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| Status |
Public on Mar 16, 2015 |
| Title |
Comparison of gene expression in aorta and CD115+ isolated circulating cells from apoE-/- versus apoE-/-LTbR-/- mice |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
Affymetrix Microarrays were used to analyse gene expression in aortas and circulating CD115+ cells of ApoE- and ApoE/Lymphotoxin beta receptor (LTbR)-double-deficent mice fed a Western diet from 8 to 12 weeks of age in order to identify regulated genes and pathways leading to reduced atherosclerosis in ApoE-/-/LTbR-/- mice compared to ApoE-/- littermate controls.
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| Overall design |
Gene expression was analysed in aorta and CD115+ circulating blood cells in ApoE-and ApoE/LTbR-double deficient mice after 4 weeks feeding a high-fat, high-cholesterol Western type diet.
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| Contributor(s) |
Grandoch M, Feldmann K, Göthert JR, Homann S, Dick LS, Bayer JK, Klatt C, Waldheim JN, Rabausch B, Nagy N, Oberhuber A, Deenen R, Köhrer K, Lehr S, Homey B, Pfeffer K, Fischer JW |
| Citation(s) |
25740843 |
| |
| Submission date |
Nov 13, 2014 |
| Last update date |
Feb 21, 2018 |
| Contact name |
Karl Koehrer |
| E-mail(s) |
rene.deenen@hhu.de
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| Organization name |
University of Duesseldorf
|
| Department |
BMFZ
|
| Lab |
GTL
|
| Street address |
Universitaetsstr. 1
|
| City |
Duesseldorf |
| ZIP/Postal code |
40225 |
| Country |
Germany |
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| Platforms (1) |
| GPL16570 |
[MoGene-2_0-st] Affymetrix Mouse Gene 2.0 ST Array [transcript (gene) version] |
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| Samples (14)
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| Relations |
| BioProject |
PRJNA267119 |
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