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Mild glandular cell atypia

MedGen UID:
137705
•Concept ID:
C0333881
•
Cell or Molecular Dysfunction
Synonym: Mild Glandular Cell Atypia
SNOMED CT: Mild glandular cell atypia (88948004)

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMild glandular cell atypia

Professional guidelines

PubMed

Very well-differentiated gastric carcinoma of intestinal type: analysis of diagnostic criteria.
Ushiku T, Arnason T, Ban S, Hishima T, Shimizu M, Fukayama M, Lauwers GY
Mod Pathol 2013 Dec;26(12):1620-31. Epub 2013 May 31 doi: 10.1038/modpathol.2013.98. PMID: 23723017
Preoperative differential diagnosis of minimal deviation adenocarcinoma and lobular endocervical glandular hyperplasia of the uterine cervix: a multicenter study of clinicopathology and magnetic resonance imaging findings.
Takatsu A, Shiozawa T, Miyamoto T, Kurosawa K, Kashima H, Yamada T, Kaku T, Mikami Y, Kiyokawa T, Tsuda H, Ishii K, Togashi K, Koyama T, Fujinaga Y, Kadoya M, Hashi A, Susumu N, Konishi I
Int J Gynecol Cancer 2011 Oct;21(7):1287-96. doi: 10.1097/IGC.0b013e31821f746c. PMID: 21685796

Recent clinical studies

Etiology

Very well-differentiated gastric carcinoma of intestinal type: analysis of diagnostic criteria.
Ushiku T, Arnason T, Ban S, Hishima T, Shimizu M, Fukayama M, Lauwers GY
Mod Pathol 2013 Dec;26(12):1620-31. Epub 2013 May 31 doi: 10.1038/modpathol.2013.98. PMID: 23723017
Papillary tissue fragments in cervicovaginal (Pap) smears: cytomorphologic characteristics and clinicopathologic significance.
Stoll LM, Johnson MW, Ali SZ
Diagn Cytopathol 2011 Sep;39(9):657-62. Epub 2010 Oct 14 doi: 10.1002/dc.21443. PMID: 20949454
Endometrial hyperplasia.
Mills AM, Longacre TA
Semin Diagn Pathol 2010 Nov;27(4):199-214. doi: 10.1053/j.semdp.2010.09.002. PMID: 21309256
Endocervical glandular atypia: does a preneoplastic lesion of adenocarcinoma in situ exist?
Goldstein NS, Ahmad E, Hussain M, Hankin RC, Perez-Reyes N
Am J Clin Pathol 1998 Aug;110(2):200-9. doi: 10.1093/ajcp/110.2.200. PMID: 9704619
Nephrogenic adenoma of the urinary bladder: a comparison of its cytologic and histopathologic features in ten cases.
Rutgers JL, Young RH
Diagn Cytopathol 1988;4(3):210-6. doi: 10.1002/dc.2840040307. PMID: 2474416

Diagnosis

Cytological features of atypical polypoid adenomyoma of the endometrium: A case report with literature review.
Ebisu Y, Arimoto T, Ishida M, Miyasaka C, Uemura Y, Okada H, Tsuta K
Diagn Cytopathol 2017 Apr;45(4):345-349. Epub 2017 Feb 4 doi: 10.1002/dc.23665. PMID: 28160434
Papillary tissue fragments in cervicovaginal (Pap) smears: cytomorphologic characteristics and clinicopathologic significance.
Stoll LM, Johnson MW, Ali SZ
Diagn Cytopathol 2011 Sep;39(9):657-62. Epub 2010 Oct 14 doi: 10.1002/dc.21443. PMID: 20949454
Endometrial hyperplasia.
Mills AM, Longacre TA
Semin Diagn Pathol 2010 Nov;27(4):199-214. doi: 10.1053/j.semdp.2010.09.002. PMID: 21309256
Nephrogenic adenoma of the urinary bladder: a comparison of its cytologic and histopathologic features in ten cases.
Rutgers JL, Young RH
Diagn Cytopathol 1988;4(3):210-6. doi: 10.1002/dc.2840040307. PMID: 2474416
The cytodynamics of endometrial hyperplasia and carcinoma. A review.
Ferenczy A, Gelfand MM, Tzipris F
Ann Pathol 1983 Sep;3(3):189-201. PMID: 6354201

Therapy

Diffuse malignant biphasic peritoneal mesothelioma with cystic areas.
Cabibi D, Tutino R, Salamone G, Cocorullo G, Agrusa A, Gulotta G
Ann Ital Chir 2016 Jun 20;87 PMID: 27320084
Pseudoinfiltrative tubal metaplasia of the endocervix: a potential form of in utero diethylstilbestrol exposure-related adenosis simulating minimal deviation adenocarcinoma.
Vang R, Vinh TN, Burks RT, Barner R, Kurman RJ, Ronnett BM
Int J Gynecol Pathol 2005 Oct;24(4):391-8. doi: 10.1097/01.pgp.0000170064.95465.5c. PMID: 16175088
Dysplastic changes in gastric fundic gland polyps of patients with familial adenomatous polyposis.
Bertoni G, Sassatelli R, Nigrisoli E, Pennazio M, Tansini P, Arrigoni A, Rossini FP, Ponz de Leon M, Bedogni G
Ital J Gastroenterol Hepatol 1999 Apr;31(3):192-7. PMID: 10379478
Comparative pathology of dome and trigone of urinary bladder mucosa in paraplegics and tetraplegics.
van Velzen D, Krishnan KR, Parsons KF, Soni BM, Fraser MH, Howard CV, Vaidyanathan S
Paraplegia 1995 Oct;33(10):565-72. doi: 10.1038/sc.1995.122. PMID: 8848310
Cytopathologic changes associated with intrauterine contraceptive devices. A review of cervico-vaginal smears in 350 women.
Pillay B, Gregory AR, Subbiah M
Med J Malaysia 1994 Mar;49(1):74-7. PMID: 8057995

Prognosis

Cutaneous digital papillary adenocarcinoma: a clinicopathologic study of 31 cases of a rare neoplasm with new observations.
Suchak R, Wang WL, Prieto VG, Ivan D, Lazar AJ, Brenn T, Calonje E
Am J Surg Pathol 2012 Dec;36(12):1883-91. doi: 10.1097/PAS.0b013e31826320ec. PMID: 23026931
Papillary tissue fragments in cervicovaginal (Pap) smears: cytomorphologic characteristics and clinicopathologic significance.
Stoll LM, Johnson MW, Ali SZ
Diagn Cytopathol 2011 Sep;39(9):657-62. Epub 2010 Oct 14 doi: 10.1002/dc.21443. PMID: 20949454
Cytological findings of mixed squamous cell and glandular papilloma in the lung.
Kadota K, Haba R, Katsuki N, Hayashi T, Miyai Y, Bando K, Shibuya S, Kushida Y
Diagn Cytopathol 2010 Dec;38(12):913-7. doi: 10.1002/dc.21334. PMID: 20301213
Prostate carcinoma with squamous differentiation: an analysis of 33 cases.
Parwani AV, Kronz JD, Genega EM, Gaudin P, Chang S, Epstein JI
Am J Surg Pathol 2004 May;28(5):651-7. doi: 10.1097/00000478-200405000-00014. PMID: 15105655
Minimal deviation endocervical adenocarcinoma: clinical and histologic features, immunohistochemical staining for carcinoembryonic antigen, and differentiation from confusing benign lesions.
Michael H, Grawe L, Kraus FT
Int J Gynecol Pathol 1984;3(3):261-76. PMID: 6500801

Clinical prediction guides

Ovarian Mucinous Tumor Presenting Atypical Lobular Endocervical Glandular Hyperplasia-Like Appearance in a Patient With Germline STK11 p.F354L Variant: A Case Report.
Yoshida H, Hiranuma K, Nakahara M, Kobayashi-Kato M, Tanase Y, Uno M, Shiraishi K, Ishikawa M, Kato T
Int J Surg Pathol 2024 Apr;32(2):394-400. Epub 2023 May 24 doi: 10.1177/10668969231177256. PMID: 37226494
Cytological features of atypical polypoid adenomyoma of the endometrium: A case report with literature review.
Ebisu Y, Arimoto T, Ishida M, Miyasaka C, Uemura Y, Okada H, Tsuta K
Diagn Cytopathol 2017 Apr;45(4):345-349. Epub 2017 Feb 4 doi: 10.1002/dc.23665. PMID: 28160434
Very well-differentiated gastric carcinoma of intestinal type: analysis of diagnostic criteria.
Ushiku T, Arnason T, Ban S, Hishima T, Shimizu M, Fukayama M, Lauwers GY
Mod Pathol 2013 Dec;26(12):1620-31. Epub 2013 May 31 doi: 10.1038/modpathol.2013.98. PMID: 23723017
Cutaneous digital papillary adenocarcinoma: a clinicopathologic study of 31 cases of a rare neoplasm with new observations.
Suchak R, Wang WL, Prieto VG, Ivan D, Lazar AJ, Brenn T, Calonje E
Am J Surg Pathol 2012 Dec;36(12):1883-91. doi: 10.1097/PAS.0b013e31826320ec. PMID: 23026931
Adenomyofibroma of the endometrium with skeletal muscle differentiation.
Sinkre P, Miller DS, Milchgrub S, Hameed A
Int J Gynecol Pathol 2000 Jul;19(3):280-3. doi: 10.1097/00004347-200007000-00014. PMID: 10907179

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