|
| Status |
Public on Nov 06, 2017 |
| Title |
Gene expression profiling of Brucella abortus-infected mouse macrophages |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
Gene expression analysis of wild-type and STING knock-out mouse bone marrow-derived macrophages (mBMDM) infected with Brucella abortus or transfected with Brucella abortus DNA.
Genes whose expression are affected by Brucella abortus in a STING-dependent manner will be identified and signaling pathways regulated by STING will be elucidated.
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| |
|
| Overall design |
Mouse BMDMs were infected with Brucella abortus or transfected with Brucella abortus DNA for 17 hours. Total RNA was extracted for array analysis.
|
| |
|
| Contributor(s) |
Oliveira SC, Barber G |
| Citation(s) |
29203515, 33989349 |
| |
| Submission date |
Mar 10, 2017 |
| Last update date |
Jun 15, 2021 |
| Contact name |
Anthony Griswold |
| E-mail(s) |
agriswold@med.miami.edu
|
| Organization name |
University of Miami
|
| Street address |
1501 NW 10th Ave, BRB 318
|
| City |
Miami |
| State/province |
FL |
| ZIP/Postal code |
33136 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL16570 |
[MoGene-2_0-st] Affymetrix Mouse Gene 2.0 ST Array [transcript (gene) version] |
|
| Samples (6)
|
| GSM2532785 |
C57BL/6_mBMDM_medium mock treatment control_17hrs |
| GSM2532786 |
STING-KO_mBMDM_medium mock treatment control_17hrs |
| GSM2532787 |
C57BL/6_mBMDM_Brucella abortus DNA transfected_17hrs |
| GSM2532788 |
STING-KO_mBMDM_Brucella abortus DNA transfected_17hrs |
| GSM2532789 |
C57BL/6_mBMDM_Brucella abortus infected_17hrs |
| GSM2532790 |
STING-KO_mBMDM_Brucella abortus infected_17hrs |
|
| Relations |
| BioProject |
PRJNA378755 |
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