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Diffuse large B-cell lymphoma with chronic inflammation

MedGen UID:
1374328
Concept ID:
C4511460
Neoplastic Process
Synonyms: Diffuse large B-cell lymphoma co-occurrent with chronic inflammation caused by Epstein-Barr virus; diffuse large B-cell lymphoma with chronic inflammation; Diffuse large B-cell lymphoma with chronic inflammation caused by Human herpesvirus 4; DLBCL with chronic inflammation
SNOMED CT: Diffuse large B-cell lymphoma co-occurrent with chronic inflammation caused by Epstein-Barr virus (724647003); Diffuse large B-cell lymphoma with chronic inflammation caused by Human herpesvirus 4 (724647003)
 
Monarch Initiative: MONDO:0017601
Orphanet: ORPHA300888

Definition

Diffuse large B-cell lymphoma with chronic inflammation is an Epstein-Barr virus-associated malignant lymphoproliferative disorder, developing in a context of long-standing or slow-growing, chronically inflamed lesions, such as chronic pyothorax, metallic implants in bones and joints, chronic osteomyelitis, chronic venous ulcer, or, rarely granulomatous inflammation. The tumor is usually primarily localized, with no involvement of other organs. [from ORDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDiffuse large B-cell lymphoma with chronic inflammation

Professional guidelines

PubMed

Malpica L, Marques-Piubelli ML, Beltran BE, Chavez JC, Miranda RN, Castillo JJ
Am J Hematol 2022 Jul;97(7):951-965. Epub 2022 May 3 doi: 10.1002/ajh.26579. PMID: 35472248
Beltran BE, Castro D, Paredes S, Miranda RN, Castillo JJ
Am J Hematol 2020 Apr;95(4):435-445. Epub 2020 Feb 29 doi: 10.1002/ajh.25760. PMID: 32072672
Castillo JJ, Beltran BE, Miranda RN, Young KH, Chavez JC, Sotomayor EM
Am J Hematol 2018 Jul;93(7):953-962. doi: 10.1002/ajh.25112. PMID: 29984868

Recent clinical studies

Etiology

Malpica L, Marques-Piubelli ML, Beltran BE, Chavez JC, Miranda RN, Castillo JJ
Am J Hematol 2022 Jul;97(7):951-965. Epub 2022 May 3 doi: 10.1002/ajh.26579. PMID: 35472248
Biernat MM, Wróbel T
Int J Mol Sci 2021 Jul 9;22(14) doi: 10.3390/ijms22147372. PMID: 34298992Free PMC Article
Castillo JJ, Beltran BE, Miranda RN, Young KH, Chavez JC, Sotomayor EM
Am J Hematol 2018 Jul;93(7):953-962. doi: 10.1002/ajh.25112. PMID: 29984868
Smedby KE, Ponzoni M
J Intern Med 2017 Nov;282(5):360-370. Epub 2017 Sep 27 doi: 10.1111/joim.12684. PMID: 28875507
Aozasa K
Int J Hematol 1996 Dec;65(1):9-16. doi: 10.1016/s0925-5710(96)00532-4. PMID: 8990621

Diagnosis

Vets J, Marcelis L, Schepers C, Dorreman Y, Verbeek S, Vanwalleghem L, Gieraerts K, Meylaerts L, Lesaffer J, Devos H, Put N, Snauwaert S, De Paepe P, Tousseyn T
Diagn Pathol 2023 Apr 25;18(1):52. doi: 10.1186/s13000-023-01337-5. PMID: 37098615Free PMC Article
Malpica L, Marques-Piubelli ML, Beltran BE, Chavez JC, Miranda RN, Castillo JJ
Am J Hematol 2022 Jul;97(7):951-965. Epub 2022 May 3 doi: 10.1002/ajh.26579. PMID: 35472248
Sukswai N, Lyapichev K, Khoury JD, Medeiros LJ
Pathology 2020 Jan;52(1):53-67. Epub 2019 Nov 15 doi: 10.1016/j.pathol.2019.08.013. PMID: 31735345
Castillo JJ, Beltran BE, Miranda RN, Young KH, Chavez JC, Sotomayor EM
Am J Hematol 2018 Jul;93(7):953-962. doi: 10.1002/ajh.25112. PMID: 29984868
Elton TS, Selemon H, Elton SM, Parinandi NL
Gene 2013 Dec 10;532(1):1-12. Epub 2012 Dec 14 doi: 10.1016/j.gene.2012.12.009. PMID: 23246696

Therapy

Vets J, Marcelis L, Schepers C, Dorreman Y, Verbeek S, Vanwalleghem L, Gieraerts K, Meylaerts L, Lesaffer J, Devos H, Put N, Snauwaert S, De Paepe P, Tousseyn T
Diagn Pathol 2023 Apr 25;18(1):52. doi: 10.1186/s13000-023-01337-5. PMID: 37098615Free PMC Article
Chiu CY, Zhang HC, Westin J, Hosing C, Torres HA
Transplant Cell Ther 2022 Nov;28(11):788.e1-788.e5. Epub 2022 Aug 27 doi: 10.1016/j.jtct.2022.08.020. PMID: 36031077
Beltran BE, Castro D, Paredes S, Miranda RN, Castillo JJ
Am J Hematol 2020 Apr;95(4):435-445. Epub 2020 Feb 29 doi: 10.1002/ajh.25760. PMID: 32072672
Kellogg BC, Hiro ME, Payne WG
Ann Plast Surg 2014 Oct;73(4):461-4. doi: 10.1097/SAP.0b013e31827faff2. PMID: 23722577
Aozasa K
Int J Hematol 1996 Dec;65(1):9-16. doi: 10.1016/s0925-5710(96)00532-4. PMID: 8990621

Prognosis

Vets J, Marcelis L, Schepers C, Dorreman Y, Verbeek S, Vanwalleghem L, Gieraerts K, Meylaerts L, Lesaffer J, Devos H, Put N, Snauwaert S, De Paepe P, Tousseyn T
Diagn Pathol 2023 Apr 25;18(1):52. doi: 10.1186/s13000-023-01337-5. PMID: 37098615Free PMC Article
Malpica L, Marques-Piubelli ML, Beltran BE, Chavez JC, Miranda RN, Castillo JJ
Am J Hematol 2022 Jul;97(7):951-965. Epub 2022 May 3 doi: 10.1002/ajh.26579. PMID: 35472248
Biernat MM, Wróbel T
Int J Mol Sci 2021 Jul 9;22(14) doi: 10.3390/ijms22147372. PMID: 34298992Free PMC Article
Castillo JJ, Beltran BE, Miranda RN, Young KH, Chavez JC, Sotomayor EM
Am J Hematol 2018 Jul;93(7):953-962. doi: 10.1002/ajh.25112. PMID: 29984868
Smedby KE, Ponzoni M
J Intern Med 2017 Nov;282(5):360-370. Epub 2017 Sep 27 doi: 10.1111/joim.12684. PMID: 28875507

Clinical prediction guides

Vets J, Marcelis L, Schepers C, Dorreman Y, Verbeek S, Vanwalleghem L, Gieraerts K, Meylaerts L, Lesaffer J, Devos H, Put N, Snauwaert S, De Paepe P, Tousseyn T
Diagn Pathol 2023 Apr 25;18(1):52. doi: 10.1186/s13000-023-01337-5. PMID: 37098615Free PMC Article
Malpica L, Marques-Piubelli ML, Beltran BE, Chavez JC, Miranda RN, Castillo JJ
Am J Hematol 2022 Jul;97(7):951-965. Epub 2022 May 3 doi: 10.1002/ajh.26579. PMID: 35472248
Beltran BE, Castro D, Paredes S, Miranda RN, Castillo JJ
Am J Hematol 2020 Apr;95(4):435-445. Epub 2020 Feb 29 doi: 10.1002/ajh.25760. PMID: 32072672
Castillo JJ, Beltran BE, Miranda RN, Young KH, Chavez JC, Sotomayor EM
Am J Hematol 2018 Jul;93(7):953-962. doi: 10.1002/ajh.25112. PMID: 29984868
McAulay KA, Jarrett RF
Tissue Antigens 2015 Aug;86(2):98-113. doi: 10.1111/tan.12604. PMID: 26189878

Recent systematic reviews

Parra-Medina R, Rocha F, Castañeda-González JP, Moreno-Lucero P, Veloza L, Romero-Rojas AE
Medicine (Baltimore) 2022 Jul 15;101(28):e28988. doi: 10.1097/MD.0000000000028988. PMID: 35838994

Supplemental Content

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