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| Status |
Public on Feb 07, 2017 |
| Title |
Reseveratrol and Rosiglitazone regulation of liver gene expression in ZDF rats |
| Organism |
Rattus norvegicus |
| Experiment type |
Expression profiling by array
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| Summary |
The goal of this work was to examine if reserveratrol or rosiglitazone treatment could improve the metabolic status of obese male ZDF rats after 6 weeks. Gene expression was analyzed in several key metabolic tissues, including liver, various white adipose tissue depots, red tibalus muscle, and peripheral blood mononuclear cells.
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| Overall design |
A total of 5 microarrays were run for each group, for a total of n=20 samples. For each sample, 100 ng of total RNA was prepared for hybridization to Affymetrix Rat Gene 2.1 ST array strips, according to the manufacturer’s instructions (Affymetrix Inc., Fremont, CA, USA).
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| Contributor(s) |
Wong MH, Mutch DM |
| Citation(s) |
28257645 |
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| Submission date |
Jan 11, 2017 |
| Last update date |
Mar 20, 2018 |
| Contact name |
David M Mutch |
| E-mail(s) |
dmutch@uoguelph.ca
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| Phone |
+1-519-824-4120
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| Organization name |
University of Guelph
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| Department |
Human Health & Nutritional Sciences
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| Lab |
ANNU 308
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| Street address |
50 Stone Road East
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| City |
Guelph |
| State/province |
Ontario |
| ZIP/Postal code |
N1G 2W1 |
| Country |
Canada |
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| Platforms (1) |
| GPL19271 |
[RaGene-2_1-st] Affymetrix Rat Gene 2.1 ST Array [transcript (gene) version] |
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| Samples (20)
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| GSM2452737 |
lean control rat liver, biological rep1 |
| GSM2452738 |
lean control rat liver, biological rep2 |
| GSM2452739 |
lean control rat liver, biological rep3 |
| GSM2452740 |
lean control rat liver, biological rep4 |
| GSM2452741 |
lean control rat liver, biological rep5 |
| GSM2452742 |
rosiglitazone rat liver, biological rep1 |
| GSM2452743 |
rosiglitazone rat liver, biological rep2 |
| GSM2452744 |
rosiglitazone rat liver, biological rep3 |
| GSM2452745 |
rosiglitazone rat liver, biological rep4 |
| GSM2452746 |
rosiglitazone rat liver, biological rep5 |
| GSM2452747 |
resveratrol rat liver, biological rep1 |
| GSM2452748 |
resveratrol rat liver, biological rep2 |
| GSM2452749 |
resveratrol rat liver, biological rep3 |
| GSM2452750 |
resveratrol rat liver, biological rep4 |
| GSM2452751 |
resveratrol rat liver, biological rep5 |
| GSM2452752 |
obese rat liver, biological rep1 |
| GSM2452753 |
obese rat liver, biological rep2 |
| GSM2452754 |
obese rat liver, biological rep3 |
| GSM2452755 |
obese rat liver, biological rep4 |
| GSM2452756 |
obese rat liver, biological rep5 |
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| This SubSeries is part of SuperSeries: |
| GSE93407 |
Nutritional and Pharmaceutical Interventions in Diabetic Rats |
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| Relations |
| BioProject |
PRJNA360912 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE93403_RAW.tar |
86.5 Mb |
(http)(custom) |
TAR (of CEL) |
| Processed data included within Sample table |
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