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    Dlg4 discs large MAGUK scaffold protein 4 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 29495, updated on 2-Nov-2024

    Summary

    Official Symbol
    Dlg4provided by RGD
    Official Full Name
    discs large MAGUK scaffold protein 4provided by RGD
    Primary source
    RGD:68424
    See related
    EnsemblRapid:ENSRNOG00000018526 AllianceGenome:RGD:68424
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Dlgh4; PSD95; Sap90
    Summary
    Enables several functions, including PDZ domain binding activity; enzyme binding activity; and signaling receptor binding activity. A structural constituent of postsynaptic density. Involved in several processes, including modulation of chemical synaptic transmission; positive regulation of cellular component organization; and postsynapse organization. Located in several cellular components, including dendrite; juxtaparanode region of axon; and postsynaptic membrane. Part of voltage-gated potassium channel complex. Is active in glutamatergic synapse and postsynaptic density membrane. Biomarker of Parkinson's disease and temporal lobe epilepsy. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder. Orthologous to human DLG4 (discs large MAGUK scaffold protein 4). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Brain (RPKM 195.0), Adrenal (RPKM 29.1) and 7 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Dlg4 in Genome Data Viewer
    Location:
    10q24
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (55239397..55267780)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (54740700..54769097)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (56625845..56655543)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene dishevelled segment polarity protein 2 Neighboring gene acyl-CoA dehydrogenase, very long chain Neighboring gene microRNA 324 Neighboring gene asialoglycoprotein receptor 1 Neighboring gene transfer RNA threonine (anticodon AGU) 28

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables D1 dopamine receptor binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables P2Y1 nucleotide receptor binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables PDZ domain binding IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    enables PDZ domain binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables acetylcholine receptor binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables beta-1 adrenergic receptor binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables beta-2 adrenergic receptor binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables frizzled binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables glutamate receptor binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables ionotropic glutamate receptor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables ionotropic glutamate receptor binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables ionotropic glutamate receptor binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables ionotropic glutamate receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables kinase binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables kinase binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables kinesin binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables neuroligin family protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein kinase binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein kinase binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein phosphatase binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein-containing complex binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables scaffold protein binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables scaffold protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables scaffold protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables scaffold protein binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables signaling receptor binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables structural constituent of postsynaptic density IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables structural constituent of postsynaptic density IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in AMPA glutamate receptor clustering IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in AMPA glutamate receptor clustering IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in NMDA selective glutamate receptor signaling pathway IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in cell-cell adhesion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in cellular response to potassium ion IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in cellular response to potassium ion ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cerebral cortex development IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in chemical synaptic transmission IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in chemical synaptic transmission IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in dendritic spine morphogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in dendritic spine morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in dendritic spine morphogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in dendritic spine organization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in establishment of protein localization IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in establishment of protein localization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in establishment of protein localization ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in establishment or maintenance of epithelial cell apical/basal polarity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in locomotory exploration behavior IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in locomotory exploration behavior ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in locomotory exploration behavior ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in maintenance of postsynaptic density structure IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in negative regulation of receptor internalization IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in nervous system development IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in neuromuscular process controlling balance IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in neuromuscular process controlling balance ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in neuromuscular process controlling balance ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in neuronal ion channel clustering TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in neurotransmitter receptor localization to postsynaptic specialization membrane IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in neurotransmitter receptor localization to postsynaptic specialization membrane ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of AMPA glutamate receptor clustering IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of cytosolic calcium ion concentration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of dendrite morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of excitatory postsynaptic potential IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in positive regulation of excitatory postsynaptic potential IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of neuron projection arborization IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in positive regulation of synapse assembly IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of synaptic transmission IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in postsynaptic neurotransmitter receptor diffusion trapping IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in protein localization to synapse IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in protein localization to synapse IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within protein localization to synapse ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein localization to synapse ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein-containing complex assembly IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in protein-containing complex assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein-containing complex assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in receptor localization to synapse IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in regulation of NMDA receptor activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in regulation of grooming behavior IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of grooming behavior ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of grooming behavior ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in regulation of long-term neuronal synaptic plasticity IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within regulation of long-term neuronal synaptic plasticity ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of long-term neuronal synaptic plasticity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in regulation of neuronal synaptic plasticity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in social behavior IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in social behavior ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in social behavior ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in synaptic vesicle maturation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within synaptic vesicle maturation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in synaptic vesicle maturation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in vocalization behavior IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in vocalization behavior ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in vocalization behavior ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    part_of AMPA glutamate receptor complex IEA
    Inferred from Electronic Annotation
    more info
     
    part_of AMPA glutamate receptor complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of AMPA glutamate receptor complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in basolateral plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cell junction ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cell junction ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in cell periphery ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cell-cell junction IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cerebellar mossy fiber IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cerebellar mossy fiber ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cortical cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cortical cytoskeleton ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in cytosol TAS
    Traceable Author Statement
    more info
     
    located_in dendrite IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in dendrite ISO
    Inferred from Sequence Orthology
    more info
     
    located_in dendrite cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in dendritic branch IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in dendritic spine IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in dendritic spine IEA
    Inferred from Electronic Annotation
    more info
     
    located_in dendritic spine ISO
    Inferred from Sequence Orthology
    more info
     
    located_in dendritic spine ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    located_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    located_in endoplasmic reticulum ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in excitatory synapse IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in excitatory synapse IEA
    Inferred from Electronic Annotation
    more info
     
    located_in excitatory synapse ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in glutamatergic synapse IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in glutamatergic synapse IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in glutamatergic synapse IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    is_active_in glutamatergic synapse ISO
    Inferred from Sequence Orthology
    more info
     
    located_in glutamatergic synapse ISO
    Inferred from Sequence Orthology
    more info
     
    located_in juxtaparanode region of axon IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in juxtaparanode region of axon IEA
    Inferred from Electronic Annotation
    more info
     
    located_in juxtaparanode region of axon ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in membrane ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in neuromuscular junction IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in neuromuscular junction IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in neuron projection IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in neuron projection IEA
    Inferred from Electronic Annotation
    more info
     
    located_in neuron projection terminus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in neuron projection terminus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in neuron projection terminus ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in neuron spine ISO
    Inferred from Sequence Orthology
    more info
     
    located_in neuron spine ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane TAS
    Traceable Author Statement
    more info
     
    located_in postsynapse ISO
    Inferred from Sequence Orthology
    more info
     
    located_in postsynaptic density IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in postsynaptic density IEA
    Inferred from Electronic Annotation
    more info
     
    located_in postsynaptic density ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in postsynaptic density membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in postsynaptic density membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in postsynaptic density membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in postsynaptic membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in postsynaptic membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in postsynaptic membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in proximal dendrite IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in synapse IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in synapse IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    located_in synapse ISO
    Inferred from Sequence Orthology
    more info
     
    located_in synaptic membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in synaptic membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in synaptic vesicle IEA
    Inferred from Electronic Annotation
    more info
     
    located_in synaptic vesicle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in synaptic vesicle ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    part_of voltage-gated potassium channel complex IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    disks large homolog 4
    Names
    PSD-95
    SAP-90
    discs, large homolog 4
    postsynaptic density protein 95
    synapse-associated protein 90
    synapse-associated protein SAP90

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_019621.2NP_062567.1  disks large homolog 4

      See identical proteins and their annotated locations for NP_062567.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000010
      UniProtKB/Swiss-Prot
      P31016, P97631
      UniProtKB/TrEMBL
      A0A0G2K7F5
      Related
      ENSRNOP00000079351.2, ENSRNOT00000095923.2
      Conserved Domains (7) summary
      cd12030
      Location:430495
      SH3_DLG4; Src Homology 3 domain of Disks Large homolog 4
      smart00072
      Location:544710
      GuKc; Guanylate kinase homologues
      smart00228
      Location:310394
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam00595
      Location:65149
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam00625
      Location:533711
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:245312
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:1064
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      55239397..55267780
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006246687.5XP_006246749.1  disks large homolog 4 isoform X3

      UniProtKB/TrEMBL
      A0A0G2K7F5
      Conserved Domains (6) summary
      cd12030
      Location:427492
      SH3_DLG4; Src Homology 3 domain of Disks Large homolog 4
      smart00228
      Location:307391
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam00595
      Location:62146
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam00625
      Location:530708
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:242309
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:1061
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
    2. XM_039085767.2XP_038941695.1  disks large homolog 4 isoform X2

      UniProtKB/TrEMBL
      A0A0G2K7F5
      Related
      ENSRNOP00000080177.2, ENSRNOT00000096075.2
      Conserved Domains (6) summary
      cd12030
      Location:422487
      SH3_DLG4; Src Homology 3 domain of Disks Large homolog 4
      smart00228
      Location:302386
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam00595
      Location:57141
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam00625
      Location:525703
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:237304
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:656
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
    3. XM_008767809.4XP_008766031.2  disks large homolog 4 isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZMM3
      Conserved Domains (5) summary
      cd12030
      Location:370435
      SH3_DLG4; Src Homology 3 domain of Disks Large homolog 4
      smart00228
      Location:250334
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam00595
      Location:589
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam00625
      Location:473651
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:185252
      PDZ_assoc; PDZ-associated domain of NMDA receptors
    4. XM_039085766.2XP_038941694.1  disks large homolog 4 isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZMM3
      Conserved Domains (5) summary
      cd12030
      Location:370435
      SH3_DLG4; Src Homology 3 domain of Disks Large homolog 4
      smart00228
      Location:250334
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam00595
      Location:589
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam00625
      Location:473651
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:185252
      PDZ_assoc; PDZ-associated domain of NMDA receptors
    5. XM_039085768.1XP_038941696.1  disks large homolog 4 isoform X4

      UniProtKB/TrEMBL
      A0A0G2K7F5
      Related
      ENSRNOP00000080495.2, ENSRNOT00000099685.2

    RNA

    1. XR_005489771.2 RNA Sequence

      Related
      ENSRNOT00000089108.3