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| Status |
Public on Dec 04, 2007 |
| Title |
Expression data from brain tissue of Rattus norvegicus treated with chlorpyrifos (CPF) |
| Organism |
Rattus norvegicus |
| Experiment type |
Expression profiling by array
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| Summary |
Chlorpyrifos is an organophosphorus insecticide that despite imposed restricitions on its use by the EPA, is one of the most commonly used insecticides. Although CPF is so widely used little is known about its effect on overall gene expression in vivo.
DNA microarray technology was used to determine differential gene expression resulting from chlorpyrifos (CPF) exposure.
Keywords: Dose course
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| Overall design |
Male Fisher 344 rats aged 11-12 weeks were treated with varying doses of chlorpyrifos (CPF) and terminally sacced at 96 hours post-exposure in three separate experiments. An approximate 30mg section of the frontal lobe of the brain was processed for total RNA extraction.
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| Contributor(s) |
Chan VT, Stapleton AR |
| Citation(s) |
18668222 |
| Submission date |
Dec 03, 2007 |
| Last update date |
Mar 03, 2017 |
| Contact name |
Victor Chan |
| E-mail(s) |
victor.chan@wpafb.af.mil, andrea.stapleton@wpafb.af.mil
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| Phone |
9379049501
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| Organization name |
Air Force Research Laboratory
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| Department |
Applied Biotechnology Branch
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| Street address |
2729 R St. Area B Bldg. 837
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| City |
WPAFB |
| State/province |
OH |
| ZIP/Postal code |
45433-5707 |
| Country |
USA |
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| Platforms (1) |
| GPL341 |
[RAE230A] Affymetrix Rat Expression 230A Array |
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| Samples (46)
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| GSM246131 |
Exp A_4, control (0mg/kg) CPF |
| GSM246132 |
Exp A_1, 1mg/kg CPF |
| GSM246133 |
Exp A_2, 1mg/kg CPF |
| GSM246134 |
Exp A_3, 1mg/kg CPF |
| GSM246135 |
Exp A_4, 1mg/kg CPF |
| GSM246136 |
Exp A_1, 10mg/kg CPF |
| GSM246137 |
Exp A_2, 10mg/kg CPF |
| GSM246138 |
Exp A_3, 10mg/kg CPF |
| GSM246139 |
Exp A_4, 10mg/kg CPF |
| GSM246140 |
Exp A_5, 10mg/kg CPF |
| GSM246141 |
Exp A_1, 50mg/kg CPF |
| GSM246142 |
Exp A_2, 50mg/kg CPF |
| GSM246143 |
Exp A_3, 50mg/kg CPF |
| GSM246144 |
Exp A_4, 50mg/kg CPF |
| GSM246145 |
Exp B_1, control (0mg/kg) CPF |
| GSM246146 |
Exp B_2, control (0mg/kg) CPF |
| GSM246147 |
Exp B_3, control (0mg/kg) CPF |
| GSM246148 |
Exp B_4, control (0mg/kg) CPF |
| GSM246149 |
Exp B_1, 0.5mg/kg CPF |
| GSM246150 |
Exp B_2, 0.5mg/kg CPF |
| GSM246151 |
Exp B_3, 0.5mg/kg CPF |
| GSM246152 |
Exp B_4, 0.5mg/kg CPF |
| GSM246153 |
Exp B_1, 5mg/kg CPF |
| GSM246154 |
Exp B_2, 30mg/kg CPF |
| GSM246155 |
Exp B_3, 30mg/kg CPF |
| GSM246156 |
Exp B_4, 30mg/kg CPF |
| GSM246157 |
Exp C_1, control (0mg/kg) CPF, 1st repeat |
| GSM246158 |
Exp C_2, control (0mg/kg) CPF |
| GSM246159 |
Exp C_3, control (0mg/kg) CPF |
| GSM246160 |
Exp C_1, 1mg/kg CPF |
| GSM246161 |
Exp C_2, 1mg/kg CPF |
| GSM246162 |
Exp C_3, 1mg/kg CPF |
| GSM246163 |
Exp C_4, 1mg/kg CPF |
| GSM246164 |
Exp C_1, 5mg/kg CPF |
| GSM246165 |
Exp C_2, 5mg/kg CPF |
| GSM246166 |
Exp C_3, 5mg/kg CPF |
| GSM246167 |
Exp C_4, 5mg/kg CPF |
| GSM246168 |
Exp C_1, 10mg/kg CPF |
| GSM246169 |
Exp C_2, 10mg/kg CPF, 1st repeat |
| GSM246170 |
Exp C_3, 10mg/kg CPF, 1st repeat |
| GSM246171 |
Exp C_4, 10mg/kg CPF |
| GSM246172 |
Exp C_1, 30mg/kg CPF |
| GSM246173 |
Exp C_2, 30mg/kg CPF |
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| Relations |
| BioProject |
PRJNA103677 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE9751_RAW.tar |
76.1 Mb |
(http)(custom) |
TAR (of CEL) |
| Processed data included within Sample table |
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