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| Status |
Public on Dec 30, 2015 |
| Title |
Expression of lncRNAs in mouse heart 4 weeks after myocardial infarction |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
Non-coding RNA profiling by array
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| Summary |
The expression signature of lncRNAs and mRNAs was analyzed in fibrotic tissue from peri-infarct region of mouse heart. We fund that fifty seven differentially expressed lncRNAs and 20 differentially expressed mRNAs are associated with 8 signaling pathways which are involved in the development of cardiac fibrosis, indicating a potential role of lncRNAs in cardiac fibrosis.
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| Overall design |
Male C57BL/6 mice was used to establish a myocardial infartion model by ligating the left anterior descending coronary artery. After 4 weeks, we collected the peri-infarct tissues from MI mice and corresponding region from sham-operated group for RNA extraction and hybridization on Affymetrix microarrays.
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| Contributor(s) |
Qu X, Song X, Yuan w, Shu Y, Sun L, Lu Y |
| Citation(s) |
27129287 |
| |
| Submission date |
Dec 29, 2015 |
| Last update date |
Jun 09, 2017 |
| Contact name |
Xuefeng Qu |
| E-mail(s) |
914316764@qq.com
|
| Phone |
+86 18045183552
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| Organization name |
Harbin Medical University
|
| Department |
Department of Pharmacology
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| Street address |
157 Baojian Road
|
| City |
Harbin |
| State/province |
Heilongjiang |
| ZIP/Postal code |
150081 |
| Country |
China |
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| Platforms (1) |
| GPL20775 |
[MTA-1_0] Affymetrix Mouse Transcriptome Array 1.0 [transcript (gene) CSV version] |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA307167 |
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