|
| Status |
Public on Jun 23, 2017 |
| Title |
Transient and permanent changes in DNA methylation patterns in inorganic arsenic-mediated epithelial-to-mesenchymal transition |
| Organism |
Homo sapiens |
| Experiment type |
Methylation profiling by genome tiling array
|
| Summary |
To examine the global impact of iAs on DNA methylation patterns. Genomic DNA was bisulfite converted and analyzed using Infinium MethylationEPIC BeadChip.
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| |
|
| Overall design |
DNA from NT, iAs-treated, and iAsT-reverse treated cells were bisulfite converted and used for analysis through Illumina Infinium Methylation EPIC BeadChip.
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| |
|
| Contributor(s) |
Eckstein M, Rea M, Fondufe-Mittendorf Y |
| Citation(s) |
28589171 |
| NIH grant(s) |
| Grant ID |
Grant title |
Affiliation |
Name |
| R01 ES024478 |
Diversity Supplement: The Role of Chromatin Structural and Epigenetic Changes in Arsenic-Induced Gene Expression Supplement |
UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION |
Yvonne Nsokika Fondufe-Mittendorf |
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| |
| Submission date |
Feb 22, 2017 |
| Last update date |
Jan 20, 2019 |
| Contact name |
Yvonne Nsokika Fondufe-Mittendorf |
| E-mail(s) |
y.fondufe-mittendorf@uky.edu
|
| Phone |
8593230091
|
| Organization name |
University of Kentucky
|
| Department |
Biochemistry
|
| Lab |
Mittendorf
|
| Street address |
741 South Limestone dr.
|
| City |
Lexington |
| State/province |
KY |
| ZIP/Postal code |
40536-0509 |
| Country |
USA |
| |
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| Platforms (1) |
|
| Samples (3) |
| GSM2500346 |
DNA methylation in NT cells_ Replicate 2 |
| GSM2500347 |
DNA methylation in iAsT cells_ Replicate 2 |
| GSM2500348 |
DNA methylation in iAs-rev cells_ Replicate 2 |
|
| Relations |
| BioProject |
PRJNA376448 |
