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| Status |
Public on Jun 30, 2021 |
| Title |
Major MLL fusion partners regulate promoter-proximal pausing and release of RNA polymerase II |
| Organisms |
Homo sapiens; Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
Other
Genome binding/occupancy profiling by high throughput sequencing
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| Summary |
1Sheng Yushou Center of Cell Biology and Immunology, Department of Genetics and Developmental Biology, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, 200240, China. 2Laboratory of Biochemistry and Molecular Biology, The Rockefeller University, New York, NY 10065, USA. 3Systems Biology Center, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA. 4CCTS Bioinformatic Program, The Rockefeller University, New York, NY 10065, USA. 5State Key Laboratory of Genetic Engineering & Ministry of Education Key Laboratory of Contemporary Anthropology, Collaborative Innovation Center of Genetics and Development, School of Life Sciences, Fudan University, Shanghai, 200438, China
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| Overall design |
Study the roles of major fusion partners of MLL1 in mixed lineage leukemia, including AFF1, AFF4, AF9, and ENL, and H3K79 methyltransferase, DOT1L, in transcriptional regulation by ChIP-seq, RNA-seq, and Pro-seq.
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| Contributor(s) |
Roeder RG, Yu M, Yang W, Liang Y, Wei G |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Jul 07, 2016 |
| Last update date |
Jun 30, 2021 |
| Contact name |
Gang Wei |
| E-mail(s) |
gwei@fudan.edu.cn
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| Phone |
+862151630626
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| Organization name |
Fudan University
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| Street address |
No 2005, Songhu Rd, Yangpu District
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| City |
Shanghai |
| State/province |
Select a State or Province |
| ZIP/Postal code |
200438 |
| Country |
China |
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| Platforms (2) |
| GPL11002 |
Illumina Genome Analyzer IIx (Mus musculus) |
| GPL11154 |
Illumina HiSeq 2000 (Homo sapiens) |
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| Samples (49)
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| Relations |
| BioProject |
PRJNA328160 |
| SRA |
SRP078067 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE84157_Lib1.bedGraph.gz |
40.7 Mb |
(ftp)(http) |
BEDGRAPH |
| GSE84157_Lib119.bedGraph.gz |
45.5 Mb |
(ftp)(http) |
BEDGRAPH |
| GSE84157_Lib121.bedGraph.gz |
24.4 Mb |
(ftp)(http) |
BEDGRAPH |
| GSE84157_Lib179.bedGraph.gz |
42.7 Mb |
(ftp)(http) |
BEDGRAPH |
| GSE84157_Lib179_targets.txt.gz |
254.2 Kb |
(ftp)(http) |
TXT |
| GSE84157_Lib196.bedGraph.gz |
40.9 Mb |
(ftp)(http) |
BEDGRAPH |
| GSE84157_Lib196_targets.txt.gz |
25.7 Kb |
(ftp)(http) |
TXT |
| GSE84157_Lib1_targets.txt.gz |
265.9 Kb |
(ftp)(http) |
TXT |
| GSE84157_Lib202.bedGraph.gz |
20.5 Mb |
(ftp)(http) |
BEDGRAPH |
| GSE84157_Lib203.bedGraph.gz |
23.1 Mb |
(ftp)(http) |
BEDGRAPH |
| GSE84157_Lib214.bedGraph.gz |
38.5 Mb |
(ftp)(http) |
BEDGRAPH |
| GSE84157_Lib214_targets.txt.gz |
455.0 Kb |
(ftp)(http) |
TXT |
| GSE84157_Lib216.bedGraph.gz |
22.5 Mb |
(ftp)(http) |
BEDGRAPH |
| GSE84157_Lib217.bedGraph.gz |
20.7 Mb |
(ftp)(http) |
BEDGRAPH |
| GSE84157_Lib228.bedGraph.gz |
19.7 Mb |
(ftp)(http) |
BEDGRAPH |
| GSE84157_Lib229.bedGraph.gz |
16.9 Mb |
(ftp)(http) |
BEDGRAPH |
| GSE84157_Lib23.bedGraph.gz |
38.4 Mb |
(ftp)(http) |
BEDGRAPH |
| GSE84157_Lib230.bedGraph.gz |
17.2 Mb |
(ftp)(http) |
BEDGRAPH |
| GSE84157_Lib231.bedGraph.gz |
24.2 Mb |
(ftp)(http) |
BEDGRAPH |
| GSE84157_Lib23_targets.txt.gz |
274.0 Kb |
(ftp)(http) |
TXT |
| GSE84157_Lib246.bedGraph.gz |
16.5 Mb |
(ftp)(http) |
BEDGRAPH |
| GSE84157_Lib247.bedGraph.gz |
18.7 Mb |
(ftp)(http) |
BEDGRAPH |
| GSE84157_Lib248.bedGraph.gz |
387.1 Mb |
(ftp)(http) |
BEDGRAPH |
| GSE84157_Lib249.bedGraph.gz |
375.7 Mb |
(ftp)(http) |
BEDGRAPH |
| GSE84157_Lib27_targets.txt.gz |
908.2 Kb |
(ftp)(http) |
TXT |
| GSE84157_Lib91.bedGraph.gz |
44.2 Mb |
(ftp)(http) |
BEDGRAPH |
| GSE84157_ProLib10_outputFile.txt.gz |
11.1 Kb |
(ftp)(http) |
TXT |
| GSE84157_ProLib11_outputFile.txt.gz |
11.3 Kb |
(ftp)(http) |
TXT |
| GSE84157_ProLib12_outputFile.txt.gz |
11.1 Kb |
(ftp)(http) |
TXT |
| GSE84157_ProLib3_outputFile.txt.gz |
11.0 Kb |
(ftp)(http) |
TXT |
| GSE84157_ProLib4_outputFile.txt.gz |
11.1 Kb |
(ftp)(http) |
TXT |
| GSE84157_ProLib5_outputFile.txt.gz |
9.7 Kb |
(ftp)(http) |
TXT |
| GSE84157_RPKM_AFF1_and_AF9.xlsx |
2.9 Mb |
(ftp)(http) |
XLSX |
| GSE84157_RPKM_AFF4__ENL__and_DOT1L.xls.gz |
1.1 Mb |
(ftp)(http) |
XLS |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data are available on Series record |
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