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| Status |
Public on Jul 01, 2014 |
| Title |
Gene expression profile of STIM1 deficiency for cardiac remodeling in response to pressure overload by transverse aortic constriction (TAC) |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
STIM1 is a Ca2+ sensor of intracellular Ca2+ stores and essentially activates the Ca2+ entry channels of the plasma membrane. STIM1 is predicted to activate transient receptor potential canonical (TRPC) channels and Orai channels, and has a critical role in promoting the development of cardiac hypertrophy.
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| Overall design |
Gene array experiments were performed to analyze the effects of STIM1 deficiency using total RNA from the left ventricles of WT sham, WT TAC, STIM1KO sham and STIM1KO TAC 4 weeks after the operation.
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| Contributor(s) |
Ohba T |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Jun 14, 2012 |
| Last update date |
Apr 19, 2018 |
| Contact name |
Satoshi Kondo |
| Organization name |
Toray Industries,Inc.
|
| Department |
New Projects Development Division
|
| Street address |
Tebiro 6-10-1
|
| City |
Kamakura |
| State/province |
Kanagawa |
| ZIP/Postal code |
248-8555 |
| Country |
Japan |
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| Platforms (1) |
| GPL5642 |
3D-Gene Mouse Oligo chip 24k |
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| Samples (4)
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| Relations |
| BioProject |
PRJNA168507 |
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