GRN-related frontotemporal lobar degeneration with Tdp43 inclusions
- Synonyms
- Dementia, hereditary dysphasic disinhibition; FRONTOTEMPORAL DEMENTIA WITH TDP43 INCLUSIONS, GRN-RELATED; FRONTOTEMPORAL LOBAR DEGENERATION WITH UBIQUITIN-POSITIVE INCLUSIONS; FTLD-TDP, GRN-RELATED; Frontotemporal dementia, ubiquitin-positive; GRN-Related Frontotemporal Dementia
Summary
Excerpted from the GeneReview:- Full text of GeneReview (by section):
- Summary
- Diagnosis
- Clinical Characteristics
- Genetically Related (Allelic) Disorders
- Differential Diagnosis
- Management
- Genetic Counseling
- Resources
- Molecular Genetics
- Chapter Notes
- References
- Authors:
- Ging-Yuek Robin Hsiung
- Howard H Feldman
- view full author information
Available tests
Clinical tests (55 available)
Clinical features
Help- Abnormality of the nervous system
- Agitation
Agitation
- MedGen UID: 88447
- Concept ID: C0085631
- Finding: Sign or Symptom
Abnormality of the nervous system
- Amplification of sexual behavior
Amplification of sexual behavior
- MedGen UID: 1853285
- Concept ID: C5873000
- Finding: Individual Behavior
Abnormality of the nervous system
- Apathy
Apathy
- MedGen UID: 39083
- Concept ID: C0085632
- Finding: Mental or Behavioral Dysfunction
Abnormality of the nervous system
- Aphasia
Aphasia
- MedGen UID: 8159
- Concept ID: C0003537
- Finding: Mental or Behavioral Dysfunction
Abnormality of the nervous system
- Apraxia
Apraxia
- MedGen UID: 8166
- Concept ID: C0003635
- Finding: Mental or Behavioral Dysfunction
Abnormality of the nervous system
- Cerebral cortical atrophy
Cerebral cortical atrophy
- MedGen UID: 1646740
- Concept ID: C4551583
- Finding: Disease or Syndrome
Abnormality of the nervous system
- Frontotemporal dementia
Frontotemporal dementia
- MedGen UID: 83266
- Concept ID: C0338451
- Finding: Disease or Syndrome
Abnormality of the nervous system
- Gliosis
Gliosis
- MedGen UID: 4899
- Concept ID: C0017639
- Finding: Pathologic Function
Abnormality of the nervous system
- Hallucinations
Hallucinations
- MedGen UID: 6709
- Concept ID: C0018524
- Finding: Mental or Behavioral Dysfunction
Abnormality of the nervous system
- Hyperorality
Hyperorality
- MedGen UID: 325386
- Concept ID: C1838320
- Finding: Finding
Abnormality of the nervous system
- Impulse control disorder
Impulse control disorder
- MedGen UID: 5769
- Concept ID: C0021122
- Finding: Mental or Behavioral Dysfunction
Abnormality of the nervous system
- Lateral ventricle dilatation
Lateral ventricle dilatation
- MedGen UID: 383904
- Concept ID: C1856409
- Finding: Pathologic Function
Abnormality of the nervous system
- Lewy bodies
Lewy bodies
- MedGen UID: 43126
- Concept ID: C0085200
- Finding: Cell Component
Abnormality of the nervous system
- Memory impairment
Memory impairment
- MedGen UID: 68579
- Concept ID: C0233794
- Finding: Mental or Behavioral Dysfunction
Abnormality of the nervous system
- Mutism
Mutism
- MedGen UID: 6476
- Concept ID: C0026884
- Finding: Disease or Syndrome
Abnormality of the nervous system
- Neurofibrillary tangles
Neurofibrillary tangles
- MedGen UID: 39273
- Concept ID: C0085400
- Finding: Finding
Abnormality of the nervous system
- Neuronal loss in central nervous system
Neuronal loss in central nervous system
- MedGen UID: 342515
- Concept ID: C1850496
- Finding: Finding
Abnormality of the nervous system
- Parkinsonian disorder
Parkinsonian disorder
- MedGen UID: 66079
- Concept ID: C0242422
- Finding: Disease or Syndrome
Abnormality of the nervous system
- Perseverative thought
Perseverative thought
- MedGen UID: 66686
- Concept ID: C0233651
- Finding: Mental or Behavioral Dysfunction
Abnormality of the nervous system
- Personality changes
Personality changes
- MedGen UID: 66817
- Concept ID: C0240735
- Finding: Mental or Behavioral Dysfunction
Abnormality of the nervous system
- Polyphagia
Polyphagia
- MedGen UID: 9369
- Concept ID: C0020505
- Finding: Finding
Abnormality of the nervous system
- Progressive language deterioration
Progressive language deterioration
- MedGen UID: 334494
- Concept ID: C1843793
- Finding: Finding
Abnormality of the nervous system
- Repetitive compulsive behavior
Repetitive compulsive behavior
- MedGen UID: 409891
- Concept ID: C1969697
- Finding: Mental or Behavioral Dysfunction
Abnormality of the nervous system
- Agitation
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