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Calcifying Cystic Odontogenic Tumor

MedGen UID:
104931
Concept ID:
C0206740
Neoplastic Process
Synonyms: Calcifying Odontogenic Cyst; Calcifying Odontogenic Cysts; Cyst, Calcifying Odontogenic; Cysts, Calcifying Odontogenic; Odontogenic Cyst, Calcifying; Odontogenic Cysts, Calcifying
SNOMED CT: Calcifying odontogenic cyst (75248003)

Definition

A benign, intraosseous or extraosseous cystic neoplasm arising from tooth-forming tissues. It is characterized by the presence of a cyst lined by an ameloblastoma-like epithelium and ghost cells formation. The ghost cells may undergo calcification. It is treated with enucleation. Few recurrences have been reported for intraosseous neoplasms whereas no recurrences have been reported for extraosseous neoplasms. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCalcifying Cystic Odontogenic Tumor

Professional guidelines

PubMed

Okura S, Igarashi C, Wakae-Morita S, Eda T, Ito H, Nakashima K, Sugisaki M, Ito Y, Kobayashi K
Oral Radiol 2022 Jan;38(1):99-104. Epub 2021 Apr 27 doi: 10.1007/s11282-021-00531-9. PMID: 33907948
Karagozoglu KH, Van Hagen JM, Baart JA, Van Der Waal I
Minerva Stomatol 2011 Jan-Feb;60(1-2):1-4. PMID: 21252844
Manor Y, Mardinger O, Katz J, Taicher S, Hirshberg A
Int J Oral Maxillofac Surg 2004 Apr;33(3):268-73. doi: 10.1006/ijom.2003.0508. PMID: 15287310

Recent clinical studies

Etiology

Muddana K, Maloth AK, Dorankula SPR, Kulkarni PG
Indian J Dent Res 2019 Jan-Feb;30(1):144-148. doi: 10.4103/ijdr.IJDR_105_17. PMID: 30900676
Manohar B, Baidya D, Shetty N, Mathur A, Makhijani B
J Exp Ther Oncol 2017 Nov;12(2):151-156. PMID: 29161784
Irani S, Foroughi F
J Contemp Dent Pract 2017 Aug 1;18(8):688-694. doi: 10.5005/jp-journals-10024-2108. PMID: 28816191
Guimarães DM, Antunes DM, Saturno JL, Massuda F, Paiva KB, Nunes FD
Acta Histochem 2015 Oct;117(8):667-74. Epub 2015 Nov 7 doi: 10.1016/j.acthis.2015.10.006. PMID: 26558991
Johnson NR, Savage NW, Kazoullis S, Batstone MD
Oral Surg Oral Med Oral Pathol Oral Radiol 2013 Apr;115(4):515-22. doi: 10.1016/j.oooo.2013.01.016. PMID: 23522645

Diagnosis

Manohar B, Baidya D, Shetty N, Mathur A, Makhijani B
J Exp Ther Oncol 2017 Nov;12(2):151-156. PMID: 29161784
Bilodeau EA, Collins BM
Surg Pathol Clin 2017 Mar;10(1):177-222. Epub 2016 Dec 29 doi: 10.1016/j.path.2016.10.006. PMID: 28153133
Sheikh J, Cohen MD, Ramer N, Payami A
J Oral Maxillofac Surg 2017 Apr;75(4):750-758. Epub 2016 Oct 26 doi: 10.1016/j.joms.2016.10.013. PMID: 27865804
de Santana Santos T, Frota R, de Souza Andrade ES, de Oliveira E Silva ED
J Craniofac Surg 2013 Mar;24(2):e134-6. doi: 10.1097/SCS.0b013e31827c7c0f. PMID: 23524811
Press SG
Curr Opin Otolaryngol Head Neck Surg 2008 Feb;16(1):47-54. doi: 10.1097/MOO.0b013e3282f419da. PMID: 18197022

Prognosis

Bilodeau EA, Collins BM
Surg Pathol Clin 2017 Mar;10(1):177-222. Epub 2016 Dec 29 doi: 10.1016/j.path.2016.10.006. PMID: 28153133
Masuda K, Kawano S, Yamaza H, Sakamoto T, Kiyoshima T, Nakamura S, Nonaka K
World J Surg Oncol 2015 Sep 17;13:277. doi: 10.1186/s12957-015-0697-0. PMID: 26376974Free PMC Article
Johnson NR, Savage NW, Kazoullis S, Batstone MD
Oral Surg Oral Med Oral Pathol Oral Radiol 2013 Apr;115(4):515-22. doi: 10.1016/j.oooo.2013.01.016. PMID: 23522645
Arashiyama T, Kodama Y, Kobayashi T, Hoshina H, Takagi R, Hayashi T, Cheng J, Saku T
Oral Surg Oral Med Oral Pathol Oral Radiol 2012 Sep;114(3):e35-40. Epub 2012 Jun 1 doi: 10.1016/j.oooo.2012.01.018. PMID: 22862988
Ribeiro AL, Nobre RM, Rocha GC, de Souza Lobato IH, de Melo Alves Junior S, Jaeger RG, de Jesus Viana Pinheiro J
J Oral Pathol Med 2011 Jul;40(6):516-9. Epub 2011 Mar 4 doi: 10.1111/j.1600-0714.2011.01025.x. PMID: 21371124

Clinical prediction guides

Mehngi R, Rajendra K, Bhagwat P, Hegde SS, Sah D, Rathod VS
J Contemp Dent Pract 2018 Oct 1;19(10):1288-1292. PMID: 30498188
da Costa NMM, de Siqueira AS, Ribeiro ALR, da Silva Kataoka MS, Jaeger RG, de Alves-Júnior SM, Smith AM, de Jesus Viana Pinheiro J
Clin Oral Investig 2018 Jan;22(1):141-149. Epub 2017 Feb 25 doi: 10.1007/s00784-017-2090-6. PMID: 28238093
Ribeiro Ribeiro AL, da Costa NM, de Siqueira AS, Brasil da Silva W, da Silva Kataoka MS, Jaeger RG, de Melo Alves-Junior S, Smith AM, de Jesus Viana Pinheiro J
Oral Surg Oral Med Oral Pathol Oral Radiol 2016 Oct;122(4):500-8. Epub 2016 Jun 22 doi: 10.1016/j.oooo.2016.06.004. PMID: 27554376
Kikuchi K, Ito S, Inoue H, González-Alva P, Miyazaki Y, Sakashita H, Yoshino A, Katayama Y, Terui T, Ide F, Kusama K
J Oral Sci 2012;54(2):165-75. doi: 10.2334/josnusd.54.165. PMID: 22790409
Ribeiro BF, Ferreira de Araújo CR, dos Santos BR, de Almeida Freitas R
Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2011 Nov;112(5):609-15. Epub 2011 Sep 8 doi: 10.1016/j.tripleo.2011.06.009. PMID: 21903428

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