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Series GSE35718 Query DataSets for GSE35718
Status Public on Oct 03, 2012
Title Pulmonary gene expression in MutaTMMouse orally gavaged with three doses of benzo(a)pyrene and vehicle control
Organism Mus musculus
Experiment type Expression profiling by array
Summary In this study, we investigate mRNA profiles in lung of mice exposed to benzo(a)pyrene. Male mice were exposed to three doses (25, 50, and 75 mg/kg/day BaP) for 28 days and profiles were examined three days post-exposure. Our analyses reveal that BaP causes pulmonary specific cellular transformation indicative of carcinogenesis.
 
Overall design Individual total RNA (200 ng) from 5 mice per treatment group (control, 25mg/kg/day, 50mg/kg/day, and 75mg/kg/day) and universal reference total RNA (Stratagene, Mississauga, ON, Canada) was used to synthesize double stranded cDNA.
 
Contributor(s) Labib S, Williams A, Arlt V, White PA, Halappanavar S
Citation(s) 22610609
Submission date Feb 10, 2012
Last update date May 10, 2018
Contact name Andrew Williams
Organization name Health Canada
Street address 50 Columbine
City Ottawa
State/province ON
ZIP/Postal code K1A OK9
Country Canada
 
Platforms (1)
GPL4134 Agilent-014868 Whole Mouse Genome Microarray 4x44K G4122F (Feature Number version)
Samples (19)
GSM873885 Control.2
GSM873886 Low.Dose.7
GSM873887 Med.Dose.14
Relations
BioProject PRJNA152117

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE35718_RAW.tar 87.7 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table

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