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Series GSE3512 Query DataSets for GSE3512
Status Public on Oct 28, 2005
Title Fat-type specific effects of high fat diets
Organism Rattus norvegicus
Experiment type Expression profiling by array
Summary High fat diet (HF) rodent models have contributed significantly to the dissection of the pathophysiology of the insulin resistance syndrome, but their phenotype varies distinctly between different studies. Here, we have analyzed gene expression patterns in livers of animals fed with different HF with varying fatty acid compositions.
Keywords: diet-gene interaction
 
Overall design Male Wistar rats were fed with high fat diets (42 energy%, fat sources: lard, olive oil; coconut fat; cod liver oil). Weight, food intake, whole body insulin tolerance and plasma parameters of glucose and lipid metabolism were measured during a 12 week diet course. Liver histologies and hepatic gene expression profiles using AffymetrixR gene chips were obtained.
 
Contributor(s) Buettner R, Parhofer K, Woenckhaus M, Wrede CE, Kunz-Schughart LA, Scholmerich J, Bollheimer LC
Citation(s) 16720718
Submission date Oct 26, 2005
Last update date Jul 31, 2017
Contact name Roland Buettner
E-mail(s) roland.buettner@klinik.uni-r.de
Phone 0049-941-944-7003
Fax 0049-041-944-7004
Organization name University of Regensburg
Department Internal Medicine I
Lab Endocrinology
Street address Franz-Josef-Strauss-Allee 11
City Regensburg
ZIP/Postal code 93042
Country Germany
 
Platforms (1)
GPL1355 [Rat230_2] Affymetrix Rat Genome 230 2.0 Array
Samples (10)
GSM78869 fasted liver lard diet 1
GSM78870 fasted liver lard diet 2
GSM78871 fasted liver olive oil diet 1
Relations
BioProject PRJNA93555

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