|
| Status |
Public on Dec 03, 2016 |
| Title |
Candida albicans: Control vs. sulfite-treated cells |
| Organism |
Candida albicans |
| Experiment type |
Expression profiling by array
|
| Summary |
Transcriptional profiling of Candida albicans cells comparing control untreated C. albicans cells with sulfite-treated C. albicans cells. Sulfite is a toxic molecule that C. albicans encounters in its human host. Both wild type and ∆zcf2 mutant cells were used. The goal was to determine the effects of sulfite on C. albicans gene expression, and to determine which of the genes areZcf2-depedent.
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| |
|
| Overall design |
Two-condition experiment, C. albicans cells vs. sulfite-treated C. albicans cells. 2 strains used: wild type and ∆zcf2 mutant cells. Biological replicates: 2 control replicates for each strain, 2 sulfite-treated replicates for each strain. Two technical replicates for each biological replicate in which the flourescent dyes were swapped.
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| |
|
| Contributor(s) |
Gustin M, Chebaro Y |
| Citation(s) |
28235888 |
| |
| Submission date |
Dec 02, 2016 |
| Last update date |
Mar 04, 2017 |
| Contact name |
Michael Gustin |
| E-mail(s) |
gustin@rice.edu
|
| Organization name |
Rice University
|
| Department |
Biosciences
|
| Lab |
Gustin Lab
|
| Street address |
George R. Brown Hall, W200G, 6100 Main Street
|
| City |
Houston |
| State/province |
TX |
| ZIP/Postal code |
77251 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL16243 |
Agilent-020166 Ca21_GE_plus_tiling_2.0 (Feature Number version) |
|
| Samples (8)
|
| GSM2413635 |
Control vs sulfite-treated Wild type C.albicans Replicate 1 |
| GSM2413636 |
Control vs sulfite-treated Wild type C.albicans Replicate 2 |
| GSM2413637 |
Sulfite-treated vs control Wild type C. albicans Replicate 1 |
| GSM2413638 |
Sulfite-treated vs control Wild type C. albicans Replicate 2 |
| GSM2413639 |
Control ∆zcf2 vs sulfite-treated ∆zcf2 C.albicans Replicate 1 |
| GSM2413640 |
Control ∆zcf2 vs sulfite-treated ∆zcf2 C.albicans Replicate 2 |
| GSM2413641 |
Sulfite-treated ∆zcf2 vs control ∆zcf2 C. albicans Replicate 1 |
| GSM2413642 |
Sulfite-treated ∆zcf2 vs control ∆zcf2 C. albicans Replicate 2 |
|
| Relations |
| BioProject |
PRJNA356054 |
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