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Status |
Public on Mar 15, 2018 |
Title |
Heart expression data from WT mice at ZT12 after short ischemia/reperfusion +/- Reverb alpha antagonist treatment |
Organism |
Mus musculus |
Experiment type |
Expression profiling by array
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Summary |
Nuclear receptor Reverb alpha is a component of circadian rythm which could be evolved in cardioprotection strategy. We test if pharmacological modulation of these target could be suitable for cardioprotection after ischemia reperfusion injury We used microarrays to detail the global programme of gene expression
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Overall design |
heart ischemia reperfusion were performed using Langendorff isolated heart model and twenty minutes stop flow ishemia with twenty minutes reperfusion.
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Contributor(s) |
Marechal X, Montaigne D, Gheeraert C, Lefebvre P |
Citation(s) |
29107324 |
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Submission date |
Oct 17, 2014 |
Last update date |
Nov 13, 2023 |
Contact name |
Lefebvre Philippe |
Organization name |
Inserm
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Lab |
U1011
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Street address |
Blvd Pr. J.Leclerc
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City |
Lille |
State/province |
Nord |
ZIP/Postal code |
59000 |
Country |
France |
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Platforms (1) |
GPL16570 |
[MoGene-2_0-st] Affymetrix Mouse Gene 2.0 ST Array [transcript (gene) version] |
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Samples (5)
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GSM1527299 |
Heart at ZT12, WT mouse, SHAM, biological rep1 |
GSM1527300 |
Heart at ZT12, WT mouse, SHAM, biological rep2 |
GSM1527301 |
Heart at ZT12, WT mouse + reverb alpha antagonist, biological rep1 |
GSM1527302 |
Heart at ZT12, WT mouse + reverb alpha antagonist, biological rep2 |
GSM1527303 |
Heart at ZT12, WT mouse + reverb alpha antagonist, biological rep3 |
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This SubSeries is part of SuperSeries: |
GSE62459 |
Heart expression data after short ischemia/reperfusion in WT, Reverb alpha KO and Reverb alpha antagonist-treated mice |
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Relations |
BioProject |
PRJNA264172 |