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| Status |
Public on May 14, 2009 |
| Title |
Poorly differentiated, human liposarcoma LiSa-2 cell line response to the synthetic triterpenoid CDDO |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
Analysis of poorly differentiated LiSa-2 liposarcoma (LS) cells treated with the synthetic triterpenoid, 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid (CDDO) or DMSO or a combination of CDDO and DMSO for up to 11 days. Synthetic triterpenoids exert a variety of actions, including anti-proliferative and proapoptotic effects, making them potentially useful in cancer therapy. Results provide insight into the pathogenesis of LS.
Keywords: disease state analysis, CDDO effect, time course
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| Overall design |
Temporal analysis of human liposarcoma cell line LiSa-2 subjected to treatment with a synthetic triterpenoid.
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| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Nov 21, 2005 |
| Last update date |
Mar 16, 2012 |
| Contact name |
Bartley Joseph Brown |
| E-mail(s) |
bbrown@eng.uiowa.edu
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| Phone |
319 335 6432
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| Organization name |
The University of Iowa
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| Lab |
CBCB
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| Street address |
5317
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| City |
Iowa City |
| State/province |
IA |
| ZIP/Postal code |
52242 |
| Country |
USA |
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| Platforms (1) |
| GPL2822 |
UI Human EST 37K cDNA array |
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| Samples (43)
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| GSM81060 |
HS 124 human poorly diff. liposarcoma, LiSa-2 cells, 11 days no treatment |
| GSM81061 |
HS 125 human poorly diff. liposarcoma, LiSa-2 cells, DMSO 11 days treated replicate 1 |
| GSM81062 |
HS 126 human poorly diff. liposarcoma, LiSa-2 cells, DMSO 11 days treated replicate 2 |
| GSM81063 |
HS 127 human poorly diff. liposarcoma, LiSa-2 cells, DMSO+CDDO 11 days treated replicate 1 |
| GSM81149 |
HS 128 human poorly diff. liposarcoma, LiSa-2 cells, 6 hrs no treatment |
| GSM81150 |
HS 129 human poorly diff. liposarcoma, LiSa-2 cells, 0 hrs no treatment |
| GSM81151 |
HS 130 human poorly diff. liposarcoma, LiSa-2 cells, DMSO 0 hrs treated replicate 1 |
| GSM81152 |
HS 131 human poorly diff. liposarcoma, LiSa-2 cells, DMSO 0 hrs treated replicate 2 |
| GSM81153 |
HS 132 human poorly diff. liposarcoma, LiSa-2 cells, DMSO+CDDO 0 hrs treated replicate 1 |
| GSM81154 |
HS 133 human poorly diff. liposarcoma, LiSa-2 cells, DMSO+CDDO 0 hrs treated replicate 2 |
| GSM81155 |
HS 134 human poorly diff. liposarcoma, LiSa-2 cells, DMSO+CDDO 11 days treated replicate 2 |
| GSM81504 |
HS 246 human poorly diff. liposarcoma, LiSa-2 cells, DMSO 24 hrs treated replicate 1 |
| GSM81505 |
HS 249 human poorly diff. liposarcoma, LiSa-2 cells, DMSO 24 hrs treated replicate 2 |
| GSM81506 |
HS 250 human poorly diff. liposarcoma, LiSa-2 cells, DMSO+CDDO 0 hrs treated replicate 1 |
| GSM81507 |
HS 251 human poorly diff. liposarcoma, LiSa-2 cells, DMSO 11 days treated replicate 2 |
| GSM81508 |
HS 248 human poorly diff. liposarcoma, LiSa-2 cells, DMSO+CDDO 24 hrs treated replicate 1 |
| GSM81509 |
HS 252 human poorly diff. liposarcoma, LiSa-2 cells, DMSO 6 hrs treated replicate 1 |
| GSM81510 |
HS 253 human poorly diff. liposarcoma, LiSa-2 cells, DMSO 6 hrs treated replicate 2 |
| GSM81511 |
HS 254 human poorly diff. liposarcoma, LiSa-2 cells, DMSO+CDDO 6 hrs treated replicate 1 |
| GSM81512 |
HS 255 human poorly diff. liposarcoma, LiSa-2 cells, DMSO+CDDO 6 hrs treated replicate 2 |
| GSM81513 |
HS 256 human poorly diff. liposarcoma, LiSa-2 cells, 24 hrs no treatment |
| GSM81514 |
HS 257 human poorly diff. liposarcoma, LiSa-2 cells, 11 days no treatment |
| GSM81515 |
HS 258 human poorly diff. liposarcoma, LiSa-2 cells, DMSO 11 days treated replicate 1 |
| GSM81516 |
HS 259 human poorly diff. liposarcoma, LiSa-2 cells, DMSO 11 days treated replicate 2 |
| GSM81517 |
HS 260 human poorly diff. liposarcoma, LiSa-2 cells, DMSO+CDDO 11 days treated replicate 1 |
| GSM81518 |
HS 261 human poorly diff. liposarcoma, LiSa-2 cells, 24 hrs no treatment |
| GSM81519 |
HS 262 human poorly diff. liposarcoma, LiSa-2 cells, DMSO 24 hrs treated replicate 1 |
| GSM81520 |
HS 263 human poorly diff. liposarcoma, LiSa-2 cells, DMSO 24 hrs treated replicate 2 |
| GSM81521 |
HS 264 human poorly diff. liposarcoma, LiSa-2 cells, DMSO+CDDO 24 hrs treated replicate 1 |
| GSM81522 |
HS 265 human poorly diff. liposarcoma, LiSa-2 cells, DMSO+CDDO 24 hrs treated replicate 2 |
| GSM83136 |
HS 266 human poorly diff. liposarcoma, LiSa-2 cells, DMSO+CDDO 0 hrs treated replicate 2 |
| GSM83137 |
HS 267 human poorly diff. liposarcoma, LiSa-2 cells, 6 hrs no treatment |
| GSM83138 |
HS 268 human poorly diff. liposarcoma, LiSa-2 cells, DMSO 6 hrs treated replicate 1 |
| GSM83139 |
HS 269 human poorly diff. liposarcoma, LiSa-2 cells, DMSO 6 hrs treated replicate 2 |
| GSM83140 |
HS 270 human poorly diff. liposarcoma, LiSa-2 cells, DMSO+CDDO 6 hrs treated replicate 1 |
| GSM83141 |
HS 271 human poorly diff. liposarcoma, LiSa-2 cells, DMSO+CDDO 6 hrs treated replicate 2 |
| GSM83142 |
HS 272 human poorly diff. liposarcoma, LiSa-2 cells, 6 hrs no treatment |
| GSM83143 |
HS 273 human poorly diff. liposarcoma, LiSa-2 cells, 0 hrs no treatment |
| GSM83144 |
HS 274 human poorly diff. liposarcoma, LiSa-2 cells, DMSO 0 hrs treated replicate 1 |
| GSM83145 |
HS 275 human poorly diff. liposarcoma, LiSa-2 cells, DMSO 0 hrs treated replicate 2 |
| GSM83146 |
HS 276 human poorly diff. liposarcoma, LiSa-2 cells, DMSO+CDDO 0 hrs treated replicate 1 |
| GSM83147 |
HS 277 human poorly diff. liposarcoma, LiSa-2 cells, DMSO+CDDO 0 hrs treated replicate 2 |
| GSM83148 |
HS 278 human poorly diff. liposarcoma, LiSa-2 cells, DMSO+CDDO 11 days treated replicate 2 |
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| Relations |
| BioProject |
PRJNA93767 |
| Supplementary data files not provided |
| Processed data not provided for this record |
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