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Status |
Public on Feb 17, 2014 |
Title |
A PGC-1alpha-dependent decrease in mitochondrial oxidative metabolism in muscle of humans with inherited insulin resistance |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by array
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Summary |
We used microarrays to assess gene expression profiling of 6 patients with a mutation (Arg1174Gln) in the tyrosine kinase domain of the insulin receptor gene (INSR) and 10 matched healthy controls
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Overall design |
Total RNA was purified from skeletal muscle and amplified to biotin-labeled aRNA and hybridized to microarray chips.
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Contributor(s) |
Vibe S |
Citation(s) |
24510228 |
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Submission date |
Mar 06, 2012 |
Last update date |
Dec 06, 2018 |
Contact name |
Vibe Skov |
E-mail(s) |
vihs@regionsjaelland.dk
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Phone |
+4526178735
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Organization name |
Roskilde Hospital
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Department |
Hematology
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Street address |
Koegevej 7-13
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City |
Roskilde |
ZIP/Postal code |
4000 |
Country |
Denmark |
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Platforms (1) |
GPL571 |
[HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array |
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Samples (16)
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Relations |
BioProject |
PRJNA153035 |