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Series GSE72665 Query DataSets for GSE72665
Status Public on Nov 30, 2015
Title Rare CNVs in Lynch Syndrome patients negative for mutations in mismatch repair genes [Agilent]
Organism Homo sapiens
Experiment type Genome variation profiling by genome tiling array
Summary Only a small proportion of cases suspected to have Lynch Syndrome (LS) can be explained by mutation in the mismatch repair (MMR) genes. This study aimed to identify rare CNVs that may contribute to an increased risk for hereditary colorectal cancer in patients with MMR proficiency.
 
Overall design Genomic DNA was extracted from the blood of 54 unrelated patients who met criteria for LS (Amsterdam or Bethesda). Genomic alterations were evaluated using the Agilent-022060 4x180K microarray platform. The reference was a pool of normal male DNA (Promega, cat. no. G1471) or normal female DNA (Promega, cat.no. G1521).
 
Contributor(s) Villacis RA
Citation missing Has this study been published? Please login to update or notify GEO.
Submission date Sep 02, 2015
Last update date Dec 01, 2015
Contact name Rolando Andre Rios Villacis
E-mail(s) rolando.andre@unb.br
Phone +5561996912223
Organization name University of Brasília - UnB
Department Genetics and Morphology
Lab Genetic Toxicology
Street address Asa Norte
City Brasília
State/province DF
ZIP/Postal code 70910-900
Country Brazil
 
Platforms (1)
GPL10150 Agilent-022060 SurePrint G3 Human CGH Microarray 4x180K (Probe Name version)
Samples (45)
GSM1867861 Patient 1 [Agilent]
GSM1867863 Patient 2 [Agilent]
GSM1867865 Patient 3 [Agilent]
This SubSeries is part of SuperSeries:
GSE72668 Rare CNVs in Lynch Syndrome patients negative for mutations in mismatch repair genes
Relations
BioProject PRJNA294620

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE72665_RAW.tar 2.2 Gb (http)(custom) TAR (of TXT)
Processed data included within Sample table

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