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| Status |
Public on Sep 09, 2015 |
| Title |
Association of Taf14 with acetylated histone H3 directs the DNA damage response and gene transcription |
| Organism |
Saccharomyces cerevisiae |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We sequenced mRNA from triplicate log-phase cultures of BY4741 (WT) transformed with pRS313-HA3-SSN6 and taf14D transformed with pRS313-HA3-SSN6 (empty vector), full-length pRS313-TAF14-HA3-SSN6, or pRS313-taf14W81A-HA3-SSN6 cultured in synthetic complete media lacking histidine.
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| |
|
| Overall design |
Examination of changes in gene expression when the YEATS domain of Taf14 is mutated so it cannot bind acetyl-H3.
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| |
|
| Contributor(s) |
Shanle EK, Strahl BD |
| Citation(s) |
26341557 |
| Submission date |
Aug 05, 2015 |
| Last update date |
May 15, 2019 |
| Contact name |
Erin K Shanle |
| E-mail(s) |
eshanle7@gmail.com
|
| Organization name |
University of North Carolina at Chapel Hill
|
| Department |
Biochemistry and Biophysics
|
| Lab |
Brian D. Strahl
|
| Street address |
3010 Genetic Medicine, 120 Mason Farm Road
|
| City |
Chapel Hill |
| State/province |
NC |
| ZIP/Postal code |
27599 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL13821 |
Illumina HiSeq 2000 (Saccharomyces cerevisiae) |
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| Samples (12)
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| Relations |
| BioProject |
PRJNA292038 |
| SRA |
SRP062085 |
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