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| Status |
Public on Mar 01, 2017 |
| Title |
Molecular profiling of the developing lacrimal gland |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
Although normal function of the lacrimal gland (LG) is essential for vision (and thus, for human well-being), the LG remains rather poorly understood at molecular level. The purpose of this study was to identify new genes and signaling cascades involved in LG development.
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| Overall design |
To characterize and compare lacrimal glands isolated from embryonic and adult mice, we studied gene expression in these glands using Mouse Exonic Evidence Based Oligonucleotide (MEEBO) microarrays. To perform this experiment, RNA extracted from lacrimal glands of 3-month-old (adult) mice and embryonic day 16.5 (E16.5) fetuses was used for microarray analysis. A total of three independent biological replicates of E16.5 lacrimal glands and three independent biological replicates of adult lacrimal glands were obtained for comparative profiling.
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| Contributor(s) |
Ivanov D, Pelaez D |
| Citation(s) |
28192800 |
| |
| Submission date |
Feb 18, 2016 |
| Last update date |
Mar 08, 2017 |
| Contact name |
Dmitry Ivanov |
| E-mail(s) |
divanov@med.miami.edu
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| Phone |
305-482-4230
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| Organization name |
University of Miami Miller School of Medicine
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| Department |
Ophthalmology
|
| Street address |
1638 NW 10th Avenue
|
| City |
Miami |
| State/province |
FL |
| ZIP/Postal code |
33136 |
| Country |
USA |
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| Platforms (1) |
| GPL7656 |
Mouse Exonic Evidence Based Oligonucleotide (MEEBO) spotted microarrays |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA312489 |
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