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| Status |
Public on Mar 14, 2013 |
| Title |
Effect of Trp63 deletion on the developing vagina |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
Gene expression in the neonatal uterus and vagina from transformation related protein 63 (Trp63) conditional heterozygous and null mice was analyzed in order to identify upstream and downstream of Trp63 in the developing vagina. Differential gene expression between vaginal (Trp63 positive) and uterine (Trp63 negative) tissues should reflect both the upstream and downstream of Trp63 expression, whereas the comparison between conditional knockout and heterozygous vaginae should identify what is downstream of Trp63. Thus, the three-way comparison should identify what is upstream of Trp63.
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| Overall design |
Total RNA was extracted from the Trp63 conditional heterozygous (Trp63 flox/wt ; Pax2-cre) uteri and vaginae, and Trp63 conditional knockout (Trp63 flox/floxt ; Pax2-cre) vaginae. Total 12 samples (3 different genotype/tissue groups x 4 independent samples each).
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| Contributor(s) |
Kurita T, Ishi K |
| Citation(s) |
23830984 |
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| Submission date |
Feb 26, 2013 |
| Last update date |
Jan 16, 2019 |
| Contact name |
Takeshi Kurita |
| E-mail(s) |
takeshi.kurita@osumc.edu
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| Phone |
312-503-0525
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| Organization name |
Ohio State University
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| Department |
Molecular Virology, Immunology & Medical Genetics
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| Street address |
460 W. 12th Avenue,
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| City |
Columbus |
| State/province |
OH |
| ZIP/Postal code |
43210 |
| Country |
USA |
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| Platforms (1) |
| GPL6887 |
Illumina MouseWG-6 v2.0 expression beadchip |
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| Samples (12)
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| Relations |
| BioProject |
PRJNA192960 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE44697_RAW.tar |
15.8 Mb |
(http)(custom) |
TAR |
| GSE44697_non-normalized.txt.gz |
3.4 Mb |
(ftp)(http) |
TXT |
| Processed data included within Sample table |
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