Reduced muscle phosphoglycerate mutase activity

MedGen UID:: 1054611
•Concept ID:: CN376710
•: Finding

HPO:	HP:6000197

Definition

Activity of the enzyme Phosphoglycerate mutase (PGM) in muscle tissue is below the lower limit of normal. PGM is an enzyme that catalyzes step 8 of glycolysis (EC 5.4.2.11). [from HPO]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVReduced muscle phosphoglycerate mutase activity

Phenotypic abnormality
- Abnormality of metabolism/homeostasis
  - Abnormal enzyme concentration or activity
    - Abnormal tissue enzyme concentration or activity
      - Abnormal enzyme activity in muscle tissue
        Reduced muscle phosphoglycerate mutase activity

Recent clinical studies

Etiology

Inactivation of phosphoglycerate mutase and creatine kinase isoenzymes in human serum.

Durany N, Carreras J, Valentí M, Cámara J, Carreras J
Mol Pathol 2002 Aug;55(4):242-9. doi: 10.1136/mp.55.4.242. PMID: 12147715 Free PMC Article

See all (1)

Prognosis

Inactivation of phosphoglycerate mutase and creatine kinase isoenzymes in human serum.

Durany N, Carreras J, Valentí M, Cámara J, Carreras J
Mol Pathol 2002 Aug;55(4):242-9. doi: 10.1136/mp.55.4.242. PMID: 12147715 Free PMC Article

See all (1)

Clinical prediction guides

Paralysis of innervated cultured human muscle fibers affects enzymes differentially.

Martinuzzi A, Askanas V, Engel WK
J Neurochem 1990 Jan;54(1):223-9. doi: 10.1111/j.1471-4159.1990.tb13304.x. PMID: 2152794

See all (1)

MedGen

National Center for Biotechnology Information

Send to:

Reduced muscle phosphoglycerate mutase activity

Definition

Term Hierarchy

Recent clinical studies

Etiology

Prognosis

Clinical prediction guides

Supplemental Content

Table of contents

Clinical resources

Consumer resources

Reviews

Related information

Recent activity