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| Status |
Public on Sep 01, 2012 |
| Title |
ChIP-on-chip from murine myeloid cell line M1 and virus-induced myeloid leukemia cell lines for H3K4me3, H3K9/14ac, H3K4me1, H3K27me3, H3K9me3 and CTCF |
| Organism |
Mus musculus |
| Experiment type |
Genome binding/occupancy profiling by array
|
| Summary |
Histone modifcations and CTCF binding at the c-myb locus were compared in cell lines with c-myb expressing, which are myeloblatic M1 cells and leukemia cells with virus integration, VS. M1 cells without c-myb expression induced by IL-6. Distribution of active histone marks at the c-myb gene and the upstream regions are associated with active c-myb transcription. The enrichment of all of these active histone marks decreased with differentiation-induced down-regulation of c-myb, but increased and spread in tumor cells.
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| |
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| Overall design |
ChIP-on-chip from murine myeloid cell line M1 and virus-induced myeloid leukemia cell lines for H3K4me3, H3K9/14ac, H3K4me1, H3K27me3, H3K9me3 and CTCF
|
| |
|
| Contributor(s) |
Zhang J, Wolff L |
| Citation(s) |
22811527 |
| |
| Submission date |
Dec 29, 2011 |
| Last update date |
Nov 06, 2012 |
| Contact name |
Junfang Zhang |
| E-mail(s) |
zhangj3@mail.nih.gov
|
| Phone |
301-402-9232
|
| Fax |
301-594-3996
|
| Organization name |
NIH
|
| Department |
NCI-CCR
|
| Lab |
Laboratory of Cellular Oncology
|
| Street address |
37 Convent Dr.
|
| City |
Bethesda |
| State/province |
MD |
| ZIP/Postal code |
20892 |
| Country |
USA |
| |
|
| Platforms (4)
|
| GPL15050 |
Agilent-021202 MMLv3 [Probe Name version] |
| GPL15072 |
Agilent-019497 MMLv2.0 [Probe Name version] |
| GPL15073 |
Agilent-019859 MMLv2.1 [Probe Name version] |
| GPL15074 |
Agilent-020349 MMLv2.2 [Probe Name version] |
|
| Samples (28)
|
|
| Relations |
| BioProject |
PRJNA150353 |
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