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Nut food product allergy

MedGen UID:
108401
•Concept ID:
C0577620
•
Disease or Syndrome
Synonyms: Allergies, Nut; Allergies, Tree Nut; Allergy, Nut; Allergy, Tree Nut; Hypersensitivities, Nut; Hypersensitivities, Tree Nut; Hypersensitivity, Nut; Hypersensitivity, Tree Nut; Nut Allergies; Nut Allergy; Nut Hypersensitivities; Nut Hypersensitivities, Tree; Nut Hypersensitivity; Nut Hypersensitivity, Tree; Tree Nut Allergies; Tree Nut Allergy; Tree Nut Hypersensitivities; Tree Nut Hypersensitivity
SNOMED CT: Nut allergy (91934008); Allergy to nut (91934008)
 
HPO: HP:0410331

Definition

Hypersensitivity in form of an adverse immune reaction against nut food products. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVNut food product allergy

Professional guidelines

PubMed

Diagnosis and Management of Pollen Food Allergy Syndrome to Nuts.
Giovannini M, Skypala IJ, Caubet JC, Du Toit G, Nowak-Wegrzyn A
J Allergy Clin Immunol Pract 2024 Mar;12(3):599-604. Epub 2024 Jan 25 doi: 10.1016/j.jaip.2024.01.025. PMID: 38280450
Management of nut allergy in primary care.
Fong WCG, Walsh J, Fox AT, Marrs T
Br J Gen Pract 2018 Feb;68(667):98-99. doi: 10.3399/bjgp18X694817. PMID: 29371317Free PMC Article
Food Allergy: Common Causes, Diagnosis, and Treatment.
Patel BY, Volcheck GW
Mayo Clin Proc 2015 Oct;90(10):1411-9. doi: 10.1016/j.mayocp.2015.07.012. PMID: 26434966

Recent clinical studies

Etiology

Consumption of Nuts and Seeds and Health Outcomes Including Cardiovascular Disease, Diabetes and Metabolic Disease, Cancer, and Mortality: An Umbrella Review.
Balakrishna R, Bjørnerud T, Bemanian M, Aune D, Fadnes LT
Adv Nutr 2022 Dec 22;13(6):2136-2148. doi: 10.1093/advances/nmac077. PMID: 36041171Free PMC Article
Cashew oral immunotherapy for desensitizing cashew-pistachio allergy (NUT CRACKER study).
Elizur A, Appel MY, Nachshon L, Levy MB, Epstein-Rigbi N, Koren Y, Holmqvist M, Porsch H, Lidholm J, Goldberg MR
Allergy 2022 Jun;77(6):1863-1872. Epub 2022 Jan 15 doi: 10.1111/all.15212. PMID: 35000223
Hazelnut Allergy.
Calamelli E, Trozzo A, Di Blasi E, Serra L, Bottau P
Medicina (Kaunas) 2021 Jan 14;57(1) doi: 10.3390/medicina57010067. PMID: 33466577Free PMC Article
Conducting an Oral Food Challenge: An Update to the 2009 Adverse Reactions to Foods Committee Work Group Report.
Bird JA, Leonard S, Groetch M, Assa'ad A, Cianferoni A, Clark A, Crain M, Fausnight T, Fleischer D, Green T, Greenhawt M, Herbert L, Lanser BJ, Mikhail I, Mustafa S, Noone S, Parrish C, Varshney P, Vlieg-Boerstra B, Young MC, Sicherer S, Nowak-Wegrzyn A
J Allergy Clin Immunol Pract 2020 Jan;8(1):75-90.e17. doi: 10.1016/j.jaip.2019.09.029. PMID: 31950914
Food allergy: epidemiology and natural history.
Savage J, Johns CB
Immunol Allergy Clin North Am 2015 Feb;35(1):45-59. Epub 2014 Nov 21 doi: 10.1016/j.iac.2014.09.004. PMID: 25459576Free PMC Article

Diagnosis

EAACI guidelines on the diagnosis of IgE-mediated food allergy.
Santos AF, Riggioni C, Agache I, Akdis CA, Akdis M, Alvarez-Perea A, Alvaro-Lozano M, Ballmer-Weber B, Barni S, Beyer K, Bindslev-Jensen C, Brough HA, Buyuktiryaki B, Chu D, Del Giacco S, Dunn-Galvin A, Eberlein B, Ebisawa M, Eigenmann P, Eiwegger T, Feeney M, Fernandez-Rivas M, Fisher HR, Fleischer DM, Giovannini M, Gray C, Hoffmann-Sommergruber K, Halken S, Hourihane JO, Jones CJ, Jutel M, Knol E, Konstantinou GN, Lack G, Lau S, Marques Mejias A, Marchisotto MJ, Meyer R, Mortz CG, Moya B, Muraro A, Nilsson C, Lopes de Oliveira LC, O'Mahony L, Papadopoulos NG, Perrett K, Peters RL, Podesta M, Poulsen LK, Roberts G, Sampson HA, Schwarze J, Smith P, Tham EH, Untersmayr E, Van Ree R, Venter C, Vickery BP, Vlieg-Boerstra B, Werfel T, Worm M, Du Toit G, Skypala I
Allergy 2023 Dec;78(12):3057-3076. Epub 2023 Oct 10 doi: 10.1111/all.15902. PMID: 37815205
Conducting an Oral Food Challenge: An Update to the 2009 Adverse Reactions to Foods Committee Work Group Report.
Bird JA, Leonard S, Groetch M, Assa'ad A, Cianferoni A, Clark A, Crain M, Fausnight T, Fleischer D, Green T, Greenhawt M, Herbert L, Lanser BJ, Mikhail I, Mustafa S, Noone S, Parrish C, Varshney P, Vlieg-Boerstra B, Young MC, Sicherer S, Nowak-Wegrzyn A
J Allergy Clin Immunol Pract 2020 Jan;8(1):75-90.e17. doi: 10.1016/j.jaip.2019.09.029. PMID: 31950914
Prevalence and Severity of Food Allergies Among US Adults.
Gupta RS, Warren CM, Smith BM, Jiang J, Blumenstock JA, Davis MM, Schleimer RP, Nadeau KC
JAMA Netw Open 2019 Jan 4;2(1):e185630. doi: 10.1001/jamanetworkopen.2018.5630. PMID: 30646188Free PMC Article
Food Allergy.
Iweala OI, Choudhary SK, Commins SP
Curr Gastroenterol Rep 2018 Apr 5;20(5):17. doi: 10.1007/s11894-018-0624-y. PMID: 29623490Free PMC Article
Food allergy: epidemiology and natural history.
Savage J, Johns CB
Immunol Allergy Clin North Am 2015 Feb;35(1):45-59. Epub 2014 Nov 21 doi: 10.1016/j.iac.2014.09.004. PMID: 25459576Free PMC Article

Therapy

Cashew oral immunotherapy for desensitizing cashew-pistachio allergy (NUT CRACKER study).
Elizur A, Appel MY, Nachshon L, Levy MB, Epstein-Rigbi N, Koren Y, Holmqvist M, Porsch H, Lidholm J, Goldberg MR
Allergy 2022 Jun;77(6):1863-1872. Epub 2022 Jan 15 doi: 10.1111/all.15212. PMID: 35000223
Mechanisms of oral immunotherapy.
Barshow SM, Kulis MD, Burks AW, Kim EH
Clin Exp Allergy 2021 Apr;51(4):527-535. Epub 2021 Jan 20 doi: 10.1111/cea.13824. PMID: 33417257Free PMC Article
Cashew Nut Allergy: Clinical Relevance and Allergen Characterisation.
Mendes C, Costa J, Vicente AA, Oliveira MBPP, Mafra I
Clin Rev Allergy Immunol 2019 Aug;57(1):1-22. doi: 10.1007/s12016-016-8580-5. PMID: 27585580
How to diagnose food allergy.
Sato S, Yanagida N, Ebisawa M
Curr Opin Allergy Clin Immunol 2018 Jun;18(3):214-221. doi: 10.1097/ACI.0000000000000441. PMID: 29601353
Tree nut allergy.
Teuber SS, Comstock SS, Sathe SK, Roux KH
Curr Allergy Asthma Rep 2003 Jan;3(1):54-61. doi: 10.1007/s11882-003-0013-x. PMID: 12542995

Prognosis

Mechanisms of oral immunotherapy.
Barshow SM, Kulis MD, Burks AW, Kim EH
Clin Exp Allergy 2021 Apr;51(4):527-535. Epub 2021 Jan 20 doi: 10.1111/cea.13824. PMID: 33417257Free PMC Article
Biomarkers of diagnosis and resolution of food allergy.
Foong RX, Santos AF
Pediatr Allergy Immunol 2021 Feb;32(2):223-233. Epub 2020 Oct 31 doi: 10.1111/pai.13389. PMID: 33020989
The Public Health Impact of Parent-Reported Childhood Food Allergies in the United States.
Gupta RS, Warren CM, Smith BM, Blumenstock JA, Jiang J, Davis MM, Nadeau KC
Pediatrics 2018 Dec;142(6) Epub 2018 Nov 19 doi: 10.1542/peds.2018-1235. PMID: 30455345Free PMC Article
How to diagnose food allergy.
Sato S, Yanagida N, Ebisawa M
Curr Opin Allergy Clin Immunol 2018 Jun;18(3):214-221. doi: 10.1097/ACI.0000000000000441. PMID: 29601353
Food allergy: epidemiology and natural history.
Savage J, Johns CB
Immunol Allergy Clin North Am 2015 Feb;35(1):45-59. Epub 2014 Nov 21 doi: 10.1016/j.iac.2014.09.004. PMID: 25459576Free PMC Article

Clinical prediction guides

Consumption of Nuts and Seeds and Health Outcomes Including Cardiovascular Disease, Diabetes and Metabolic Disease, Cancer, and Mortality: An Umbrella Review.
Balakrishna R, Bjørnerud T, Bemanian M, Aune D, Fadnes LT
Adv Nutr 2022 Dec 22;13(6):2136-2148. doi: 10.1093/advances/nmac077. PMID: 36041171Free PMC Article
Cashew oral immunotherapy for desensitizing cashew-pistachio allergy (NUT CRACKER study).
Elizur A, Appel MY, Nachshon L, Levy MB, Epstein-Rigbi N, Koren Y, Holmqvist M, Porsch H, Lidholm J, Goldberg MR
Allergy 2022 Jun;77(6):1863-1872. Epub 2022 Jan 15 doi: 10.1111/all.15212. PMID: 35000223
Mechanisms of oral immunotherapy.
Barshow SM, Kulis MD, Burks AW, Kim EH
Clin Exp Allergy 2021 Apr;51(4):527-535. Epub 2021 Jan 20 doi: 10.1111/cea.13824. PMID: 33417257Free PMC Article
Prevalence and Severity of Food Allergies Among US Adults.
Gupta RS, Warren CM, Smith BM, Jiang J, Blumenstock JA, Davis MM, Schleimer RP, Nadeau KC
JAMA Netw Open 2019 Jan 4;2(1):e185630. doi: 10.1001/jamanetworkopen.2018.5630. PMID: 30646188Free PMC Article
The Public Health Impact of Parent-Reported Childhood Food Allergies in the United States.
Gupta RS, Warren CM, Smith BM, Blumenstock JA, Jiang J, Davis MM, Nadeau KC
Pediatrics 2018 Dec;142(6) Epub 2018 Nov 19 doi: 10.1542/peds.2018-1235. PMID: 30455345Free PMC Article

Recent systematic reviews

Current options in the management of tree nut allergy: A systematic review and narrative synthesis.
Pasioti M, Xepapadaki P, Mathioudakis AG, Lakoumentas J, Efstathiou E, Papadopoulos NG
Pediatr Allergy Immunol 2024 May;35(5):e14132. doi: 10.1111/pai.14132. PMID: 38727626
Prevalence of tree nut allergy in Europe: A systematic review and meta-analysis.
Spolidoro GCI, Lisik D, Nyassi S, Ioannidou A, Ali MM, Amera YT, Rovner G, Khaleva E, Venter C, van Ree R, Worm M, Vlieg-Boerstra B, Sheikh A, Muraro A, Roberts G, Nwaru BI
Allergy 2024 Feb;79(2):302-323. Epub 2023 Oct 4 doi: 10.1111/all.15905. PMID: 37792850
Tree nut allergy: a systematic review.
Chu DK
Curr Opin Pediatr 2022 Dec 1;34(6):600-608. Epub 2022 Sep 21 doi: 10.1097/MOP.0000000000001180. PMID: 36125008
The Prevalence of Tree Nut Allergy: A Systematic Review.
McWilliam V, Koplin J, Lodge C, Tang M, Dharmage S, Allen K
Curr Allergy Asthma Rep 2015 Sep;15(9):54. doi: 10.1007/s11882-015-0555-8. PMID: 26233427
Systematic review on cashew nut allergy.
van der Valk JP, Dubois AE, Gerth van Wijk R, Wichers HJ, de Jong NW
Allergy 2014 Jun;69(6):692-8. Epub 2014 Apr 15 doi: 10.1111/all.12401. PMID: 24734868

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