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Adenoma

MedGen UID:
125
Concept ID:
C0001430
Neoplastic Process
Synonym: Adenomas
SNOMED CT: Benign adenomatous neoplasm (443416007); Benign adenomatous neoplasm (1187227004); Adenoma (1187375007); Adenoma (1187379001); Benign adenoma (1187379001)
 
Monarch Initiative: MONDO:0004972

Definition

A neoplasm arising from the epithelium. It may be encapsulated or non-encapsulated but non-invasive. The neoplastic epithelial cells may or may not display cellular atypia or dysplasia. In the gastrointestinal tract, when dysplasia becomes severe it is sometimes called carcinoma in situ. Representative examples are pituitary gland adenoma, follicular adenoma of the thyroid gland, and adenomas (or adenomatous polyps) of the gastrointestinal tract. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAdenoma

Professional guidelines

PubMed

Fassnacht M, Tsagarakis S, Terzolo M, Tabarin A, Sahdev A, Newell-Price J, Pelsma I, Marina L, Lorenz K, Bancos I, Arlt W, Dekkers OM
Eur J Endocrinol 2023 Jul 20;189(1):G1-G42. doi: 10.1093/ejendo/lvad066. PMID: 37318239
Reincke M, Bancos I, Mulatero P, Scholl UI, Stowasser M, Williams TA
Lancet Diabetes Endocrinol 2021 Dec;9(12):876-892. doi: 10.1016/S2213-8587(21)00210-2. PMID: 34798068
Reid JR, Wheeler SF
Am Fam Physician 2005 Aug 15;72(4):623-30. PMID: 16127951

Recent clinical studies

Etiology

Myers L, Ahn J
Clin Liver Dis 2020 Aug;24(3):389-403. Epub 2020 Jun 3 doi: 10.1016/j.cld.2020.04.013. PMID: 32620279
Gupta T, Chatterjee A
Neurol India 2020 May-Jun;68(Supplement):S113-S122. doi: 10.4103/0028-3886.287678. PMID: 32611901
Mete O, Lopes MB
Endocr Pathol 2017 Sep;28(3):228-243. doi: 10.1007/s12022-017-9498-z. PMID: 28766057
Bioulac-Sage P, Sempoux C, Balabaud C
Semin Diagn Pathol 2017 Mar;34(2):112-125. Epub 2016 Dec 20 doi: 10.1053/j.semdp.2016.12.007. PMID: 28131467
Lin J, Goldblum JR, Bennett AE, Bronner MP, Liu X
Am J Surg Pathol 2012 Feb;36(2):292-5. doi: 10.1097/PAS.0b013e318236e4d2. PMID: 22082602

Diagnosis

McCarthy M, Whaley RD, Erickson LA
Mayo Clin Proc 2022 Nov;97(11):2168-2169. doi: 10.1016/j.mayocp.2022.09.015. PMID: 36333022
Brownlee BP, Mann D, Glenn C, McKinney KA
Otolaryngol Clin North Am 2022 Apr;55(2):343-350. doi: 10.1016/j.otc.2021.12.015. PMID: 35365312
Peraza AJ, Wright J, Gómez R
J Craniomaxillofac Surg 2017 Oct;45(10):1754-1758. Epub 2017 Aug 3 doi: 10.1016/j.jcms.2017.07.020. PMID: 28890252
Cerdà Gabaroi D, Corominas Macías H, Reina Sanz D, Fíguls Poch R
Reumatol Clin 2013 Mar-Apr;9(2):128-9. Epub 2012 Apr 7 doi: 10.1016/j.reuma.2012.01.004. PMID: 22484062
Bruneton JN, Ballanger P, Ballanger R, Delorme G
Clin Radiol 1979 May;30(3):343-52. doi: 10.1016/s0009-9260(79)80100-2. PMID: 455910

Therapy

Xu H, Tang RSY, Lam TYT, Zhao G, Lau JYW, Liu Y, Wu Q, Rong L, Xu W, Li X, Wong SH, Cai S, Wang J, Liu G, Ma T, Liang X, Mak JWY, Xu H, Yuan P, Cao T, Li F, Ye Z, Shutian Z, Sung JJY
Clin Gastroenterol Hepatol 2023 Feb;21(2):337-346.e3. Epub 2022 Jul 19 doi: 10.1016/j.cgh.2022.07.006. PMID: 35863686
Yin J, Ngiam KY, Teo HH
J Med Internet Res 2021 Apr 22;23(4):e25759. doi: 10.2196/25759. PMID: 33885365Free PMC Article
Tołoczko-Iwaniuk N, Dziemiańczyk-Pakieła D, Nowaszewska BK, Celińska-Janowicz K, Miltyk W
Curr Drug Targets 2019;20(3):302-315. doi: 10.2174/1389450119666180803121737. PMID: 30073924
Hafner S, Zolk K, Radaelli F, Otte J, Rabenstein T, Zolk O
Cochrane Database Syst Rev 2015 May 26;2015(5):CD009863. doi: 10.1002/14651858.CD009863.pub2. PMID: 26011829Free PMC Article
Reid JR, Wheeler SF
Am Fam Physician 2005 Aug 15;72(4):623-30. PMID: 16127951

Prognosis

Hakami OA, Ahmed S, Karavitaki N
Best Pract Res Clin Endocrinol Metab 2021 Jan;35(1):101521. Epub 2021 Mar 15 doi: 10.1016/j.beem.2021.101521. PMID: 33766428
Daly AF, Beckers A
Endocrinol Metab Clin North Am 2020 Sep;49(3):347-355. Epub 2020 Jun 10 doi: 10.1016/j.ecl.2020.04.002. PMID: 32741475
Chin SO
Endocrinol Metab (Seoul) 2020 Jun;35(2):237-242. Epub 2020 Jun 24 doi: 10.3803/EnM.2020.35.2.237. PMID: 32615708Free PMC Article
Ben-Shlomo A, Cooper O
Pituitary 2018 Apr;21(2):183-193. doi: 10.1007/s11102-018-0864-8. PMID: 29344907
Brenner H, Kloor M, Pox CP
Lancet 2014 Apr 26;383(9927):1490-1502. Epub 2013 Nov 11 doi: 10.1016/S0140-6736(13)61649-9. PMID: 24225001

Clinical prediction guides

Dietrich CF, Tana C, Caraiani C, Dong Y
Expert Rev Gastroenterol Hepatol 2018 May;12(5):479-489. Epub 2018 Apr 24 doi: 10.1080/17474124.2018.1464389. PMID: 29658347
Cohen J, Grunwald D, Grossberg LB, Sawhney MS
J Clin Gastroenterol 2017 Oct;51(9):818-824. doi: 10.1097/MCG.0000000000000695. PMID: 27683963Free PMC Article
Kato M
World J Gastroenterol 2015 Nov 28;21(44):12513-8. doi: 10.3748/wjg.v21.i44.12513. PMID: 26640329Free PMC Article
Amin W, Parwani AV
Pathol Res Pract 2010 Oct 15;206(10):659-62. Epub 2010 Jul 8 doi: 10.1016/j.prp.2010.06.001. PMID: 20619548
McBiles M, Lambert AT, Cote MG, Kim SY
Semin Nucl Med 1995 Jul;25(3):221-34. doi: 10.1016/s0001-2998(95)80012-3. PMID: 7570042

Recent systematic reviews

Aneke-Nash C, Yoon G, Du M, Liang P
BMJ Open Gastroenterol 2021 Jun;8(1) doi: 10.1136/bmjgast-2021-000601. PMID: 34083227Free PMC Article
Peraza AJ, Wright J, Gómez R
J Craniomaxillofac Surg 2017 Oct;45(10):1754-1758. Epub 2017 Aug 3 doi: 10.1016/j.jcms.2017.07.020. PMID: 28890252
Bailie L, Loughrey MB, Coleman HG
Gastroenterology 2017 Jan;152(1):92-104. Epub 2016 Sep 14 doi: 10.1053/j.gastro.2016.09.003. PMID: 27639804
Knight J, Ratnasingham K
Int J Surg 2015 Jul;19:137-45. Epub 2015 May 6 doi: 10.1016/j.ijsu.2015.04.084. PMID: 25958295
Cooper O
Pituitary 2015 Apr;18(2):225-31. doi: 10.1007/s11102-014-0624-3. PMID: 25534889Free PMC Article

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