|
| Status |
Public on Dec 23, 2013 |
| Title |
Deletion of conserved protein phosphatases reverses defects associated with mitochondrial DNA damage in Saccharomyces cerevisiae |
| Organism |
Saccharomyces cerevisiae |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Mitochondrial biogenesis is regulated by signaling pathways sensitive to extracellular conditions and to the internal environment of the cell. We found that deletion of protein phosphatase 2A (PP2A) or of protein phosphatase 6 (PP6) diminishes the nuclear transcriptional response associated with mtDNA damage.
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| |
|
| Overall design |
Six samples were analyzed to determine message RNA levels.
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| |
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| Contributor(s) |
Garipler G, Mutlu N, Lack NA, Dunn CD |
| Citation(s) |
24474773 |
| Submission date |
Nov 08, 2013 |
| Last update date |
May 15, 2019 |
| Contact name |
Cory David Dunn |
| E-mail(s) |
cdunn@ku.edu.tr
|
| Organization name |
Koç University
|
| Department |
Molecular Biology and Genetics
|
| Street address |
Rumelifeneri Yolu
|
| City |
Sariyer |
| State/province |
Istanbul |
| ZIP/Postal code |
34450 |
| Country |
Turkey |
| |
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| Platforms (1) |
| GPL13821 |
Illumina HiSeq 2000 (Saccharomyces cerevisiae) |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA227236 |
| SRA |
SRP032818 |
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