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Allergic contact dermatitis

MedGen UID:
102474
•Concept ID:
C0162820
•
Disease or Syndrome
Synonyms: Allergic Contact Dermatitides; Allergic Contact Dermatitis; Allergic Eczematous Dermatitides; Allergic Eczematous Dermatitis; Contact Dermatitides, Allergic; Contact Dermatitis, Allergic; Dermatitides, Allergic Contact; Dermatitides, Allergic Eczematous; Dermatitis, Allergic Contact; Dermatitis, Allergic Eczematous; Dermatitis, Contact, Allergic; Eczematous Dermatitides, Allergic; Eczematous Dermatitis, Allergic
SNOMED CT: Allergic contact dermatitis (238575004); ACD - Allergic contact dermatitis (238575004)
 
Monarch Initiative: MONDO:0006525

Definition

An inflammatory skin condition caused by an immune response to direct contact between the skin and an allergen. It consists of a delayed type of allergic reaction at the affected site with resulting red, swollen, and blistered skin that may itch or leak. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAllergic contact dermatitis

Professional guidelines

PubMed

Stasis Dermatitis: An Overview of Its Clinical Presentation, Pathogenesis, and Management.
Yosipovitch G, Nedorost ST, Silverberg JI, Friedman AJ, Canosa JM, Cha A
Am J Clin Dermatol 2023 Mar;24(2):275-286. Epub 2023 Feb 17 doi: 10.1007/s40257-022-00753-5. PMID: 36800152Free PMC Article
Guidelines for diagnosis, prevention, and treatment of hand eczema.
Thyssen JP, Schuttelaar MLA, Alfonso JH, Andersen KE, Angelova-Fischer I, Arents BWM, Bauer A, Brans R, Cannavo A, Christoffers WA, Crépy MN, Elsner P, Fartasch M, Filon FL, Giménez-Arnau AM, Gonçalo M, Guzmán-Perera MG, Hamann CR, Hoetzenecker W, Johansen JD, John SM, Kunkeler ACM, Hadzavdic SL, Molin S, Nixon R, Oosterhaven JAF, Rustemeyer T, Serra-Baldrich E, Shah M, Simon D, Skudlik C, Spiewak R, Valiukevičienė S, Voorberg AN, Weisshaar E, Agner T
Contact Dermatitis 2022 May;86(5):357-378. Epub 2022 Mar 3 doi: 10.1111/cod.14035. PMID: 34971008
Contact Dermatitis: Classifications and Management.
Li Y, Li L
Clin Rev Allergy Immunol 2021 Dec;61(3):245-281. Epub 2021 Jul 15 doi: 10.1007/s12016-021-08875-0. PMID: 34264448

Recent clinical studies

Etiology

Role of Innate Immunity in Allergic Contact Dermatitis: An Update.
Yamaguchi HL, Yamaguchi Y, Peeva E
Int J Mol Sci 2023 Aug 19;24(16) doi: 10.3390/ijms241612975. PMID: 37629154Free PMC Article
Irritant Contact Dermatitis.
Bains SN, Nash P, Fonacier L
Clin Rev Allergy Immunol 2019 Feb;56(1):99-109. doi: 10.1007/s12016-018-8713-0. PMID: 30293200
Patch Testing Pearls.
Uyesugi BA, Sheehan MP
Clin Rev Allergy Immunol 2019 Feb;56(1):110-118. doi: 10.1007/s12016-018-8715-y. PMID: 30269296
Contact allergy: an update.
Ljubojević Hadžavdić S, Pustišek N, Žužul K, Švigir A
G Ital Dermatol Venereol 2018 Jun;153(3):419-428. Epub 2017 Dec 1 doi: 10.23736/S0392-0488.17.05844-8. PMID: 29199804
Alkyl Glucosides.
Alfalah M, Loranger C, Sasseville D
Dermatitis 2017 Jan/Feb;28(1):3-4. doi: 10.1097/DER.0000000000000234. PMID: 27775973

Diagnosis

Allergic Contact Dermatitis.
Edwards TM, Usatine RP, Heath CR
Cutis 2023 Oct;112(4):195-197. doi: 10.12788/cutis.0868. PMID: 37988316
Allergic contact dermatitis.
Edwards TM, Usatine RP, Heath CR
J Fam Pract 2023 Oct;72(8):350-355. doi: 10.12788/jfp.0678. PMID: 37862625
Pediatric Allergic Contact Dermatitis.
Brown C, Yu J
Immunol Allergy Clin North Am 2021 Aug;41(3):393-408. Epub 2021 Jun 5 doi: 10.1016/j.iac.2021.04.004. PMID: 34225896
Allergic Contact Dermatitis.
Adler BL, DeLeo VA
JAMA Dermatol 2021 Mar 1;157(3):364. doi: 10.1001/jamadermatol.2020.5639. PMID: 33502447
Allergic Contact Dermatitis.
Nassau S, Fonacier L
Med Clin North Am 2020 Jan;104(1):61-76. Epub 2019 Oct 28 doi: 10.1016/j.mcna.2019.08.012. PMID: 31757238

Therapy

Allergic Contact Dermatitis in Pediatric Practice.
Hon KL, Leung AKC, Cheng JWCH, Luk DCK, Leung ASY, Koh MJA
Curr Pediatr Rev 2024;20(4):478-488. doi: 10.2174/1573396320666230626122135. PMID: 37365784
Allergic Contact Dermatitis of the Vulva.
Woodruff CM, Trivedi MK, Botto N, Kornik R
Dermatitis 2018 Sep/Oct;29(5):233-243. doi: 10.1097/DER.0000000000000339. PMID: 30179968
Allergic contact dermatitis from ophthalmics.
Zheng Y, Chaudhari PR, Maibach HI
Cutan Ocul Toxicol 2017 Dec;36(4):317-320. Epub 2017 Mar 6 doi: 10.1080/15569527.2017.1295251. PMID: 28632093
Wound-Related Allergic/Irritant Contact Dermatitis.
Alavi A, Sibbald RG, Ladizinski B, Saraiya A, Lee KC, Skotnicki-Grant S, Maibach H
Adv Skin Wound Care 2016 Jun;29(6):278-86. doi: 10.1097/01.ASW.0000482834.94375.1e. PMID: 27171256
Allergic contact dermatitis to cosmetics.
Park ME, Zippin JH
Dermatol Clin 2014 Jan;32(1):1-11. doi: 10.1016/j.det.2013.09.006. PMID: 24267417

Prognosis

Tattoos: Very Popular, Not So Innocent.
Hermida MD, Cabrera HN
Skinmed 2017;15(1):37-42. Epub 2017 Feb 1 PMID: 28270308
Allergic contact dermatitis: Patient diagnosis and evaluation.
Mowad CM, Anderson B, Scheinman P, Pootongkam S, Nedorost S, Brod B
J Am Acad Dermatol 2016 Jun;74(6):1029-40. doi: 10.1016/j.jaad.2015.02.1139. PMID: 27185421
Skin diseases in musicians.
Crépy MN
Eur J Dermatol 2015 Sep-Oct;25(5):375-83. doi: 10.1684/ejd.2015.2559. PMID: 25905552
Diagnosis and management of contact dermatitis.
Usatine RP, Riojas M
Am Fam Physician 2010 Aug 1;82(3):249-55. PMID: 20672788
Occupational dermatoses.
Beltrani VS
Curr Opin Allergy Clin Immunol 2003 Apr;3(2):115-23. doi: 10.1097/00130832-200304000-00005. PMID: 12750608

Clinical prediction guides

Allergic Contact Dermatitis in Pediatric Practice.
Hon KL, Leung AKC, Cheng JWCH, Luk DCK, Leung ASY, Koh MJA
Curr Pediatr Rev 2024;20(4):478-488. doi: 10.2174/1573396320666230626122135. PMID: 37365784
Allergic contact dermatitis from dyes used in the temple of spectacles.
Ahrensbøll-Friis U, Simonsen AB, Dahlin J, Isaksson M, Zachariae C, Johansen JD
Contact Dermatitis 2022 Jan;86(1):25-28. Epub 2021 Oct 25 doi: 10.1111/cod.13989. PMID: 34655078
Conctact dermatitis: some important topics.
Pigatto PD
Eur Ann Allergy Clin Immunol 2015 Nov;47(6):188-91. PMID: 26549335
Tefillin dermatitis.
Trattner A, David M
J Am Acad Dermatol 2005 May;52(5):831-3. doi: 10.1016/j.jaad.2004.12.042. PMID: 15858473
Allergic contact dermatitis.
Kimber I, Basketter DA, Gerberick GF, Dearman RJ
Int Immunopharmacol 2002 Feb;2(2-3):201-11. doi: 10.1016/s1567-5769(01)00173-4. PMID: 11811925

Recent systematic reviews

Nipple eczema: A systematic review and practical recommendations.
Reynaert V, Gutermuth J, Wollenberg A
J Eur Acad Dermatol Venereol 2023 Jun;37(6):1149-1159. Epub 2023 Feb 16 doi: 10.1111/jdv.18920. PMID: 36695082
Side effects of gel nail polish: A systematic review.
Litaiem N, Baklouti M, Zeglaoui F
Clin Dermatol 2022 Nov-Dec;40(6):706-715. Epub 2022 Jul 28 doi: 10.1016/j.clindermatol.2022.07.008. PMID: 35907576
Hand hygiene and hand eczema: A systematic review and meta-analysis.
Loh EW, Yew YW
Contact Dermatitis 2022 Oct;87(4):303-314. Epub 2022 May 2 doi: 10.1111/cod.14133. PMID: 35460528Free PMC Article
Dupilumab ocular side effects in patients with atopic dermatitis: a systematic review.
Neagu N, Dianzani C, Avallone G, Dell'Aquila C, Morariu SH, Zalaudek I, Conforti C
J Eur Acad Dermatol Venereol 2022 Jun;36(6):820-835. Epub 2022 Feb 17 doi: 10.1111/jdv.17981. PMID: 35122335
Facial and neck erythema associated with dupilumab treatment: A systematic review.
Jo CE, Finstad A, Georgakopoulos JR, Piguet V, Yeung J, Drucker AM
J Am Acad Dermatol 2021 May;84(5):1339-1347. Epub 2021 Jan 8 doi: 10.1016/j.jaad.2021.01.012. PMID: 33428978

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