|
| Status |
Public on Jan 31, 2013 |
| Title |
Gene expression data from human induced Pluripotent Stem cells |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Human induced Pluripotent Stem cells (hiPSc) and their differentiated progeny have great potential for modelling disease. To realise this potential, robust protocols need to be developed for deriving authentic differentiated cell lineages and these lineages need to be rigorously characterised. We have generated hiPSc using retrovirus-mediated delivery of reprogramming factors, and have used them for characterising mid-brain dopaminergic neurons. hiPSc lines have been screened using SNP array to assess chromosomal stability, and validation of the pluripotency of the hiPSc lines is provided by Pluritest assessment of transcriptome datasets.
A mature physiological cellular model of human dopaminergic neurons.
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| |
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| Overall design |
human iPSc lines were derived from normal human dermal fibroblasts.
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| Contributor(s) |
Hartfield EM, Yamasaki-Mann M, Fernandes HJ, Vowles J, James WS, Cowley SA, Wade-Martins R |
| Citation(s) |
24586273 |
| |
| Submission date |
Jan 30, 2013 |
| Last update date |
Aug 13, 2018 |
| Contact name |
Sally A Cowley |
| E-mail(s) |
sally.cowley@path.ox.ac.uk
|
| Phone |
+44 (0) 1865 275600
|
| Organization name |
University of Oxford
|
| Department |
Sir William Dunn School of Pathology
|
| Lab |
James Martin Stem Cell Facility
|
| Street address |
South Parks Road
|
| City |
Oxford |
| ZIP/Postal code |
OX1 3RE |
| Country |
United Kingdom |
| |
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| Platforms (1) |
| GPL10558 |
Illumina HumanHT-12 V4.0 expression beadchip |
|
| Samples (3) |
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| This SubSeries is part of SuperSeries: |
| GSE43904 |
SNP and expression data from human induced Pluripotent Stem cells derived from normal human dermal fibroblasts |
|
| Relations |
| BioProject |
PRJNA188093 |
