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Suppurative lymphadenitis

MedGen UID:
140258
•Concept ID:
C0392051
•
Disease or Syndrome
Synonyms: Suppurative Lymphadenitis; suppurative lymphadenitis; Suppurative lymphadenopathy; suppurative lymphadenopathy
SNOMED CT: Suppurative lymphadenopathy (48573006); Suppurative lymphadenitis (48573006)
 
Monarch Initiative: MONDO:0003069

Definition

A form of lymphadenitis that is characterized by formation of pus; it is most often caused by staphylococcal or streptococcal bacteria. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSuppurative lymphadenitis

Professional guidelines

PubMed

Pediatric deep neck infections: Clinical description and analysis of therapeutic management.
Demongeot N, Akkari M, Blanchet C, Godreuil S, Prodhomme O, Leboucq N, Mondain M, Jeziorski E
Arch Pediatr 2022 Feb;29(2):128-132. Epub 2021 Dec 23 doi: 10.1016/j.arcped.2021.11.011. PMID: 34955300
Management of Bacille Calmette-Guérin Lymphadenitis and Abscess in Immunocompetent Children: A Systematic Review.
Villanueva P, Pittet LF, Curtis N
Pediatr Infect Dis J 2021 Nov 1;40(11):1037-1045. doi: 10.1097/INF.0000000000003237. PMID: 34636800
Clinical presentation and treatment of melioidosis in the head and neck region.
Mahawerawat K, Kasemsiri P
J Laryngol Otol 2018 Sep;132(9):827-831. Epub 2018 Sep 5 doi: 10.1017/S0022215118001391. PMID: 30180912

Recent clinical studies

Etiology

Observer- and radiomics model-based computed tomography classification of suppurative versus tuberculous lymphadenitis complicated with nodal necrosis of the neck in children.
Zhang R, Xu Y, Gao S, Jing Y, Li W
Pediatr Radiol 2023 Dec;53(13):2586-2596. Epub 2023 Oct 9 doi: 10.1007/s00247-023-05761-z. PMID: 37806973
Cervical suppurative lymphadenitis in children: microbiology, primary sites of infection, and evaluation of antibiotic treatment.
Nielsen NØ, Nørlinger C, Greve T, Klug TE
Eur Arch Otorhinolaryngol 2022 Jun;279(6):3053-3062. Epub 2021 Oct 8 doi: 10.1007/s00405-021-07115-7. PMID: 34623496
Surgical treatment of non-tuberculous mycobacterial lymphadenitis in children: Our experience and a narrative review.
Torretta S, Gaffuri M, Ibba T, Capaccio P, Marchisio P, Maruca A, Bosis S, Pignataro L
Int J Immunopathol Pharmacol 2018 Jan-Dec;32:2058738418806413. doi: 10.1177/2058738418806413. PMID: 30354841Free PMC Article
Chronic Granulomatous Disease.
Rawat A, Bhattad S, Singh S
Indian J Pediatr 2016 Apr;83(4):345-53. Epub 2016 Feb 11 doi: 10.1007/s12098-016-2040-3. PMID: 26865172
Head and neck space infections.
Larawin V, Naipao J, Dubey SP
Otolaryngol Head Neck Surg 2006 Dec;135(6):889-93. doi: 10.1016/j.otohns.2006.07.007. PMID: 17141079

Diagnosis

Kikuchi Cervical Lymphadenitis in Children: Ultrasound Differentiation From Common Infectious Lymphadenitis.
Park S, Kim JY, Ryu YJ, Lee H
J Ultrasound Med 2021 Oct;40(10):2069-2078. Epub 2020 Dec 2 doi: 10.1002/jum.15584. PMID: 33263358
Surgical treatment of non-tuberculous mycobacterial lymphadenitis in children: Our experience and a narrative review.
Torretta S, Gaffuri M, Ibba T, Capaccio P, Marchisio P, Maruca A, Bosis S, Pignataro L
Int J Immunopathol Pharmacol 2018 Jan-Dec;32:2058738418806413. doi: 10.1177/2058738418806413. PMID: 30354841Free PMC Article
Chronic Granulomatous Disease.
Rawat A, Bhattad S, Singh S
Indian J Pediatr 2016 Apr;83(4):345-53. Epub 2016 Feb 11 doi: 10.1007/s12098-016-2040-3. PMID: 26865172
Granulomatous lymphadenitis.
Asano S
J Clin Exp Hematop 2012;52(1):1-16. doi: 10.3960/jslrt.52.1. PMID: 22706525
Bacille Calmette-Guérin lymphadenitis.
Goraya JS, Virdi VS
Postgrad Med J 2002 Jun;78(920):327-9. doi: 10.1136/pmj.78.920.327. PMID: 12151684Free PMC Article

Therapy

Pediatric deep neck infections: Clinical description and analysis of therapeutic management.
Demongeot N, Akkari M, Blanchet C, Godreuil S, Prodhomme O, Leboucq N, Mondain M, Jeziorski E
Arch Pediatr 2022 Feb;29(2):128-132. Epub 2021 Dec 23 doi: 10.1016/j.arcped.2021.11.011. PMID: 34955300
Cervical suppurative lymphadenitis in children: microbiology, primary sites of infection, and evaluation of antibiotic treatment.
Nielsen NØ, Nørlinger C, Greve T, Klug TE
Eur Arch Otorhinolaryngol 2022 Jun;279(6):3053-3062. Epub 2021 Oct 8 doi: 10.1007/s00405-021-07115-7. PMID: 34623496
Management of Bacille Calmette-Guérin Lymphadenitis and Abscess in Immunocompetent Children: A Systematic Review.
Villanueva P, Pittet LF, Curtis N
Pediatr Infect Dis J 2021 Nov 1;40(11):1037-1045. doi: 10.1097/INF.0000000000003237. PMID: 34636800
Management and outcome of Bacille Calmette-Guérin vaccine adverse reactions.
Venkataraman A, Yusuff M, Liebeschuetz S, Riddell A, Prendergast AJ
Vaccine 2015 Oct 5;33(41):5470-5474. Epub 2015 Aug 12 doi: 10.1016/j.vaccine.2015.07.103. PMID: 26275478Free PMC Article
Bacille Calmette-Guérin lymphadenitis.
Goraya JS, Virdi VS
Postgrad Med J 2002 Jun;78(920):327-9. doi: 10.1136/pmj.78.920.327. PMID: 12151684Free PMC Article

Prognosis

Observer- and radiomics model-based computed tomography classification of suppurative versus tuberculous lymphadenitis complicated with nodal necrosis of the neck in children.
Zhang R, Xu Y, Gao S, Jing Y, Li W
Pediatr Radiol 2023 Dec;53(13):2586-2596. Epub 2023 Oct 9 doi: 10.1007/s00247-023-05761-z. PMID: 37806973
Chronic Granulomatous Disease.
Rawat A, Bhattad S, Singh S
Indian J Pediatr 2016 Apr;83(4):345-53. Epub 2016 Feb 11 doi: 10.1007/s12098-016-2040-3. PMID: 26865172
Granulomatous lymphadenitis.
Asano S
J Clin Exp Hematop 2012;52(1):1-16. doi: 10.3960/jslrt.52.1. PMID: 22706525
Head and neck space infections.
Larawin V, Naipao J, Dubey SP
Otolaryngol Head Neck Surg 2006 Dec;135(6):889-93. doi: 10.1016/j.otohns.2006.07.007. PMID: 17141079
Bacille Calmette-Guérin lymphadenitis.
Goraya JS, Virdi VS
Postgrad Med J 2002 Jun;78(920):327-9. doi: 10.1136/pmj.78.920.327. PMID: 12151684Free PMC Article

Clinical prediction guides

Observer- and radiomics model-based computed tomography classification of suppurative versus tuberculous lymphadenitis complicated with nodal necrosis of the neck in children.
Zhang R, Xu Y, Gao S, Jing Y, Li W
Pediatr Radiol 2023 Dec;53(13):2586-2596. Epub 2023 Oct 9 doi: 10.1007/s00247-023-05761-z. PMID: 37806973
Pediatric deep neck infections: Clinical description and analysis of therapeutic management.
Demongeot N, Akkari M, Blanchet C, Godreuil S, Prodhomme O, Leboucq N, Mondain M, Jeziorski E
Arch Pediatr 2022 Feb;29(2):128-132. Epub 2021 Dec 23 doi: 10.1016/j.arcped.2021.11.011. PMID: 34955300
Factors Affecting Cervical Lymph Node Suppuration in Oropharyngeal Tularemia Cases.
Ince N, Gozdas HT
J Coll Physicians Surg Pak 2021 Feb;31(2):193-196. doi: 10.29271/jcpsp.2021.02.193. PMID: 33645188
Clinical presentation and treatment of melioidosis in the head and neck region.
Mahawerawat K, Kasemsiri P
J Laryngol Otol 2018 Sep;132(9):827-831. Epub 2018 Sep 5 doi: 10.1017/S0022215118001391. PMID: 30180912
Granulomatous lymphadenitis.
Asano S
J Clin Exp Hematop 2012;52(1):1-16. doi: 10.3960/jslrt.52.1. PMID: 22706525

Recent systematic reviews

Management of Bacille Calmette-Guérin Lymphadenitis and Abscess in Immunocompetent Children: A Systematic Review.
Villanueva P, Pittet LF, Curtis N
Pediatr Infect Dis J 2021 Nov 1;40(11):1037-1045. doi: 10.1097/INF.0000000000003237. PMID: 34636800

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