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| Status |
Public on Aug 02, 2013 |
| Title |
High-resolution custom array spanning Xq28 region to study patients carrying MECP2 copy number gain (part 1) |
| Organism |
Homo sapiens |
| Experiment type |
Genome variation profiling by genome tiling array
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| Summary |
The goal of this experiment was to determine the size, genomic extent and gene content of each Xq28 rearrangement.
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| Overall design |
We designed a tiling-path oligonucleotide microarray spanning 4.6 Mb surrounding the MECP2 region on Xq28. The custom 4x44k Agilent Technologies microarray was designed using the Agilent earray website. We selected 22,000 probes covering ChrX: 150,000,000-154,600,000 (NCBI build 36), including the MECP2 gene, which represents an average distribution of 1 probe per 209 bp. Each patient sample was run once using this array; hybridization was done using a gender-matched reference sample.
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| Contributor(s) |
Carvalho C, Pehlivan D |
| Citation(s) |
24056715 |
| |
| Submission date |
Aug 01, 2013 |
| Last update date |
Nov 13, 2013 |
| Contact name |
James Lupski |
| E-mail(s) |
jluspki@bcm.tmc.edu
|
| Organization name |
Baylor College of Medicine
|
| Street address |
One Baylor Plaza, 604B
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| City |
Houston |
| ZIP/Postal code |
77030 |
| Country |
USA |
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| Platforms (1) |
| GPL17521 |
Agilent-025384 Homo sapiens Xq28_2009 |
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| Samples (22)
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| This SubSeries is part of SuperSeries: |
| GSE49447 |
High-resolution custom array spanning Xq28 region to study patients carrying MECP2 copy number gain |
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| Relations |
| BioProject |
PRJNA213953 |
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