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Series GSE53713 Query DataSets for GSE53713
Status Public on Jan 28, 2014
Title Expression data from mouse E14.5 fetal liver SLAM LSKs
Organism Mus musculus
Experiment type Expression profiling by array
Summary To determine genes in FL HSCs that are sensitive to Notch signagling, E14.5 FL cells were cultured on DL1( to stimulate Notch signaling). Cells were cultured in the presence of DMSO (vehicle control) or gamma secretase inhibitor (1uM) for 4 hrs or 10hrs. Gamma secretase inhibitor was used to inhibit Notch signaling. SLAM-LSKs were sorted and used for RNA preparation.
 
Overall design 7 biological replicates (14 totalt samples) were collected for cells cultured for 4hrs. 4 biological replicates (8 total samples) were collected from cells cultured for 10hrs. Each replicate consisted of a DMSO and GSI treated sample
 
Contributor(s) Gerhardt D, Pear WS
Citation(s) 24637115
Submission date Dec 30, 2013
Last update date Feb 21, 2018
Contact name dawson gerhardt
E-mail(s) dawsonm@upenn.edu
Organization name University of Pennsylvania
Street address BRB2/3 421 Curie Blvd.
City Philadelphia
ZIP/Postal code 19104
Country USA
 
Platforms (1)
GPL16570 [MoGene-2_0-st] Affymetrix Mouse Gene 2.0 ST Array [transcript (gene) version]
Samples (22)
GSM1299305 WT E14.5 FL SLAM LSK 4h DMSO Rep1
GSM1299306 WT E14.5 FL SLAM LSK 4h GSI Rep1
GSM1299307 WT E14.5 FL SLAM LSK 4h DMSO Rep2
Relations
BioProject PRJNA232709

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE53713_RAW.tar 192.9 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table
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