|
| Status |
Public on Apr 10, 2014 |
| Title |
Pituitary Tumors cDNA SAGE Libraries |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by SAGE
|
| Summary |
Despite a considerable literature concerning the molecular pathogenesis of pituitary tumors, the mechanisms of pituitary tumors development and progression remain unknown. Four SAGE cDNA libraries were constructed using a pool of mRNA obtained from five GH-, two ACTH-secreting, and four non secreting pituitary tumors (NS), and three normal pituitaries from patients who had accidental death, using I-SAGE kit (Invitrogen). The aim of this study was to evaluate the differential gene expression profile by SAGE genes in different subtypes of pituitary tumors to contribute for understanding of pituitary tumorigenesis.
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| |
|
| Overall design |
Comparative analysis of gene expression profiles in subtypes of pituitary tumores.
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| |
|
| Contributor(s) |
Colli LM, Beatriz PM, Fernando AC, Lima DS, Silva WA, Moreira AC, Antonini SR, Vêncio RZ, Castro M |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Apr 10, 2012 |
| Last update date |
Apr 10, 2014 |
| Contact name |
Leandro Machado Colli |
| E-mail(s) |
leandroc@fmrp.usp.br
|
| Organization name |
School of Medicine of Ribeirao Preto
|
| Department |
Department of Internal Medicine
|
| Street address |
Av Bandeirantes 3900
|
| City |
Ribeirao Preto |
| State/province |
SP |
| ZIP/Postal code |
14049-900 |
| Country |
Brazil |
| |
|
| Platforms (1) |
| GPL4 |
SAGE:10:NlaIII:Homo sapiens |
|
| Samples (4)
|
| GSM912556 |
Normal Pituitary cDNA SAGE Library |
| GSM912557 |
Secreting-GH Pituitary Tumor cDNA SAGE Library |
| GSM912558 |
Non Secreting Pituitary Tumor cDNA SAGE Library |
| GSM912559 |
Secreting-ACTH Pituitary Tumors cDNA SAGE Library |
|
| Relations |
| BioProject |
PRJNA158585 |
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