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Sample GSM3964065 Query DataSets for GSM3964065
Status Public on Dec 31, 2022
Title M4-22, MOLM13.1uM.GSK862.d4.n2.n2
Sample type RNA
 
Source name MOLM13, GSK3484862, 1 µM
Organism Homo sapiens
Characteristics cell line: MOLM13
cell type: AML
Treatment protocol Cells were plated 24 hours before treatment with 0.1% DMSO, 1 µM GSK3484862, then grown for 96 hours before collection.
Growth protocol Cell lines were obtained from the American Type Culture Collection, the Deutsche Sammlung von Mikroorganismen und Zellbulturen, or AddexBio and maintained in the recommended cell culture media at 37°C in 5% CO2.
Extracted molecule total RNA
Extraction protocol RNA was isolated, labeled, and hybridized to Affymetrix GeneChip® Human Genome U133 Plus 2.0 arrays at Q2 Solutions.
Label biotin
Label protocol Not provided
 
Hybridization protocol Not provided
Scan protocol Not provided
Data processing Differential gene expression analysis was performed using limma with default settings for priors and other parameters on human genome U133 Plus 2.0 Affymetrix microarray .CEL files. Expression changes with adjusted p-values < 0.05 and absolute log2 fold change > 1 were considered significant.
 
Submission date Jul 23, 2019
Last update date Dec 31, 2022
Contact name Shawn W Foley
E-mail(s) shawn.w.foley@gsk.com
Organization name GlaxoSmithKline
Department Oncology
Street address 1250 S. Collegeville Rd
City Collegeville
State/province PA
ZIP/Postal code 19426
Country USA
 
Platform ID GPL570
Series (1)
GSE134716 Expression array of DNMT1 inhibitor treated AML cell lines

Data table header descriptions
ID_REF
VALUE Limma normalized signal intensity

Data table
ID_REF VALUE
1053_at 11.56157957
117_at 3.211038716
1294_at 6.636407924
1405_i_at 11.78682238
1438_at 2.14250705
1487_at 9.969105161
1552256_a_at 10.70577088
1552257_a_at 11.36459645
1552263_at 10.35733237
1552264_a_at 10.69379091
1552272_a_at 3.713853469
1552274_at 12.17213393
1552275_s_at 11.80517432
1552276_a_at 4.323914089
1552277_a_at 8.79762488
1552279_a_at 4.67055962
1552286_at 7.02941311
1552287_s_at 10.609706
1552288_at 2.96186994
1552291_at 8.759374459

Total number of rows: 27306

Table truncated, full table size 606 Kbytes.




Supplementary file Size Download File type/resource
GSM3964065_EA15172_603441_HG-U133_PLUS_2_M4-22.CEL.gz 5.2 Mb (ftp)(http) CEL
Processed data included within Sample table

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