mus musculus
Experiment type Expression profiling by array
Summary Gene expression profiles of undifferentiated mouse embryonal carcinoma cell strains (P19, P19CL6, and 4 P19CL6 sublines) were obtained, using Affymetrix GeneChip Mouse Genome 430A and 430B.
Heart diseases such as cardiac infarction damage cardiomyocytes and consequently lead to significant loss of the contractile capacity of the heart. To repair functions of the injured heart, a great deal of research has attempted to develop regenerative medicine using pluripotent stem cell-based cardiomyocytes as cell therapy products. However, the efficiency of the current methods available for the cardiac differentiation of stem cells is insufficient for clinical settings. A comprehensive understanding of the mechanism involved in the cardiac differentiation of stem cells is necessary to improve the differentiation efficiency. To identify genes assosiated with cardiomyogenic potential, we isolated P19CL6 cell sublines possessing distinct properties in cardiomyogenesis and comprared their transcriptome profiles with those of mouse embryonal carcinoma P19 and P19CL6 cells.
 
Overall design Total RNA isolated from undifferentiated EC cell strains (P19 cells, P19CL6 cells, and 4 P19CL6 sublines) using Affymetrix chips MOE430A and MOE430AB.

CEL files unavailable.
 
Contributor(s) Sato Y, Hasegawa T, Yasuda S, Hosono T, Satoh M, Watanabe K, Ono K, Shimizu S, Hayakawa T, Yamaguchi T, Suzuki K
Citation(s) 21554246
Submission date Jan 26, 2011
Last update date Jan 08, 2019
Contact name Yoji Sato
E-mail(s) yoji@nihs.go.jp
Phone +81-3-3700-1141
Fax +81-3-3707-6950
Organization name NIHS
Department Cell. Gene Thpy. Prod.
Street address 1-18-1 Kami-yoga
City Setagaya
State/province Tokyo
ZIP/Postal code 158-8501
Country Japan
 
Platforms (2)
GPL339 [MOE430A] Affymetrix Mouse Expression 430A Array
GPL340 [MOE430B] Affymetrix Mouse Expression 430B Array
Samples (60)
GSM661575 P19CL6, biological rep1 (MOE430A)
GSM661576 P19CL6, biological rep2 (MOE430A)
GSM661577 P19CL6, biological rep3 (MOE430A)
Relations
BioProject PRJNA136115

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Supplementary data files not provided
Processed data included within Sample table
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