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Benign neoplasm of pituitary gland

MedGen UID:
141679
•Concept ID:
C0496901
•
Neoplastic Process
Synonyms: Benign Neoplasm of Pituitary; benign neoplasm of pituitary; Benign Neoplasm of Pituitary Gland; benign neoplasm of pituitary gland; Benign Neoplasm of the Pituitary; benign neoplasm of the pituitary; Benign Neoplasm of the Pituitary Gland; benign neoplasm of the pituitary gland; Benign Pituitary Gland Neoplasm; benign pituitary gland neoplasm; Benign Pituitary Gland Tumor; benign pituitary gland tumor; benign pituitary gland tumour; Benign Pituitary Neoplasm; benign pituitary neoplasm; Benign Pituitary Tumor; benign pituitary tumor; benign pituitary tumour; Benign Tumor of Pituitary; benign tumor of pituitary; Benign tumor of pituitary gland; Benign Tumor of Pituitary Gland; benign tumor of pituitary gland; Benign Tumor of the Pituitary; benign tumor of the pituitary; Benign Tumor of the Pituitary Gland; benign tumor of the pituitary gland; benign tumour of pituitary; benign tumour of pituitary gland; benign tumour of the pituitary; benign tumour of the pituitary gland; pituitary gland benign neoplasm; Pituitary Neoplasms, Benign; pituitary neoplasms, benign; Pituitary Tumor, Benign; pituitary tumor, benign
SNOMED CT: Benign tumor of pituitary gland (92296004); Benign neoplasm of pituitary gland (92296004)
 
Monarch Initiative: MONDO:0021439

Definition

A neoplasm that arises from the anterior or posterior lobe of pituitary gland and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBenign neoplasm of pituitary gland

Professional guidelines

PubMed

Pituitary Incidentalomas: Best Practices and Looking Ahead.
Giraldi E, Allen JW, Ioachimescu AG
Endocr Pract 2023 Jan;29(1):60-68. Epub 2022 Oct 18 doi: 10.1016/j.eprac.2022.10.004. PMID: 36270609
Treatment of Cushing's Syndrome: An Endocrine Society Clinical Practice Guideline.
Nieman LK, Biller BM, Findling JW, Murad MH, Newell-Price J, Savage MO, Tabarin A; Endocrine Society
J Clin Endocrinol Metab 2015 Aug;100(8):2807-31. Epub 2015 Jul 29 doi: 10.1210/jc.2015-1818. PMID: 26222757Free PMC Article
The Treatment of Cushing's Disease.
Pivonello R, De Leo M, Cozzolino A, Colao A
Endocr Rev 2015 Aug;36(4):385-486. Epub 2015 Jun 11 doi: 10.1210/er.2013-1048. PMID: 26067718Free PMC Article

Recent clinical studies

Etiology

Single-cell sequencing identifies differentiation-related markers for molecular classification and recurrence prediction of PitNET.
Zhang Q, Yao B, Long X, Chen Z, He M, Wu Y, Qiao N, Ma Z, Ye Z, Zhang Y, Yao S, Wang Y, Cheng H, Chen H, Ye H, Wang Y, Li Y, Chen J, Zhang Z, Guo F, Zhao Y
Cell Rep Med 2023 Feb 21;4(2):100934. Epub 2023 Feb 7 doi: 10.1016/j.xcrm.2023.100934. PMID: 36754052Free PMC Article
Overview of the 2022 WHO Classification of Pituitary Tumors.
Asa SL, Mete O, Perry A, Osamura RY
Endocr Pathol 2022 Mar;33(1):6-26. Epub 2022 Mar 15 doi: 10.1007/s12022-022-09703-7. PMID: 35291028
Craniopharyngiomas primarily affecting the hypothalamus.
Pascual JM, Prieto R, Rosdolsky M
Handb Clin Neurol 2021;181:75-115. doi: 10.1016/B978-0-12-820683-6.00007-5. PMID: 34238481
Pituitary disease and pregnancy.
Valassi E
Endocrinol Diabetes Nutr (Engl Ed) 2021 Mar;68(3):184-195. Epub 2021 Jun 12 doi: 10.1016/j.endien.2020.07.002. PMID: 34167698
Clinical and Pathological Aspects of Silent Pituitary Adenomas.
Drummond J, Roncaroli F, Grossman AB, Korbonits M
J Clin Endocrinol Metab 2019 Jul 1;104(7):2473-2489. doi: 10.1210/jc.2018-00688. PMID: 30020466Free PMC Article

Diagnosis

Overview of the 2022 WHO Classification of Pituitary Tumors.
Asa SL, Mete O, Perry A, Osamura RY
Endocr Pathol 2022 Mar;33(1):6-26. Epub 2022 Mar 15 doi: 10.1007/s12022-022-09703-7. PMID: 35291028
Primary sellar melanocytoma.
Claus M, Van Der Linden M, Van Dorpe J, Lapauw B, T'Sjoen G
Pituitary 2021 Dec;24(6):970-977. Epub 2021 Sep 13 doi: 10.1007/s11102-021-01186-9. PMID: 34518998
Pituitary disease and pregnancy.
Valassi E
Endocrinol Diabetes Nutr (Engl Ed) 2021 Mar;68(3):184-195. Epub 2021 Jun 12 doi: 10.1016/j.endien.2020.07.002. PMID: 34167698
Neuroimaging of the Pituitary Gland: Practical Anatomy and Pathology.
Chapman PR, Singhal A, Gaddamanugu S, Prattipati V
Radiol Clin North Am 2020 Nov;58(6):1115-1133. Epub 2020 Sep 17 doi: 10.1016/j.rcl.2020.07.009. PMID: 33040852
Evolution of Pituitary Surgery.
Deopujari CE, Shaikh ST
Neurol India 2020 May-Jun;68(Supplement):S33-S38. doi: 10.4103/0028-3886.287673. PMID: 32611890

Therapy

Role of radiosurgery in the treatment of Cushing's disease.
Losa M, Albano L, Bailo M, Barzaghi LR, Mortini P
J Neuroendocrinol 2022 Aug;34(8):e13134. Epub 2022 Aug 18 doi: 10.1111/jne.13134. PMID: 35980263
Complications in Endoscopic Pituitary Surgery.
Vignolles-Jeong J, Kreatsoulas D, Godil S, Otto B, Carrau R, Prevedello D
Otolaryngol Clin North Am 2022 Apr;55(2):431-448. doi: 10.1016/j.otc.2021.12.011. PMID: 35365316
The imaging of immunotherapy-related hypophysitis and other pituitary lesions in oncology patients.
Lasocki A, Iravani A, Galligan A
Clin Radiol 2021 May;76(5):325-332. Epub 2021 Feb 14 doi: 10.1016/j.crad.2020.12.028. PMID: 33593600
Use of radiotherapy after pituitary surgery for non-functioning pituitary adenomas.
Chanson P, Dormoy A, Dekkers OM
Eur J Endocrinol 2019 Jul;181(1):D1-D13. doi: 10.1530/EJE-19-0058. PMID: 31048560
Xanthomatous hypophysitis.
Hanna B, Li YM, Beutler T, Goyal P, Hall WA
J Clin Neurosci 2015 Jul;22(7):1091-7. Epub 2015 May 6 doi: 10.1016/j.jocn.2015.01.019. PMID: 25957783

Prognosis

Pituitary Incidentalomas: Best Practices and Looking Ahead.
Giraldi E, Allen JW, Ioachimescu AG
Endocr Pract 2023 Jan;29(1):60-68. Epub 2022 Oct 18 doi: 10.1016/j.eprac.2022.10.004. PMID: 36270609
Autophagy and Pituitary Adenoma.
Wu Z, Gu W
Adv Exp Med Biol 2020;1207:183-194. doi: 10.1007/978-981-15-4272-5_12. PMID: 32671747
Surgery for Acromegaly.
Sarkar S, Chacko AG
Neurol India 2020 May-Jun;68(Supplement):S44-S51. doi: 10.4103/0028-3886.287664. PMID: 32611892
Imaging findings in hypophysitis: a review.
Caranci F, Leone G, Ponsiglione A, Muto M, Tortora F, Muto M, Cirillo S, Brunese L, Cerase A
Radiol Med 2020 Mar;125(3):319-328. Epub 2019 Dec 20 doi: 10.1007/s11547-019-01120-x. PMID: 31863360
Clinical and Pathological Aspects of Silent Pituitary Adenomas.
Drummond J, Roncaroli F, Grossman AB, Korbonits M
J Clin Endocrinol Metab 2019 Jul 1;104(7):2473-2489. doi: 10.1210/jc.2018-00688. PMID: 30020466Free PMC Article

Clinical prediction guides

Single-cell sequencing identifies differentiation-related markers for molecular classification and recurrence prediction of PitNET.
Zhang Q, Yao B, Long X, Chen Z, He M, Wu Y, Qiao N, Ma Z, Ye Z, Zhang Y, Yao S, Wang Y, Cheng H, Chen H, Ye H, Wang Y, Li Y, Chen J, Zhang Z, Guo F, Zhao Y
Cell Rep Med 2023 Feb 21;4(2):100934. Epub 2023 Feb 7 doi: 10.1016/j.xcrm.2023.100934. PMID: 36754052Free PMC Article
Architects of Pituitary Tumour Growth.
Sabatino ME, Grondona E, De Paul AL
Front Endocrinol (Lausanne) 2022;13:924942. Epub 2022 Jun 28 doi: 10.3389/fendo.2022.924942. PMID: 35837315Free PMC Article
Surgery for Acromegaly.
Sarkar S, Chacko AG
Neurol India 2020 May-Jun;68(Supplement):S44-S51. doi: 10.4103/0028-3886.287664. PMID: 32611892
Imaging findings in hypophysitis: a review.
Caranci F, Leone G, Ponsiglione A, Muto M, Tortora F, Muto M, Cirillo S, Brunese L, Cerase A
Radiol Med 2020 Mar;125(3):319-328. Epub 2019 Dec 20 doi: 10.1007/s11547-019-01120-x. PMID: 31863360
MicroRNAs in pituitary tumors.
Wierinckx A, Roche M, Legras-Lachuer C, Trouillas J, Raverot G, Lachuer J
Mol Cell Endocrinol 2017 Nov 15;456:51-61. Epub 2017 Jan 13 doi: 10.1016/j.mce.2017.01.021. PMID: 28089822

Recent systematic reviews

Genetic aspects of pituitary carcinoma: A systematic review.
Yang Z, Zhang T, Gao H
Medicine (Baltimore) 2016 Nov;95(47):e5268. doi: 10.1097/MD.0000000000005268. PMID: 27893664Free PMC Article
Primary pituitary lymphoma: an update of the literature.
Tarabay A, Cossu G, Berhouma M, Levivier M, Daniel RT, Messerer M
J Neurooncol 2016 Dec;130(3):383-395. Epub 2016 Aug 31 doi: 10.1007/s11060-016-2249-z. PMID: 27581598
Pituitary stalk lesions: systematic review and clinical guidance.
Catford S, Wang YY, Wong R
Clin Endocrinol (Oxf) 2016 Oct;85(4):507-21. Epub 2016 Apr 13 doi: 10.1111/cen.13058. PMID: 26950774
Gene and protein expression in pituitary corticotroph adenomas: a systematic review of the literature.
Seltzer J, Ashton CE, Scotton TC, Pangal D, Carmichael JD, Zada G
Neurosurg Focus 2015 Feb;38(2):E17. doi: 10.3171/2014.10.FOCUS14683. PMID: 25639319
Metastatic involvement of the pituitary gland: a systematic review with pooled individual patient data analysis.
He W, Chen F, Dalm B, Kirby PA, Greenlee JD
Pituitary 2015 Feb;18(1):159-68. doi: 10.1007/s11102-014-0552-2. PMID: 24445565

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