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| Status |
Public on May 27, 2016 |
| Title |
SNAI1 overexpression effect on MCF-10A mammary epithelial cell line (miRNA) |
| Platform organism |
synthetic construct |
| Sample organism |
Homo sapiens |
| Experiment type |
Non-coding RNA profiling by array
|
| Summary |
SNAI1 is a key transcription factor in the EMT process, that is considered as the initial step of metastasis. The microRNAs(miRNAs) invovled in SNAI1-induced EMT may play important roles in regulating the process of metastasis.
We used microarrays to establish the miRNAs both upregulated and downregulated in SNAI1-induced EMT process.
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| Overall design |
MCF-10A mammary epithelial cells were transfected with either SNAI1 (L) or a control vector (C) were harvested for RNA extraction and hybridization on Affymertix microarrays. 3 biological repetitions were done for microarray analysis.
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| |
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| Contributor(s) |
Liu Z, Zhan Y |
| Citation(s) |
27894095 |
| |
| Submission date |
May 26, 2016 |
| Last update date |
May 02, 2017 |
| Contact name |
Zhihua Liu |
| E-mail(s) |
liuzh@cicams.ac.cn
|
| Phone |
8610-67723789
|
| Organization name |
National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
|
| Street address |
NO.17 Nanli, Panjiayuan Road, Chaoyang District
|
| City |
Beijing |
| ZIP/Postal code |
100021 |
| Country |
China |
| |
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| Platforms (1) |
| GPL14613 |
[miRNA-2] Affymetrix Multispecies miRNA-2 Array |
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| Samples (6)
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| This SubSeries is part of SuperSeries: |
| GSE81931 |
SNAI1 overexpression effect on MCF-10A mammary epithelial cell line |
|
| Relations |
| BioProject |
PRJNA323454 |
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