|
| Status |
Public on Dec 31, 2020 |
| Title |
PDAC_serum [M021] |
| Sample type |
protein |
| |
|
| Source name |
Serum
|
| Organism |
Homo sapiens |
| Characteristics |
tumor type: Pancreatic ductal adenocarcinoma
Sex: Female
age (in years): 64
|
| Growth protocol |
Serial blood samples were collected from the patients followed for advanced PDAC; and prior to surgery, and during postoperative standard follow up for patients with resectable PDAC. The collected blood was stored in -80⁰C until further use.
|
| Extracted molecule |
protein |
| Extraction protocol |
Blood was collected in the clinic during pre-surgical or pre-chemotherapy visits. Blood was collected in EDTA tubes, centrifuged, aliquoted, and stored first at -20C then at -80C until assay.
|
| Label |
n/a
|
| Label protocol |
not provided
|
| |
|
| Hybridization protocol |
not provided
|
| Scan protocol |
not provided
|
| Description |
SOMAscan human proteomic assay [SOMAscan Assay 1.3k]
|
| Data processing |
Sample data was first normalized to remove hybridization variation within a run followed by median normalization across all samples to remove all other assay biases within the run and finally calibrated to remove assay differences between runs. After all the preprocessing steps, quantile normalization was performed across all samples for proteins which will be used for downstream analyses.
|
| |
|
| Submission date |
Sep 05, 2018 |
| Last update date |
Dec 31, 2020 |
| Contact name |
Teresa Zimmers |
| E-mail(s) |
zimmerst@iu.edu
|
| Organization name |
Indiana University
|
| Department |
Surgery
|
| Lab |
Cachexia Lab
|
| Street address |
980 W. Walnut Street, R3-C518
|
| City |
Indianapolis |
| State/province |
IN |
| ZIP/Postal code |
46202 |
| Country |
USA |
| |
|
| Platform ID |
GPL23119 |
| Series (1) |
| GSE119483 |
Identification of circulating protein biomarkers for pancreatic cancer cachexia |
|
