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Series GSE56954 Query DataSets for GSE56954
Status Public on Jan 07, 2015
Title A687V EZH2 is a driver of histone H3 lysine 27 (H3K27) hyper-trimethylation
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Gene expression changes were analyzed in 2 acute lymphoblastic leukemia cell lines treated with the GSK126 EZH2 inhibitor using Affymetrix Human Genome U133 Plus 2.0 arrays.
 
Overall design Two ALL cell lines (SUP-B8, NALM-6) were treated with DMSO (control) or GSK126 at 0.5 uM for 72 hours. Two biological replicates are included for each treatment group.
 
Contributor(s) Ott H, Bai Y, Creasy C, McCabe M
Citation(s) 25253781
Submission date Apr 21, 2014
Last update date Mar 25, 2019
Contact name Matteo Righi
E-mail(s) m.righi@autolus.com
Organization name Autolus Therapeutics
Street address The MediaWorks, 191 Wood Ln
City London
State/province London
ZIP/Postal code W12 7FP
Country United Kingdom
 
Platforms (1)
GPL570 [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Samples (8)
GSM1372113 SUP-B8 DMSO vehicle at 72 hrs, Biological rep1
GSM1372114 SUP-B8 DMSO vehicle at 72 hrs, Biological rep2
GSM1372115 SUP-B8 GSK126 0.5 uM at 72 hrs, Biological rep1
Relations
BioProject PRJNA245049

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE56954_RAW.tar 41.7 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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