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| Status |
Public on Sep 12, 2012 |
| Title |
Expression analysis of TRANSPOSABLE ELEMENT KILLER (TEK) knockdown lines |
| Organism |
Arabidopsis thaliana |
| Experiment type |
Expression profiling by array
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| Summary |
Investigation of the effect of the knockdown of AT-hook motif DNA binding nuclear matrix protein TRANSPOSABLE ELEMENT KILLER (TEK) in the Arabidopsis Landsberg erecta (Ler) background
Transposable elements (TEs) are silenced by epigenetic mechanisms of DNA and histone methylation. The repressive histone modification H3 lysine 9 dimethylation (H3K9me2) is TE-associated epigenetic hallmark, and is necessary for DNA methylation. However the mechanism to direct the repressive epigenetic modification in TEs has remained elusive. Here we show that knockdown of the AT-hook motif DNA binding nuclear matrix protein TRANSPOSABLE ELEMENT KILLER (TEK) in the Arabidopsis Landsberg erecta (Ler) background results in robust activation of various TEs, the repeat-containing floral repressor gene FWA and the TE-containing floral repressor FLOWERING LOCUS C (FLC).
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| Overall design |
A four chip study using two separate wild-type seedling mRNA samples and two separate TEKi seedling mRNA samples
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| Contributor(s) |
Xu Y, Ito T |
| Citation missing |
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| |
| Submission date |
Jul 06, 2012 |
| Last update date |
Jan 02, 2015 |
| Contact name |
Yifeng Xu |
| E-mail(s) |
yifeng@tll.org.sg
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| Organization name |
Temasek Life Sciences Laboratory
|
| Street address |
1 Research Link, National University of Singapore
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| City |
Singapore |
| ZIP/Postal code |
117604 |
| Country |
Singapore |
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| Platforms (1) |
| GPL10689 |
NimbleGen Arabidopsis thaliana 4x72K Array |
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| Samples (4)
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| Relations |
| BioProject |
PRJNA170117 |
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