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Bladder neck obstruction

MedGen UID:
14151
•Concept ID:
C0005694
•
Disease or Syndrome
Synonyms: Bladder Neck Obstruction; Bladder Outlet Obstruction; Urinary Bladder Neck Obstruction
SNOMED CT: Bladder neck obstruction (399072004); Vesicourethral orifice obstruction (399072004); Obstruction of neck of urinary bladder (399072004); BNO - bladder neck obstruction (399072004)
 
Monarch Initiative: MONDO:0006679

Definition

Blockage of the opening between the bladder and the urethra resulting in the reduction or prevention of the urine flow from the bladder into the urethra. [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBladder neck obstruction

Professional guidelines

PubMed

The Role of Video Urodynamics in the Management of the Valve Bladder.
Concodora CW, Reddy PP, VanderBrink BA
Curr Urol Rep 2017 Mar;18(3):24. doi: 10.1007/s11934-017-0670-2. PMID: 28233231
Pharmacologic management of non-neurogenic functional obstruction in women.
Cohn JA, Brown ET, Reynolds WS, Kaufman MR, Dmochowski RR
Expert Opin Drug Metab Toxicol 2016 Jun;12(6):657-67. Epub 2016 Apr 28 doi: 10.1080/17425255.2016.1178239. PMID: 27095013
Fetal therapy for the treatment of congenital bladder neck obstruction.
Kilby MD, Morris RK
Nat Rev Urol 2014 Jul;11(7):412-9. Epub 2014 Jun 17 doi: 10.1038/nrurol.2014.132. PMID: 24934451

Recent clinical studies

Etiology

Congenital urinary tract obstruction.
Cheung KW, Morris RK, Kilby MD
Best Pract Res Clin Obstet Gynaecol 2019 Jul;58:78-92. Epub 2019 Jan 11 doi: 10.1016/j.bpobgyn.2019.01.003. PMID: 30819578
Urodynamic Outcomes After Aquablation.
Pimentel MA, Yassaie O, Gilling P
Urology 2019 Apr;126:165-170. Epub 2019 Feb 2 doi: 10.1016/j.urology.2019.01.020. PMID: 30721737
The devastated bladder outlet: treatment options.
Riedmiller H, Kocot A
Curr Opin Urol 2015 Jul;25(4):352-6. doi: 10.1097/MOU.0000000000000185. PMID: 26049880
Fetal therapy for the treatment of congenital bladder neck obstruction.
Kilby MD, Morris RK
Nat Rev Urol 2014 Jul;11(7):412-9. Epub 2014 Jun 17 doi: 10.1038/nrurol.2014.132. PMID: 24934451
Bladder neck contractures and the prostate cancer survivor.
Song JS, Eswara JR, Brandes SB
Curr Opin Urol 2014 Jul;24(4):389-94. doi: 10.1097/MOU.0000000000000065. PMID: 24901516

Diagnosis

Bladder outlet obstruction.
Society for Maternal-Fetal Medicine (SMFM), Mardy A
Am J Obstet Gynecol 2021 Nov;225(5):B9-B11. Epub 2021 Sep 8 doi: 10.1016/j.ajog.2021.06.039. PMID: 34507791
Congenital urinary tract obstruction.
Cheung KW, Morris RK, Kilby MD
Best Pract Res Clin Obstet Gynaecol 2019 Jul;58:78-92. Epub 2019 Jan 11 doi: 10.1016/j.bpobgyn.2019.01.003. PMID: 30819578
What is a disease? What is the disease clinical benign prostatic hyperplasia (BPH)?
Foo KT
World J Urol 2019 Jul;37(7):1293-1296. Epub 2019 Feb 25 doi: 10.1007/s00345-019-02691-0. PMID: 30805683Free PMC Article
Female Bladder Outlet Obstruction.
Hoffman DS, Nitti VW
Curr Urol Rep 2016 Apr;17(4):31. doi: 10.1007/s11934-016-0586-2. PMID: 26902625
Diagnosis and Management of Bladder Outlet Obstruction in Women.
Lin CD, Kuo HC, Yang SS
Low Urin Tract Symptoms 2016 Jan;8(1):30-7. Epub 2015 Mar 26 doi: 10.1111/luts.12094. PMID: 26789540

Therapy

Congenital urinary tract obstruction.
Cheung KW, Morris RK, Kilby MD
Best Pract Res Clin Obstet Gynaecol 2019 Jul;58:78-92. Epub 2019 Jan 11 doi: 10.1016/j.bpobgyn.2019.01.003. PMID: 30819578
A Systematic Review and Meta-analysis of Functional Outcomes and Complications Following Transurethral Procedures for Lower Urinary Tract Symptoms Resulting from Benign Prostatic Obstruction: An Update.
Cornu JN, Ahyai S, Bachmann A, de la Rosette J, Gilling P, Gratzke C, McVary K, Novara G, Woo H, Madersbacher S
Eur Urol 2015 Jun;67(6):1066-1096. Epub 2014 Jun 25 doi: 10.1016/j.eururo.2014.06.017. PMID: 24972732
Bladder neck contractures and the prostate cancer survivor.
Song JS, Eswara JR, Brandes SB
Curr Opin Urol 2014 Jul;24(4):389-94. doi: 10.1097/MOU.0000000000000065. PMID: 24901516
Female urethral dilation.
Bazi T, Abou-Ghannam G, Khauli R
Int Urogynecol J 2013 Sep;24(9):1435-44. Epub 2013 Feb 14 doi: 10.1007/s00192-013-2055-5. PMID: 23408001
Anticholinergic, antimuscarinic bronchodilators.
Gross NJ, Skorodin MS
Am Rev Respir Dis 1984 May;129(5):856-70. doi: 10.1164/arrd.1984.129.5.856. PMID: 6372560

Prognosis

Bladder outlet obstruction.
Society for Maternal-Fetal Medicine (SMFM), Mardy A
Am J Obstet Gynecol 2021 Nov;225(5):B9-B11. Epub 2021 Sep 8 doi: 10.1016/j.ajog.2021.06.039. PMID: 34507791
Fetal bladder outflow obstruction: Interventions, outcomes and management uncertainties.
Farrugia MK
Early Hum Dev 2020 Nov;150:105189. Epub 2020 Sep 10 doi: 10.1016/j.earlhumdev.2020.105189. PMID: 32978001
Congenital urinary tract obstruction.
Cheung KW, Morris RK, Kilby MD
Best Pract Res Clin Obstet Gynaecol 2019 Jul;58:78-92. Epub 2019 Jan 11 doi: 10.1016/j.bpobgyn.2019.01.003. PMID: 30819578
Bladder Neck Contracture After Endoscopic Surgery for Benign Prostatic Obstruction: Incidence, Treatment, and Outcomes.
Primiceri G, Castellan P, Marchioni M, Schips L, Cindolo L
Curr Urol Rep 2017 Aug 9;18(10):79. doi: 10.1007/s11934-017-0723-6. PMID: 28795367
MicroRNAs in Bladder Outlet Obstruction: Relationship to Growth and Matrix Remodelling.
Ekman M, Albinsson S, Uvelius B, Swärd K
Basic Clin Pharmacol Toxicol 2016 Oct;119 Suppl 3:5-17. Epub 2016 Jan 14 doi: 10.1111/bcpt.12534. PMID: 26612603

Clinical prediction guides

Bladder Outlet Obstruction Relief and Symptom Improvement Following Medical and Surgical Therapies for Lower Urinary Tract Symptoms Suggestive of Benign Prostatic Hyperplasia: A Systematic Review.
Creta M, Russo GI, Bhojani N, Drake MJ, Gratzke C, Peyronnet B, Roehrborn C, Tikkinen KAO, Cornu JN, Fusco F
Eur Urol 2024 Oct;86(4):315-326. Epub 2024 May 14 doi: 10.1016/j.eururo.2024.04.031. PMID: 38749852
Congenital urinary tract obstruction.
Cheung KW, Morris RK, Kilby MD
Best Pract Res Clin Obstet Gynaecol 2019 Jul;58:78-92. Epub 2019 Jan 11 doi: 10.1016/j.bpobgyn.2019.01.003. PMID: 30819578
Benefits and limitations of animal models in partial bladder outlet obstruction for translational research.
Kitta T, Kanno Y, Chiba H, Higuchi M, Ouchi M, Togo M, Moriya K, Shinohara N
Int J Urol 2018 Jan;25(1):36-44. Epub 2017 Oct 1 doi: 10.1111/iju.13471. PMID: 28965358
Pharmacologic management of non-neurogenic functional obstruction in women.
Cohn JA, Brown ET, Reynolds WS, Kaufman MR, Dmochowski RR
Expert Opin Drug Metab Toxicol 2016 Jun;12(6):657-67. Epub 2016 Apr 28 doi: 10.1080/17425255.2016.1178239. PMID: 27095013
Bladder neck contractures and the prostate cancer survivor.
Song JS, Eswara JR, Brandes SB
Curr Opin Urol 2014 Jul;24(4):389-94. doi: 10.1097/MOU.0000000000000065. PMID: 24901516

Recent systematic reviews

Bladder Outlet Obstruction Relief and Symptom Improvement Following Medical and Surgical Therapies for Lower Urinary Tract Symptoms Suggestive of Benign Prostatic Hyperplasia: A Systematic Review.
Creta M, Russo GI, Bhojani N, Drake MJ, Gratzke C, Peyronnet B, Roehrborn C, Tikkinen KAO, Cornu JN, Fusco F
Eur Urol 2024 Oct;86(4):315-326. Epub 2024 May 14 doi: 10.1016/j.eururo.2024.04.031. PMID: 38749852
Use of the penile cuff test to diagnose bladder outlet obstruction: A systematic review and meta-analysis.
Khosla L, Codelia-Anjum A, Sze C, Martinez Diaz S, Zorn KC, Bhojani N, Elterman D, Chughtai B
Low Urin Tract Symptoms 2022 Sep;14(5):318-328. Epub 2022 Jun 18 doi: 10.1111/luts.12454. PMID: 35716000
Bladder neck stenosis after transurethral prostate surgery: a systematic review and meta-analysis.
Castellani D, Wroclawski ML, Pirola GM, Gauhar V, Rubilotta E, Chan VW, Cheng BK, Gubbiotti M, Galosi AB, Herrmann TRW, Teoh JY
World J Urol 2021 Nov;39(11):4073-4083. Epub 2021 May 11 doi: 10.1007/s00345-021-03718-1. PMID: 33974100
Progressive bladder remodeling due to bladder outlet obstruction: a systematic review of morphological and molecular evidences in humans.
Fusco F, Creta M, De Nunzio C, Iacovelli V, Mangiapia F, Li Marzi V, Finazzi Agrò E
BMC Urol 2018 Mar 9;18(1):15. doi: 10.1186/s12894-018-0329-4. PMID: 29519236Free PMC Article
A Systematic Review and Meta-analysis of Functional Outcomes and Complications Following Transurethral Procedures for Lower Urinary Tract Symptoms Resulting from Benign Prostatic Obstruction: An Update.
Cornu JN, Ahyai S, Bachmann A, de la Rosette J, Gilling P, Gratzke C, McVary K, Novara G, Woo H, Madersbacher S
Eur Urol 2015 Jun;67(6):1066-1096. Epub 2014 Jun 25 doi: 10.1016/j.eururo.2014.06.017. PMID: 24972732

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