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Series GSE9480 Query DataSets for GSE9480
Status Public on Nov 07, 2007
Title Expression data from adult rat testes treated with 3 mg/kg b.w. cadmium chloride via i.p.
Organism Rattus norvegicus
Experiment type Expression profiling by array
Summary This is a study to explore the transcriptional changes after cadmium treatment in adult rat testes at three time points (control--0 hour, 8 hour and 4 day). Cadmium is an environmental toxicant that is known to affect the male reproductive system. It disrupts the blood-testis barrier irreversibly, and affects the Sertoli-germ cells adhesion, causing germ cell depletion from the seminiferous epithelium.
Keywords: Cadmium effect in rat testes
Overall design Adult Sprague-Dawley rats treated with a single dose of cadmium chloride at 3 mg/kg b.w. by i.p. and terminated after 8 hours (n=2) and 20 hours (n=2). Testes from cadmium-treated rats and untreated (control, 0 hour, n=3) rats were harvested and total RNA were prepared. Standard Affymetrix genechip procedures were followed for the subsequent experiments. Data were analysed in MAS 5.0 and GeneSpring 7.2.
Contributor(s) Xia W, Cheng CY
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Submission date Oct 31, 2007
Last update date Jul 31, 2017
Contact name C YAN CHENG
Phone 212-327-8738
Fax 212-327-8733
Organization name POPULATION COUNCIL
Street address 1230 YORK AVENUE
State/province NY
ZIP/Postal code 10021
Country USA
Platforms (1)
GPL1355 [Rat230_2] Affymetrix Rat Genome 230 2.0 Array
Samples (7)
GSM240630 Untreated Testes, biological rep 1
GSM240631 Untreated Testes, biological rep 2
GSM240632 Untreated Testes, biological rep 3
BioProject PRJNA103255

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE9480_RAW.tar 30.4 Mb (http)(custom) TAR (of CEL, EXP)
Processed data included within Sample table

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