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Intracranial Neoplasm

MedGen UID:
287152
•Concept ID:
C1527390
•
Neoplastic Process
Synonyms: Intracranial Neoplasms; Neoplasm, Intracranial; Neoplasms, Intracranial
SNOMED CT: Intracranial neoplasm (254935002); Intracranial tumor (254935002); ICT - Intracranial tumor (254935002)

Definition

A benign or malignant neoplasm that arises from or metastasizes to structures within the cranium. This includes meningeal and other tumors that occur in the spaces that surround the brain, and neoplasms of the brain. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVIntracranial Neoplasm

Professional guidelines

PubMed

Molecular diagnosis and treatment of meningiomas: an expert consensus (2022).
Deng J, Hua L, Bian L, Chen H, Chen L, Cheng H, Dou C, Geng D, Hong T, Ji H, Jiang Y, Lan Q, Li G, Liu Z, Qi S, Qu Y, Shi S, Sun X, Wang H, You Y, Yu H, Yue S, Zhang J, Zhang X, Wang S, Mao Y, Zhong P, Gong Y; Group of Neuro-Oncology, Society of Neurosurgery, Chinese Medical Association
Chin Med J (Engl) 2022 Aug 20;135(16):1894-1912. doi: 10.1097/CM9.0000000000002391. PMID: 36179152Free PMC Article
Geriatric brain tumor management part I: Meningioma.
Cohen-Inbar O
J Clin Neurosci 2019 Sep;67:5-9. Epub 2019 Jun 14 doi: 10.1016/j.jocn.2019.05.063. PMID: 31208835
Introduction: surgical management of skull base meningiomas.
Zada G, Başkaya MK, Shah MV
Neurosurg Focus 2017 Oct;43(VideoSuppl2):Intro. doi: 10.3171/2017.10.FocusVid.Intro. PMID: 28967307

Recent clinical studies

Etiology

Brain metastases: An update on the multi-disciplinary approach of clinical management.
Mitchell DK, Kwon HJ, Kubica PA, Huff WX, O'Regan R, Dey M
Neurochirurgie 2022 Jan;68(1):69-85. Epub 2021 Apr 14 doi: 10.1016/j.neuchi.2021.04.001. PMID: 33864773Free PMC Article
Geriatric brain tumor management part II: Glioblastoma multiforme.
Cohen-Inbar O
J Clin Neurosci 2019 Sep;67:1-4. Epub 2019 Jun 18 doi: 10.1016/j.jocn.2019.05.064. PMID: 31227406
Geriatric brain tumor management part I: Meningioma.
Cohen-Inbar O
J Clin Neurosci 2019 Sep;67:5-9. Epub 2019 Jun 14 doi: 10.1016/j.jocn.2019.05.063. PMID: 31208835
Intraventricular Tumors.
Agarwal A, Kanekar S
Semin Ultrasound CT MR 2016 Apr;37(2):150-8. Epub 2015 Dec 10 doi: 10.1053/j.sult.2015.12.003. PMID: 27063665
Pediatric pseudotumor cerebri.
Phillips PH
Int Ophthalmol Clin 2012 Summer;52(3):51-9, xii. doi: 10.1097/IIO.0b013e31825a12f6. PMID: 22668539

Diagnosis

Headache in Brain Tumors.
Cho S, Chu MK
Neurol Clin 2024 May;42(2):487-496. Epub 2024 Jan 12 doi: 10.1016/j.ncl.2023.12.004. PMID: 38575261
Brain Metastases: A Modern Multidisciplinary Approach.
O'Halloran PJ, Gutierrez E, Kalyvas A, Mohan N, Atallah S, Kalia S, Millar BA, Laperriere N, Conrad T, Zadeh G, Bernstein M, Shultz DB, Kongkham P
Can J Neurol Sci 2021 Mar;48(2):189-197. Epub 2020 Oct 12 doi: 10.1017/cjn.2020.224. PMID: 33040758
Intraventricular Tumors.
Agarwal A, Kanekar S
Semin Ultrasound CT MR 2016 Apr;37(2):150-8. Epub 2015 Dec 10 doi: 10.1053/j.sult.2015.12.003. PMID: 27063665
Appropriate use of neuroimaging in headache.
Kuruvilla DE, Lipton RB
Curr Pain Headache Rep 2015 Jun;19(6):17. doi: 10.1007/s11916-015-0490-3. PMID: 26017709
Pediatric pseudotumor cerebri.
Phillips PH
Int Ophthalmol Clin 2012 Summer;52(3):51-9, xii. doi: 10.1097/IIO.0b013e31825a12f6. PMID: 22668539

Therapy

An insight into the risk factors of brain tumors and their therapeutic interventions.
Rasheed S, Rehman K, Akash MSH
Biomed Pharmacother 2021 Nov;143:112119. Epub 2021 Aug 30 doi: 10.1016/j.biopha.2021.112119. PMID: 34474351
Molecular and translational advances in meningiomas.
Suppiah S, Nassiri F, Bi WL, Dunn IF, Hanemann CO, Horbinski CM, Hashizume R, James CD, Mawrin C, Noushmehr H, Perry A, Sahm F, Sloan A, Von Deimling A, Wen PY, Aldape K, Zadeh G; International Consortium on Meningiomas
Neuro Oncol 2019 Jan 14;21(Suppl 1):i4-i17. doi: 10.1093/neuonc/noy178. PMID: 30649490Free PMC Article
Patterns in neurosurgical adverse events: intracranial neoplasm surgery.
Wong JM, Panchmatia JR, Ziewacz JE, Bader AM, Dunn IF, Laws ER, Gawande AA
Neurosurg Focus 2012 Nov;33(5):E16. doi: 10.3171/2012.7.FOCUS12183. PMID: 23116096
MicroRNAs-based network: a novel therapeutic agent in pituitary adenoma.
Shi X, Tao B, He H, Sun Q, Fan C, Bian L, Zhao W, Lu YC
Med Hypotheses 2012 Mar;78(3):380-4. Epub 2012 Jan 4 doi: 10.1016/j.mehy.2011.12.001. PMID: 22222153
Bioenergetics pathways and therapeutic resistance in gliomas: emerging role of mitochondria.
Griguer CE, Oliva CR
Curr Pharm Des 2011;17(23):2421-7. doi: 10.2174/138161211797249251. PMID: 21827418

Prognosis

Brain Metastases: A Modern Multidisciplinary Approach.
O'Halloran PJ, Gutierrez E, Kalyvas A, Mohan N, Atallah S, Kalia S, Millar BA, Laperriere N, Conrad T, Zadeh G, Bernstein M, Shultz DB, Kongkham P
Can J Neurol Sci 2021 Mar;48(2):189-197. Epub 2020 Oct 12 doi: 10.1017/cjn.2020.224. PMID: 33040758
A Practical Overview on the Molecular Biology of Meningioma.
Delgado-López PD, Cubo-Delgado E, González-Bernal JJ, Martín-Alonso J
Curr Neurol Neurosci Rep 2020 Nov 2;20(12):62. doi: 10.1007/s11910-020-01084-w. PMID: 33136206
Geriatric brain tumor management part II: Glioblastoma multiforme.
Cohen-Inbar O
J Clin Neurosci 2019 Sep;67:1-4. Epub 2019 Jun 18 doi: 10.1016/j.jocn.2019.05.064. PMID: 31227406
Molecular and translational advances in meningiomas.
Suppiah S, Nassiri F, Bi WL, Dunn IF, Hanemann CO, Horbinski CM, Hashizume R, James CD, Mawrin C, Noushmehr H, Perry A, Sahm F, Sloan A, Von Deimling A, Wen PY, Aldape K, Zadeh G; International Consortium on Meningiomas
Neuro Oncol 2019 Jan 14;21(Suppl 1):i4-i17. doi: 10.1093/neuonc/noy178. PMID: 30649490Free PMC Article
Intraventricular Tumors.
Agarwal A, Kanekar S
Semin Ultrasound CT MR 2016 Apr;37(2):150-8. Epub 2015 Dec 10 doi: 10.1053/j.sult.2015.12.003. PMID: 27063665

Clinical prediction guides

Brain metastases: An update on the multi-disciplinary approach of clinical management.
Mitchell DK, Kwon HJ, Kubica PA, Huff WX, O'Regan R, Dey M
Neurochirurgie 2022 Jan;68(1):69-85. Epub 2021 Apr 14 doi: 10.1016/j.neuchi.2021.04.001. PMID: 33864773Free PMC Article
Autophagy inhibition enhances anti-pituitary adenoma effect of tetrandrine.
Lyu L, Hu Y, Yin S, Wang L, Ye F, Wang M, Zhou Y, Ma W, Chen C, Jiang Y, Wang Z, Jiang S, Zhou P, Wang X
Phytother Res 2021 Jul;35(7):4007-4021. Epub 2021 May 26 doi: 10.1002/ptr.7117. PMID: 34038010
A Practical Overview on the Molecular Biology of Meningioma.
Delgado-López PD, Cubo-Delgado E, González-Bernal JJ, Martín-Alonso J
Curr Neurol Neurosci Rep 2020 Nov 2;20(12):62. doi: 10.1007/s11910-020-01084-w. PMID: 33136206
Geriatric brain tumor management part I: Meningioma.
Cohen-Inbar O
J Clin Neurosci 2019 Sep;67:5-9. Epub 2019 Jun 14 doi: 10.1016/j.jocn.2019.05.063. PMID: 31208835
Molecular and translational advances in meningiomas.
Suppiah S, Nassiri F, Bi WL, Dunn IF, Hanemann CO, Horbinski CM, Hashizume R, James CD, Mawrin C, Noushmehr H, Perry A, Sahm F, Sloan A, Von Deimling A, Wen PY, Aldape K, Zadeh G; International Consortium on Meningiomas
Neuro Oncol 2019 Jan 14;21(Suppl 1):i4-i17. doi: 10.1093/neuonc/noy178. PMID: 30649490Free PMC Article

Recent systematic reviews

Extra-skeletal intracranial mesenchymal chondrosarcoma: systematic-literature review.
Kumarasamy S, Garg K, Garg A, Sharma MC, Singh M, Chandra PS, Kale SS
Childs Nerv Syst 2024 Sep;40(9):2723-2733. Epub 2024 May 19 doi: 10.1007/s00381-024-06452-2. PMID: 38762839
Giant Cavernous Malformation Mimicking an Infiltrative Intracranial Neoplasm in Children-Case Report and Systematic Review of the Literature.
González-Gallardo E, Rauschenbach L, Santos AN, Riess C, Li Y, Tippelt S, Della Marina A, Dohna-Schwake C, Sure U, Dammann P
World Neurosurg 2023 Jun;174:30-41. Epub 2023 Mar 6 doi: 10.1016/j.wneu.2023.02.135. PMID: 36889633
Medulloblastoma cancer stem cells: molecular signatures and therapeutic targets.
Bahmad HF, Poppiti RJ
J Clin Pathol 2020 May;73(5):243-249. Epub 2020 Feb 7 doi: 10.1136/jclinpath-2019-206246. PMID: 32034059
Genetic aspects of pituitary carcinoma: A systematic review.
Yang Z, Zhang T, Gao H
Medicine (Baltimore) 2016 Nov;95(47):e5268. doi: 10.1097/MD.0000000000005268. PMID: 27893664Free PMC Article
Distant metastases in meningioma: an underestimated problem.
Surov A, Gottschling S, Bolz J, Kornhuber M, Alfieri A, Holzhausen HJ, Abbas J, Kösling S
J Neurooncol 2013 May;112(3):323-7. Epub 2013 Feb 13 doi: 10.1007/s11060-013-1074-x. PMID: 23404622

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