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| Status |
Public on Jul 24, 2013 |
| Title |
Gene expression of abnormal uric acid synthesis animal model of silk worm Bombyx mori. |
| Organism |
Bombyx mori |
| Experiment type |
Expression profiling by array
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| Summary |
Uric acid (UA) is the final product of purine metabolism and plays an important role as a physiological antioxidant. In recent years, several different groups have reported a correlation between decreased UA in Parkinson’s disease (PD) and clinical progression and stage of PD. However, little is known about the molecular mechanisms of decreased UA under oxidative stress. We used our systematic functional annotation pipeline for silkworm genes to identify a novel UA metabolic pathway regulator under oxidative stress in a UA metabolism mutant silkworm Bombyx mori model.
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| Overall design |
Gene expression was measured in 3day of fifth instar larvae of abnormal uric acid synthesis Bombyx mori mutant of op.
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| Contributor(s) |
Tabunoki H, Ono H, Nakamura Y, Ishikawa K, Bono H |
| Citation(s) |
23894418 |
| |
| Submission date |
May 03, 2012 |
| Last update date |
Oct 23, 2013 |
| Contact name |
Hiromasa Ono |
| E-mail(s) |
hono@dbcls.rois.ac.jp
|
| Organization name |
Research Organization of Information and Systems
|
| Department |
Database Center for Life Science (DBCLS)
|
| Lab |
Mishima Lab.
|
| Street address |
National Institute of Genetics, Yata 1111
|
| City |
Mishima |
| State/province |
Shizuoka |
| ZIP/Postal code |
411-8540 |
| Country |
Japan |
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| Platforms (1) |
| GPL15525 |
Agilent-015933 Bombyx mori 015933_D_20070204 [ProbeName version] |
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| Samples (4)
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| Relations |
| BioProject |
PRJNA163103 |
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