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Central Nervous System Undifferentiated Pleomorphic Sarcoma

MedGen UID:
1380462
Concept ID:
C4329641
Neoplastic Process

Definition

A rare undifferentiated pleomorphic sarcoma (formerly known as malignant fibrous histiocytoma) involving the central nervous system. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCentral Nervous System Undifferentiated Pleomorphic Sarcoma

Recent clinical studies

Etiology

Mezzacappa FM, Smith FK, Zhang W, Gard A, Cabuk FK, Gonzalez-Gomez I, Monforte HL, Liang J, Singh O, Quezado MM, Aldape KD, Gokden M, Bridge JA, Chen J
Acta Neuropathol Commun 2024 Jan 30;12(1):17. doi: 10.1186/s40478-024-01721-2. PMID: 38291529Free PMC Article
Tauziède-Espariat A, Sievers P, Larousserie F, Benzakoun J, Guillemot D, Pierron G, Duchesne M, Uro-Coste E, Roux A, Vasiljevic A, Fenouil T, Meyronet D, Mokhtari K, Polivka M, Rousseau A, Bost-Bezeaud F, Akoury S, Pallud J, Benevello C, Hasty L, Gareton A, Lechapt E, Chrétien F, Blauwblomme T, Beccaria K, Puget S, Sahm F, Varlet P; RENOCLIP-LOC
Brain Pathol 2022 Jan;32(1):e13010. Epub 2021 Jul 27 doi: 10.1111/bpa.13010. PMID: 34314078Free PMC Article
Spaulding R 4th, Koumoundouros T, Parker JC Jr
Ann Clin Lab Sci 2013 Spring;43(2):172-5. PMID: 23694792
Broniscer A, Ke W, Fuller CE, Wu J, Gajjar A, Kun LE
Cancer 2004 May 15;100(10):2246-52. doi: 10.1002/cncr.20253. PMID: 15139071
Oliveira AM, Scheithauer BW, Salomao DR, Parisi JE, Burger PC, Nascimento AG
Am J Surg Pathol 2002 Aug;26(8):1056-63. doi: 10.1097/00000478-200208000-00011. PMID: 12170093

Diagnosis

Bailo M, Gagliardi F, Boari N, Spina A, Piloni M, Castellano A, Mortini P
Adv Exp Med Biol 2023;1405:73-97. doi: 10.1007/978-3-031-23705-8_3. PMID: 37452935
Tauziède-Espariat A, Pierron G, Guillemot D, Benevello C, Pallud J, Benzakoun J, Hasty L, Métais A, Chrétien F, Varlet P
Brain Tumor Pathol 2023 Jan;40(1):35-39. Epub 2022 Sep 15 doi: 10.1007/s10014-022-00443-4. PMID: 36107277
Spaulding R 4th, Koumoundouros T, Parker JC Jr
Ann Clin Lab Sci 2013 Spring;43(2):172-5. PMID: 23694792
Gelincik I
Indian J Pathol Microbiol 2012 Jul-Sep;55(3):402-5. doi: 10.4103/0377-4929.101759. PMID: 23032846
Jellinger K, Paulus W
Brain Pathol 1991 Jan;1(2):79-87. doi: 10.1111/j.1750-3639.1991.tb00643.x. PMID: 1669699

Therapy

Inaba H, Khan RB, Laningham FH, Crews KR, Pui CH, Daw NC
Ann Oncol 2008 Jan;19(1):178-84. Epub 2007 Oct 17 doi: 10.1093/annonc/mdm466. PMID: 17947226
Broniscer A, Ke W, Fuller CE, Wu J, Gajjar A, Kun LE
Cancer 2004 May 15;100(10):2246-52. doi: 10.1002/cncr.20253. PMID: 15139071
Biegel JA, Perilongo G, Rorke LB, Parmiter AH, Emanuel BS
Genes Chromosomes Cancer 1992 Jun;4(4):309-13. doi: 10.1002/gcc.2870040406. PMID: 1377937
Raney RB Jr, Allen A, O'Neill J, Handler SD, Uri A, Littman P
Cancer 1986 Jun 1;57(11):2198-201. doi: 10.1002/1097-0142(19860601)57:11<2198::aid-cncr2820571120>3.0.co;2-x. PMID: 3008978
Holtzman E, Schiby G, Segal P, Priel I
J Am Coll Cardiol 1986 Apr;7(4):956-60. doi: 10.1016/s0735-1097(86)80365-5. PMID: 3007598

Prognosis

Gupta P, Siraj F, Shankar KB, Rawat M, Mankotia DS, Yadav V, Dagar A
J Cancer Res Ther 2024 Jan 1;20(1):238-242. Epub 2023 Apr 7 doi: 10.4103/jcrt.jcrt_383_22. PMID: 38554327
Mezzacappa FM, Smith FK, Zhang W, Gard A, Cabuk FK, Gonzalez-Gomez I, Monforte HL, Liang J, Singh O, Quezado MM, Aldape KD, Gokden M, Bridge JA, Chen J
Acta Neuropathol Commun 2024 Jan 30;12(1):17. doi: 10.1186/s40478-024-01721-2. PMID: 38291529Free PMC Article
Bailo M, Gagliardi F, Boari N, Spina A, Piloni M, Castellano A, Mortini P
Adv Exp Med Biol 2023;1405:73-97. doi: 10.1007/978-3-031-23705-8_3. PMID: 37452935
Spaulding R 4th, Koumoundouros T, Parker JC Jr
Ann Clin Lab Sci 2013 Spring;43(2):172-5. PMID: 23694792
Oliveira AM, Scheithauer BW, Salomao DR, Parisi JE, Burger PC, Nascimento AG
Am J Surg Pathol 2002 Aug;26(8):1056-63. doi: 10.1097/00000478-200208000-00011. PMID: 12170093

Clinical prediction guides

Tauziède-Espariat A, Pierron G, Guillemot D, Benevello C, Pallud J, Benzakoun J, Hasty L, Métais A, Chrétien F, Varlet P
Brain Tumor Pathol 2023 Jan;40(1):35-39. Epub 2022 Sep 15 doi: 10.1007/s10014-022-00443-4. PMID: 36107277
Kim NR, Kim SI, Park JW, Park CK, Chung CK, Choi SH, Yun H, Park SH
Neuropathology 2022 Aug;42(4):257-268. Epub 2022 Jun 22 doi: 10.1111/neup.12814. PMID: 35730186
Zámecník J, Cerný R, Bartos A, Jerábek J, Bojar M
Cesk Patol 2004 Apr;40(2):63-7. PMID: 15233019
Bodey B, Bodey B Jr, Siegel SE, Kaiser HE
In Vivo 1999 Jul-Aug;13(4):357-73. PMID: 10586378
Kalyanaraman UP, Taraska JJ, Fierer JA, Elwood PW
J Neurosurg 1981 Dec;55(6):957-62. doi: 10.3171/jns.1981.55.6.0957. PMID: 6271934

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