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Eccrine acrospiroma

MedGen UID:
104915
•Concept ID:
C0206671
•
Neoplastic Process
Synonyms: Acrospiroma, Eccrine; Eccrine Acrospiroma; Eccrine Acrospiromas; Eccrine Spiradenoma; Eccrine Spiradenomas; Spiradenoma, Eccrine; Spiradenomas, Eccrine
SNOMED CT: Eccrine acrospiroma (81143000); Eccrine hidradenoma (400099008); Apocrine nodular hidradenoma (400099008); Eccrine hidradenoma of skin (400099008); Solid-cystic hidradenoma (400099008); Eccrine nodular hidradenoma (400099008); Eccrine acrospiroma (400099008); Nodular hidradenoma (81143000); Nodular hidradenoma (253020008)
 
Monarch Initiative: MONDO:0006738

Definition

A benign epithelial neoplasm arising from the sweat glands. It presents as a nodular lesion usually in the scalp, trunk, and proximal extremities. It is characterized by a nodular growth pattern. Complete excision is curative. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVEccrine acrospiroma

Professional guidelines

PubMed

Challenges in diagnosis and management of a spiradenocarcinoma: a comprehensive literature review.
Wagner K, Jassal K, Lee JC, Ban EJ, Cameron R, Serpell J
ANZ J Surg 2021 Oct;91(10):1996-2001. Epub 2021 Feb 1 doi: 10.1111/ans.16626. PMID: 33522696
Evaluation and management of the patient with multiple syringomas: A systematic review of the literature.
Williams K, Shinkai K
J Am Acad Dermatol 2016 Jun;74(6):1234-1240.e9. Epub 2016 Feb 3 doi: 10.1016/j.jaad.2015.12.006. PMID: 26850654
Differential and exclusive diagnosis of diseases that resemble keloids and hypertrophic scars.
Ogawa R, Akaishi S, Hyakusoku H
Ann Plast Surg 2009 Jun;62(6):660-4. doi: 10.1097/SAP.0b013e31817e9d67. PMID: 19461281

Recent clinical studies

Etiology

Adnexal skin tumors in Zaria, Nigeria.
Samaila MO
Ann Afr Med 2008 Mar;7(1):6-10. doi: 10.4103/1596-3519.55691. PMID: 18702242
Spectrum of cutaneous appendage tumors at Aga Khan University Hospital.
Yaqoob N, Ahmad Z, Muzaffar S, Gill MS, Soomro IN, Hasan SH
J Pak Med Assoc 2003 Sep;53(9):427-31. PMID: 14620320
Papillary transitional cell carcinoma of the breast: a report of five cases with distinction from eccrine acrospiroma.
Mooney EE, Tavassoli FA
Mod Pathol 1999 Mar;12(3):287-94. PMID: 10102614
Eccrine acrospiroma in a young African male: case report.
Nmadu PT
East Afr Med J 1995 Sep;72(9):613-4. PMID: 7498053
Clear cell eccrine carcinomas of the skin. A clinicopathologic study of nine patients.
Wong TY, Suster S, Nogita T, Duncan LM, Dickersin RG, Mihm MC Jr
Cancer 1994 Mar 15;73(6):1631-43. doi: 10.1002/1097-0142(19940315)73:6<1631::aid-cncr2820730615>3.0.co;2-7. PMID: 7512435

Diagnosis

Recurrent Eccrine Acrospiroma of the Parotid Region: A Case Report.
Gupta V, Mishra UP, Behera G
JNMA J Nepal Med Assoc 2021 Dec 11;59(244):1307-1309. doi: 10.31729/jnma.5702. PMID: 35199797Free PMC Article
Dermoscopy of eccrine acrospiroma masquerading as nodular malignant melanoma.
Gatti A, di Meo N, Trevisan G
Acta Dermatovenerol Alp Pannonica Adriat 2010 Dec;19(4):23-5. PMID: 21390477
Assessment of cellular proliferation of eccrine acrospiromas and eccrine sweat gland carcinomas by AgNOR counting and immunohistochemical demonstration of proliferating cell nuclear antigen (PCNA) and Ki-67.
Ansai S, Koseki S, Hozumi Y, Kondo S
Clin Exp Dermatol 1995 Jan;20(1):27-34. doi: 10.1111/j.1365-2230.1995.tb01278.x. PMID: 7671392
Stump the experts. Eccrine acrospiroma.
Schleicher SM, Milstein HJ, Lim SJ
J Dermatol Surg Oncol 1989 Dec;15(12):1250, 1297. doi: 10.1111/j.1524-4725.1989.tb03140.x. PMID: 2556463
Eccrine acrospiroma. A clinicopathologic study.
Johnson BL Jr, Helwig EB
Cancer 1969 Mar;23(3):641-57. doi: 10.1002/1097-0142(196903)23:3<641::aid-cncr2820230318>3.0.co;2-b. PMID: 5775301

Prognosis

Assessment of cellular proliferation of eccrine acrospiromas and eccrine sweat gland carcinomas by AgNOR counting and immunohistochemical demonstration of proliferating cell nuclear antigen (PCNA) and Ki-67.
Ansai S, Koseki S, Hozumi Y, Kondo S
Clin Exp Dermatol 1995 Jan;20(1):27-34. doi: 10.1111/j.1365-2230.1995.tb01278.x. PMID: 7671392
Eccrine acrospiroma in a young African male: case report.
Nmadu PT
East Afr Med J 1995 Sep;72(9):613-4. PMID: 7498053
Eccrine adenocarcinoma--report of a case, treatment with Mohs surgery.
Dzubow LM, Grossman DJ, Johnson B
J Dermatol Surg Oncol 1986 Oct;12(10):1049-53. doi: 10.1111/j.1524-4725.1986.tb02082.x. PMID: 3760312

Clinical prediction guides

Assessment of cellular proliferation of eccrine acrospiromas and eccrine sweat gland carcinomas by AgNOR counting and immunohistochemical demonstration of proliferating cell nuclear antigen (PCNA) and Ki-67.
Ansai S, Koseki S, Hozumi Y, Kondo S
Clin Exp Dermatol 1995 Jan;20(1):27-34. doi: 10.1111/j.1365-2230.1995.tb01278.x. PMID: 7671392

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