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Urethral obstruction

MedGen UID:
12015
Concept ID:
C0041972
Disease or Syndrome
Synonyms: Obstruction, Urethral; Obstructions, Urethral; Urethral Obstruction; Urethral Obstructions
SNOMED CT: Obstruction of urethra (95588004); Urethral obstruction (95588004)
 
HPO: HP:0000796
Monarch Initiative: MONDO:0001556

Definition

Obstruction of the flow of urine through the urethra. [from HPO]

Conditions with this feature

Ochoa syndrome
MedGen UID:
98015
Concept ID:
C0403555
Congenital Abnormality
Urofacial syndrome (UFS) is characterized by prenatal or infantile onset of urinary bladder voiding dysfunction, abnormal facial movement with expression (resulting from abnormal co-contraction of the corners of the mouth and eyes), and often bowel dysfunction (constipation and/or encopresis). Bladder voiding dysfunction increases the risk for urinary incontinence, megacystis, vesicoureteric reflux, hydroureteronephrosis, urosepsis, and progressive renal impairment. In rare instances, an individual who has (a) a molecularly confirmed diagnosis and/or (b) an affected relative meeting clinical diagnostic criteria manifests only the characteristic facial features or only the urinary bladder voiding dysfunction (not both). Nocturnal lagophthalmos (incomplete closing of the eyes during sleep) appears to be a common and significant finding.
Cervical ribs, Sprengel anomaly, anal atresia, and urethral obstruction
MedGen UID:
318617
Concept ID:
C1832391
Disease or Syndrome

Professional guidelines

PubMed

Robakiewicz P, Halfacree Z
J Feline Med Surg 2023 Mar;25(3):1098612X231159073. doi: 10.1177/1098612X231159073. PMID: 36867077
Nakai H, Hyuga T, Kawai S, Kubo T, Nakamura S
Investig Clin Urol 2017 Jun;58(Suppl 1):S46-S53. Epub 2017 Jun 7 doi: 10.4111/icu.2017.58.S1.S46. PMID: 28612060Free PMC Article
Cohn JA, Brown ET, Reynolds WS, Kaufman MR, Dmochowski RR
Expert Opin Drug Metab Toxicol 2016 Jun;12(6):657-67. Epub 2016 Apr 28 doi: 10.1080/17425255.2016.1178239. PMID: 27095013

Recent clinical studies

Etiology

Flores-Torres J, Sanchez-Valle A, Duncan JR, Panzarino V, Rodriguez JM, Kirby RS
Adv Pediatr 2023 Aug;70(1):131-144. Epub 2023 May 15 doi: 10.1016/j.yapd.2023.03.001. PMID: 37422291
Capone V, Persico N, Berrettini A, Decramer S, De Marco EA, De Palma D, Familiari A, Feitz W, Herthelius M, Kazlauskas V, Liebau M, Manzoni G, Maternik M, Mosiello G, Schanstra JP, Vande Walle J, Wühl E, Ylinen E, Zurowska A, Schaefer F, Montini G
Nat Rev Urol 2022 May;19(5):295-303. Epub 2022 Feb 8 doi: 10.1038/s41585-022-00563-8. PMID: 35136187
Zaid UB, Lavien G, Peterson AC
Curr Urol Rep 2016 Apr;17(4):33. doi: 10.1007/s11934-016-0588-0. PMID: 26902627
Cimador M, Vallasciani S, Manzoni G, Rigamonti W, De Grazia E, Castagnetti M
Nat Rev Urol 2013 Nov;10(11):657-66. Epub 2013 Aug 6 doi: 10.1038/nrurol.2013.164. PMID: 23917119
Badlani GH
J Endourol 1997 Dec;11(6):473-5. doi: 10.1089/end.1997.11.473. PMID: 9440859

Diagnosis

Flores-Torres J, Sanchez-Valle A, Duncan JR, Panzarino V, Rodriguez JM, Kirby RS
Adv Pediatr 2023 Aug;70(1):131-144. Epub 2023 May 15 doi: 10.1016/j.yapd.2023.03.001. PMID: 37422291
Capone V, Persico N, Berrettini A, Decramer S, De Marco EA, De Palma D, Familiari A, Feitz W, Herthelius M, Kazlauskas V, Liebau M, Manzoni G, Maternik M, Mosiello G, Schanstra JP, Vande Walle J, Wühl E, Ylinen E, Zurowska A, Schaefer F, Montini G
Nat Rev Urol 2022 May;19(5):295-303. Epub 2022 Feb 8 doi: 10.1038/s41585-022-00563-8. PMID: 35136187
Goldman HB
Urol Clin North Am 2011 Feb;38(1):31-7, vi. doi: 10.1016/j.ucl.2010.12.005. PMID: 21353077
Hodges SJ, Patel B, McLorie G, Atala A
ScientificWorldJournal 2009 Oct 14;9:1119-26. doi: 10.1100/tsw.2009.127. PMID: 19838598Free PMC Article
Tseng TY, Stoller ML
Clin Geriatr Med 2009 Aug;25(3):437-43. doi: 10.1016/j.cger.2009.06.003. PMID: 19765491

Therapy

Capone V, Persico N, Berrettini A, Decramer S, De Marco EA, De Palma D, Familiari A, Feitz W, Herthelius M, Kazlauskas V, Liebau M, Manzoni G, Maternik M, Mosiello G, Schanstra JP, Vande Walle J, Wühl E, Ylinen E, Zurowska A, Schaefer F, Montini G
Nat Rev Urol 2022 May;19(5):295-303. Epub 2022 Feb 8 doi: 10.1038/s41585-022-00563-8. PMID: 35136187
Lee B, Vangipuram R, Petersen E, Tyring SK
Dermatol Online J 2018 Jul 15;24(7) PMID: 30261561
Cohn JA, Brown ET, Reynolds WS, Kaufman MR, Dmochowski RR
Expert Opin Drug Metab Toxicol 2016 Jun;12(6):657-67. Epub 2016 Apr 28 doi: 10.1080/17425255.2016.1178239. PMID: 27095013
Bazi T, Abou-Ghannam G, Khauli R
Int Urogynecol J 2013 Sep;24(9):1435-44. Epub 2013 Feb 14 doi: 10.1007/s00192-013-2055-5. PMID: 23408001
Badlani GH
J Endourol 1997 Dec;11(6):473-5. doi: 10.1089/end.1997.11.473. PMID: 9440859

Prognosis

Capone V, Persico N, Berrettini A, Decramer S, De Marco EA, De Palma D, Familiari A, Feitz W, Herthelius M, Kazlauskas V, Liebau M, Manzoni G, Maternik M, Mosiello G, Schanstra JP, Vande Walle J, Wühl E, Ylinen E, Zurowska A, Schaefer F, Montini G
Nat Rev Urol 2022 May;19(5):295-303. Epub 2022 Feb 8 doi: 10.1038/s41585-022-00563-8. PMID: 35136187
Peyton CC, Badlani GH
Can J Urol 2015 Oct;22 Suppl 1:75-81. PMID: 26497347
Hodges SJ, Patel B, McLorie G, Atala A
ScientificWorldJournal 2009 Oct 14;9:1119-26. doi: 10.1100/tsw.2009.127. PMID: 19838598Free PMC Article
Rosenblum N, Nitti VW
Curr Opin Urol 2001 Jul;11(4):411-6. doi: 10.1097/00042307-200107000-00013. PMID: 11429503
Badlani GH
J Endourol 1997 Dec;11(6):473-5. doi: 10.1089/end.1997.11.473. PMID: 9440859

Clinical prediction guides

Bolgeo T, Maconi A, Bertolotti M, Roveta A, Betti M, Gatti D, Boccafoschi C
Arch Ital Urol Androl 2020 Dec 18;92(4) doi: 10.4081/aiua.2020.4.314. PMID: 33348955
Cohn JA, Brown ET, Reynolds WS, Kaufman MR, Dmochowski RR
Expert Opin Drug Metab Toxicol 2016 Jun;12(6):657-67. Epub 2016 Apr 28 doi: 10.1080/17425255.2016.1178239. PMID: 27095013
Liu H, Zhang G, Niu Y, Jiang N, Xiao W
Rheumatol Int 2014 Dec;34(12):1665-70. Epub 2014 Apr 23 doi: 10.1007/s00296-014-3002-6. PMID: 24756854
Routh JC, McGee SM, Ashley RA, Reinberg Y, Vandersteen DR
J Urol 2010 Oct;184(4 Suppl):1615-9. Epub 2010 Aug 21 doi: 10.1016/j.juro.2010.03.119. PMID: 20728183
Barry MJ
Urology 2001 Dec;58(6 Suppl 1):25-32; discussion 32. doi: 10.1016/s0090-4295(01)01300-0. PMID: 11750246

Recent systematic reviews

Khondker A, Kim K, Najafabadi BT, Nguyen DD, Kim JK, Yadav P, Brownrigg N, Richter J, E Chua M, Dos Santos J, Rickard M, Lorenzo AJ
World J Urol 2023 Jul;41(7):1803-1811. Epub 2023 Jun 17 doi: 10.1007/s00345-023-04451-7. PMID: 37330439
Khondker A, Chan JY, Malik S, Kim JK, Chua ME, Henderson B, Yadav P, Santos JD, Brownrigg N, Viteri B, Tasian GE, Rickard M, Lorenzo AJ
J Pediatr Urol 2023 Aug;19(4):408-417. Epub 2023 Feb 23 doi: 10.1016/j.jpurol.2023.02.008. PMID: 36906479Free PMC Article
Nassr AA, Shazly SAM, Abdelmagied AM, Araujo Júnior E, Tonni G, Kilby MD, Ruano R
Ultrasound Obstet Gynecol 2017 Jun;49(6):696-703. doi: 10.1002/uog.15988. PMID: 27270578
Hennus PM, de Kort LM, Bosch JL, de Jong TP, van der Heijden GJ
PLoS One 2014;9(2):e85474. Epub 2014 Feb 20 doi: 10.1371/journal.pone.0085474. PMID: 24586242Free PMC Article
Tonni G, Vito I, Ventura A, Grisolia G, De Felice C
Arch Gynecol Obstet 2013 Feb;287(2):187-94. Epub 2012 Nov 9 doi: 10.1007/s00404-012-2615-9. PMID: 23138754

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