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Sample GSM4710631 Query DataSets for GSM4710631
Status Public on May 31, 2021
Title Mdmx C462A no treatment rep1
Sample type RNA
 
Source name MEFs
Organism Mus musculus
Characteristics cell type: MEFs
genotype: Mdmx C462A
Treatment protocol Contained within publication; detailed protocols are available upon request
Growth protocol Contained within publication; detailed protocols are available upon request
Extracted molecule total RNA
Extraction protocol Contained within publication; detailed protocols are available upon request
Label biotin
Label protocol Contained within publication; detailed protocols are available upon request
 
Hybridization protocol Contained within publication; detailed protocols are available upon request
Scan protocol Contained within publication; detailed protocols are available upon request
Data processing The resultant dataset from the GeneChip™ Mouse Gene 2.0 array was performed in the Transcriptome Analysis Console (v4.0). This software was used for the creation of scatterplots, volcano plots, and hierarchical clustering. From these plots, the threshold for log fold change in gene expression was set at ± 2.0, with statistical significance cutoffs at or below a p-value of 0.05. Using these differentially expressed genes, the software MetaCore+MetaDrug™ (v20.2; build 70100) was used to perform pathway enrichment (PE) as well as gene ontology (GO) analyses (all p-values used were ≤ 0.05). Microsoft Excel was used to transform these results into 1/FDR (false discovery rate) as well as to create the combined figure.
 
Submission date Aug 04, 2020
Last update date May 31, 2021
Contact name Zhi-Min Yuan
Organization name Harvard University
Department Environmental Sciences
Street address 677 Huntington Ave.
City Boston
State/province Massachusetts
ZIP/Postal code 02115
Country USA
 
Platform ID GPL16570
Series (2)
GSE155694 Microarray of MDMX C462A and wildtype mice treated with acetaminophen
GSE155696 Hepatic p53 protein level governs liver s sensitivity to drug-induced liver injury

Supplementary file Size Download File type/resource
GSM4710631_ZY_C8_MN1.CEL.gz 8.4 Mb (ftp)(http) CEL
Processed data are available on Series record

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