|
| Status |
Public on Apr 03, 2012 |
| Title |
Gene expression profiling of Acute Myeloid Leukemia (AML) samples |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
The aim was to analyze the expression of genes in cytogenetically distinct cases of AML.
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| |
|
| Overall design |
We used total RNA obtained from 6 AML samples, consisting of 3 cytogenetically distinct subtypes, to establish the expression levels of 27,868 individual human genes. Expression data from the ABI Human Genome Survey Microarray were filtered, quantile-normalized and subjected to significance analysis of microarrays. Established gene expression profiles were further compared with corresponding DNA methylation in analyzed AML patients.
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| |
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| Contributor(s) |
Marzec J, Wang J, Saied M, Young BD, Debernardi S |
| Citation(s) |
22479372 |
| |
| Submission date |
Dec 27, 2011 |
| Last update date |
Apr 06, 2012 |
| Contact name |
Jacek Dariusz Marzec |
| E-mail(s) |
j.marzec@qmul.ac.uk
|
| Organization name |
Barts Cancer Institute
|
| Department |
Centre for Haemato-Oncology
|
| Lab |
Cancer Genomics
|
| Street address |
Charterhouse Square
|
| City |
London |
| ZIP/Postal code |
EC1M 6BQ |
| Country |
United Kingdom |
| |
|
| Platforms (1) |
| GPL9851 |
ABI Human Genome Survey Microarray v.1 |
|
| Samples (6)
|
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| This SubSeries is part of SuperSeries: |
| GSE37022 |
Genome-Wide Analysis of Acute Myeloid Leukemia Reveals Leukemia-Specific Methylome and Subtype-Specific Hypomethylation of Repeats |
|
| Relations |
| BioProject |
PRJNA150437 |
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